Themes: SEROTONIN

2019

Contained in: Neuropharmacology, 2019: 145, 37-48

Gene-environment interactions informing therapeutic approaches to cognitive and affective disorders

Authors: Rogers, J., Renoir T., Hannan A.J.

  Environmental enrichment, exercise on serotonergic signaling and cognitive/affective disorders - Review
  Rogers, J., Renoir T., Hannan A.J. - 2019

  REVIEWS AND COMMENTARIES   ENVIRONMENT AND SOCIAL BEHAVIOR   LOCOMOTOR ACTIVITY   NEUROGENESIS AND PLASTICITY   SEROTONIN   NEUROTROPHIC FACTORS
Contained in: Neuropharmacology, 2019: 145, 13-24

Enviornmental enrichment, alone or in combination with various pharmacotherapies. confers marked benefits after traumatic brain injury

Authors: de la Tremblaye, P.B., Cheng J.P., Bondi C.O., Kline A.E.

  Environemntal enrichment and 5-HT1A agonists/acetylcholinesterase inhibitors/D2 receptor agonists exposure after traumatic brain injury benefits - Review
  de la Tremblaye, P.B., Cheng J.P., Bondi C.O., Kline A.E. - 2019

  ACETYLCHOLINE   REVIEWS AND COMMENTARIES   ENVIRONMENT AND SOCIAL BEHAVIOR   CENTRAL NERVOUS SYSTEM LESIONS   SEROTONIN   DOPAMINE
Contained in: Brain Res. Bull., 2019: 146, 213-223

Cognitive and anxiety-like impairments accompanied by serotonergic uultrastructural and immunohistochemical alterations in early stages of parkinsonism

Authors: Leal, P.C., Bispo J.M.M., Lins L.C.R.F., Souza M.F., Gois A.M., Moore G., Marchioro M., Ribeiro A.M., Silva R.H., Meshul C.K., Santos J.R.

  Reserpine exposure on dorsal raphe nucleus/hippocampal/prefrontal seroton neuronal system/tyrosine hydroxylase expression and locomotion/exploration in rats: Parkinsonism early stage rat model
  Leal, P.C., Bispo J.M.M., Lins L.C.R.F., Souza M.F., Gois A.M., Moore G., Marchioro M., Ribeiro A.M., Silva R.H., Meshul C.K., Santos J.R. - 2019

  HIPPOCAMPUS, FORNIX AND SUBICULUM   SEROTONIN   CEREBRAL CORTEX   LOCOMOTOR ACTIVITY   EXPLORATORY ACTIVITY   DORSAL AND MEDIAL RAPHE NUCLEI   CENTRAL NERVOUS SYSTEM LESIONS
Contained in: Brain Res. Bull., 2019: 146, 279-286

Atorvastatin prevents lipopolysaccharide-induced depressive-like behaviour in mice

Authors: Taniguti, E.H., Ferreira Y.S., Stupp I.J.V., Fraga-Junior E.B., Doneda D.L., Lopes L., Rios-Santos F., Lima E., Buss Z.S., Viola G.G., Vandresen-Filho S.

  Atarvostatin and fluoxetine exposure on lipopolysaccharide effects on hippocampal/prefrontal oxidative stress/BDNF/TNF levels, locomotion/exploration and response to stress in mice
  Taniguti, E.H., Ferreira Y.S., Stupp I.J.V., Fraga-Junior E.B., Doneda D.L., Lopes L., Rios-Santos F., Lima E., Buss Z.S., Viola G.G., Vandresen-Filho S. - 2019

  SEROTONIN   NEUROTROPHIC FACTORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   CEREBRAL CORTEX   STRESS   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY
Contained in: Brain Res. Bull., 2019: 146, 302-309

Ro41-5253, a selective antagonist of retinoic acid receptor α, ameliorates chronic unpredictable mild stress-induced depressive-like behaviors in rats: involvement of regulating HPA axis and improving hippocampal neuronal deficits

Authors: Ke, Q., Li R., Cai L., Wu S., Li C.

  Fluoxetine and retinoic acid receptor α antagonists on chornic unpredictable stress exposure effects on hypothalamic CRH/glucocorticoid receptor expression, hippocampal BDNF/synapse-related proteins, sucrose preference, locomotion/exploration/rearing/grooming, response to stress and related serum corticosterone levels in rats
  Ke, Q., Li R., Cai L., Wu S., Li C. - 2019

  STRESS   SEROTONIN   PROTEINS AND GENES   NEUROTROPHIC FACTORS   HYPOTHALAMUS   PITUITARY-ADRENAL AXIS   CORTICO-RELEASING-FACTOR (CRF)   HIPPOCAMPUS, FORNIX AND SUBICULUM   GLUCOCORTICOIDS   STEROTYPED BEHAVIORS
Contained in: Brain Res. Bull., 2019: 146, 310-319

Acid sphingomyelinase controls dopamine activity and responses to appetitive stimuli in mice

Authors: Kalinichenko, L.S., Hammad L., Reichel M., Kohl Z., Gulbins E., Kornhuber J., Muller C.P.

  Acid sphingomyelinase role in accumbal/hippocampal dopamine/norepinephrine/serotonin levels related to alcohol on palatable food exposure in mice
  Kalinichenko, L.S., Hammad L., Reichel M., Kohl Z., Gulbins E., Kornhuber J., Muller C.P. - 2019

  DOPAMINE   SEROTONIN   EPINEPHRINE AND NOREPINEPHRINE   NUCLEUS ACCUMBENS   HIPPOCAMPUS, FORNIX AND SUBICULUM   FEEDING AND DRINKING
Contained in: Neuropharmacology, 2019: 146, 12-18

Synergistic effect of aripiprazole and escitalopram in increasiung serotonin but not norepinephrine neurotransmission in the rat hippocampus

Authors: Ebrahimzadeh, M., Mansari M.E., Blier P.

  Escitalopram and aripiprazole on hippocampal serotonin and norepinephrine levels nd related neuronal firing in rats
  Ebrahimzadeh, M., Mansari M.E., Blier P. - 2019

  SEROTONIN   EPINEPHRINE AND NOREPINEPHRINE   HIPPOCAMPUS, FORNIX AND SUBICULUM
Contained in: Neurosci. Lett., 2019: 693, 54-57

New tools for understanding coping and resilience

Authors: Baratta, M.V., Maier S.F.

  Brain circuitry related to stress resilinece - Review
  Baratta, M.V., Maier S.F. - 2019

  REVIEWS AND COMMENTARIES   STRESS   SEROTONIN   DORSAL AND MEDIAL RAPHE NUCLEI   STRIATUM   SUBSTANTIA NIGRA   CEREBRAL CORTEX
Contained in: Pharmacol. Biochem. Behav., 2019: 178, 39-41

The test retest model of anxiety: an appraisal of findings to explain benzodiazepine tolerance

Authors: Bourin, M.

  Ethological model of anxiety in rodents and benzodiazepines tolerance - Review
  Bourin, M. - 2019

  REVIEWS AND COMMENTARIES   ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   γ-AMINO-BUTYRIC ACID (GABA)   SEROTONIN   LOCOMOTOR ACTIVITY
Contained in: Neuroscience, 2019: 401, 59-72

Natural killer cells may exert antidepressant-like effects in mice by controlling the release of inflammatory factors

Authors: Hu, L., Li D., Ge C., Liao H., Wang Y., Xu H.

  Natural killer cells role in chronic stress and fluoxetine exposure effects on hippocampal serotonin/dopamine/norepinephrine levels, serum inflammatory factors levels, exploratory/rearing behavior and response to stress in mice
  Hu, L., Li D., Ge C., Liao H., Wang Y., Xu H. - 2019

  STRESS   EXPLORATORY ACTIVITY   NEUROPEPTIDES   STEROTYPED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   SEROTONIN   DOPAMINE   EPINEPHRINE AND NOREPINEPHRINE   STRAIN
Contained in: Neurosci. Behav. Physiol., 2019: 49, 178-183

Optogenetic studies of the pathophysiological mechanisms and treatment of depression

Authors: Dygalo, N.N., Shishkina G.T.
Contained in: Psychopharmacology, 2019: 236, 449-461

Translational tests involving non-reward: methodological considerations

Authors: Phillips, B.U., Lopez-Cruz L., Saksida L.M., Bussey T.J.

  Reward omission, ratio schedules and extinction in operant responding: major depressive and obsessive compulsive disorder animal models - Review
  Phillips, B.U., Lopez-Cruz L., Saksida L.M., Bussey T.J. - 2019

  REVIEWS AND COMMENTARIES   SCHEDULE INDUCED CONDITIONING AND BEHAVIOR   OPERANT CONDITIONING   DOPAMINE   SEROTONIN   EXTINCTION   STRESS
Contained in: Prog. Neurobiol., 2019: 173, 54-87

Pathologic role of nitrergic neurotransmission in mood disorders

Authors: Ghasemi, M., Claunch J., Niu K.
Contained in: Psychopharmacology, 2019: 236, 591-602

Resveratrol exerts a protective effect in chronic unpredictable mild stress-induced depressive-like behavior: involvement of the AKT/GSK3β signaling pathway in hippocampus

Authors: Shen, J., Qu C., Xu L., Sun H., Zhang J.

  Fluoxetine, PI3K antagonist LY294002 and resveratrol exposure on stress effects on hippocampal/cortical inflammatory markers levels/AKT-GSK3β protein expression, sucrose preference, exploration/grooming/rearing and response to stress in rats
  Shen, J., Qu C., Xu L., Sun H., Zhang J. - 2019

  STRESS   PROTEIN KINASES   HIPPOCAMPUS, FORNIX AND SUBICULUM   SEROTONIN   EXPLORATORY ACTIVITY   NEUROPEPTIDES   CEREBRAL CORTEX   STEROTYPED BEHAVIORS
Contained in: Behav. Brain Res., 2019: 360, 341-353

Role of nitric oxide in the induction of the behavioral and cellular changes produce by a common aversive stimulus in Aplysia

Authors: Farruggella, J., Acebo J., Lloyd L., Wainwright M.L., Mozzachiodi R.

  NO signaling on serotonergic neuron excitability related to aversive suppressing feeding in Aplysia
  Farruggella, J., Acebo J., Lloyd L., Wainwright M.L., Mozzachiodi R. - 2019

  NITRIC AND NITROUS OXIDE   CONDITIONED AND UNCONDITIONED INHIBITION   SEROTONIN   FEAR AND RELATED BEHAVIORS
Contained in: Behav. Brain Res., 2019: 361, 50-53

Fear but not social behaviour is affected by a polymorphism in the 5'-flanking region of the serotonin transporter (5-HTT) gene in adult hens

Authors: Krause, E.T., Kjaer J.B., Dudde A., Schrader L., Phi-van L.

  5-HT transporter gene on fear and social related behaviors in adult hens
  Krause, E.T., Kjaer J.B., Dudde A., Schrader L., Phi-van L. - 2019

  FEAR AND RELATED BEHAVIORS   ENVIRONMENT AND SOCIAL BEHAVIOR   SEROTONIN   PROTEINS AND GENES
Contained in: Neurosci. Lett., 2019: 696, 168-173

Effects of escitalopram and ibuprofen on a depression-like phenotype induced by chronic stress in rats

Authors: Seo, M.K., Lee J.G., Park S.W.

  Escitalopram and ibuprofen exposure on stress effects on hippocampal BDNF/protein 11 expression and response to stress in rats
  Seo, M.K., Lee J.G., Park S.W. - 2019

  STRESS   SEROTONIN   NEUROTROPHIC FACTORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   GLUCOCORTICOIDS   PROTEINS AND GENES
Contained in: Neuropharmacology, 2019: 148, 311-319

Role of 5.HT2C receptors of the dorsal hippocampus in the modulation of anxiety- and panic-related defensive responses in rats

Authors: Sant'Ana, A.B., Vilela-Costa H.H., Vicente M.A., Hernandes P.M., de Andrade T.G.C.S., Zangrossi Jr. H.

  Dorsal hippocampal 5-HT2C receptor modulation on nociception, locomotion/exploration, aversive conditioned inhibition and passive avoidance in rats
  Sant'Ana, A.B., Vilela-Costa H.H., Vicente M.A., Hernandes P.M., de Andrade T.G.C.S., Zangrossi Jr. H. - 2019

  SEROTONIN   HIPPOCAMPUS, FORNIX AND SUBICULUM   AVOIDANCE   DARK/LIGHT CONTEXT   CONDITIONED AND UNCONDITIONED INHIBITION   FEAR AND RELATED BEHAVIORS   NOCICEPTION   ANXIOLYTIC DRUGS
Contained in: Behav. Brain Res., 2019: 362, 64-70

The effects of amphetamine on working memory and locomotor activity in adult rats administered risperidone early in life

Authors: Bardgett, M.E., Crane C., Thompson E.C.B., Cox B., Downnen T.

  Adolescence risperidone chronic exposure on locomotor activity, amphetamine exposure, locomotor responsivity, and operant responding in adult male and female rats
  Bardgett, M.E., Crane C., Thompson E.C.B., Cox B., Downnen T. - 2019

  DOPAMINE   LOCOMOTOR ACTIVITY   OPERANT CONDITIONING   GENDER   SEROTONIN   GLUTAMATE
Contained in: Behav. Brain Res., 2019: 362, 140-151

Arachidonoyl serotonin (AA-5-HT) modulates general fear-like behavior and inhibits mesolimbic dopamine release

Authors: Freels, T.G., Laster D.B., Cook M.N.

  TRPV1 channel inhibitor arachidonoyl serotonin (AA-5-HT) modulation on amygdalar/accumbal dopamine release, locomotion/exploration/rearing and fear conditioning extinction in mice of different strain
  Freels, T.G., Laster D.B., Cook M.N. - 2019

  DOPAMINE   STRAIN   AMYGDALA   NUCLEUS ACCUMBENS   SEROTONIN   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   CANNABINOIDS   DARK/LIGHT CONTEXT   EXPLORATORY ACTIVITY   EXTINCTION   FEAR AND RELATED BEHAVIORS   STEROTYPED BEHAVIORS
Contained in: Behav. Brain Res., 2019: 362, 311-318

Psycho-emotional status but not cognition is changed under the combined effect of ionizing radiations at doses related to deep space missions

Authors: Kokhan, V.S., Shakhbazian E.V., Markova N.A.

  Radiation exposure on prefrontal/hypothalamic/amygdalar monoamine content/neurokenin 1 receptor expression, locomoton/exploration/rearing, aggressive behavior, passive avoidance and Morris water maze performance in rats
  Kokhan, V.S., Shakhbazian E.V., Markova N.A. - 2019

  HYPOTHALAMUS   LOCOMOTOR ACTIVITY   STEROTYPED BEHAVIORS   DOPAMINE   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   EPINEPHRINE AND NOREPINEPHRINE   SUBSTANCE P   AGGRESSIVE AND DEFENSIVE BEHAVIOR   EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   AVOIDANCE   SEROTONIN   AMYGDALA   CEREBRAL CORTEX
Contained in: Behav. Brain Res., 2019: 363, 191-198

Impact of early exposure to a cafeteria diet on prefrontal cortex monoamines and novel object recognition in adolescent rats

Authors: Moreton, E., Baron P., Tiplady S., McCall S., Clifford B., Langley-Evans S.C., Fone K.C.F., Voigt J.P.

  Early cafeteria diet exposure on prefrontal Doamine/serotonin levels and object recognition in male and female adolescent rats
  Moreton, E., Baron P., Tiplady S., McCall S., Clifford B., Langley-Evans S.C., Fone K.C.F., Voigt J.P. - 2019

  FEEDING AND DRINKING   CEREBRAL CORTEX   DOPAMINE   SEROTONIN   GENDER
Contained in: Neuron, 2019: 102, 27-47

Obsessive-compulsive disorder: puzzles and prospects

Authors: Robbins, T.W., Vaghi M.M., Banca P.

  Obsessive compulsive disorder - Review
  Robbins, T.W., Vaghi M.M., Banca P. - 2019

  REVIEWS AND COMMENTARIES   PROTEINS AND GENES   OPERANT CONDITIONING   FEAR AND RELATED BEHAVIORS   CEREBRAL CORTEX   STRIATUM   SEROTONIN
Contained in: Neuroscience, 2019: 403, 93-110

The role of depressive subtypes within the neuroinflammation hypothesis of major depressive disorder

Authors: Woelfer, M., Kasties V., Kahlfuss S., Walter M.

  Neuroinflammation and depressive disorders - Review
  Woelfer, M., Kasties V., Kahlfuss S., Walter M. - 2019

  REVIEWS AND COMMENTARIES   SEROTONIN   N-METHYL-D-ASPARTATE (NMDA)   NEUROPEPTIDES   CEREBRAL CORTEX   HYPOTHALAMUS   PITUITARY-ADRENAL AXIS
Contained in: Plos Biol., 2019: 17, e2007097

Serotonin recepro HTR6-mediated mTORC1 signaing regulates dietary restriction-induced memory enhancement

Authors: Teng, L.-L., Lu G.-L., Chiou L.-C., Lin W.-S., Cheng Y.-Y., Hsueh T.-E., Huang Y.-C., Hwang N.-H., Yeh J.-W., Liao R.-M., Fan S.-Z., Yen J.-H., Fu T.-F., Tsai T.-F., Wu M.-S., Wang P.-Y.

  Dietary protein/tryptophan supplementation and HTR6 receptor role in serum corticosterone levels, hippocampal neuron excitability/plasticity/mTOR-PKA-CREB expression, locomotion/exploration and objec recognition in young and aged mice
  Teng, L.-L., Lu G.-L., Chiou L.-C., Lin W.-S., Cheng Y.-Y., Hsueh T.-E., Huang Y.-C., Hwang N.-H., Yeh J.-W., Liao R.-M., Fan S.-Z., Yen J.-H., Fu T.-F., Tsai T.-F., Wu M.-S., Wang P.-Y. - 2019

  SEROTONIN   GLUCOCORTICOIDS   LOCOMOTOR ACTIVITY   EXPLORATORY ACTIVITY   PROTEIN KINASES   PROTEINS AND GENES   NEUROTROPHIC FACTORS   FEEDING AND DRINKING   NEUROGENESIS AND PLASTICITY   HIPPOCAMPUS, FORNIX AND SUBICULUM   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   AGE
Contained in: Neurosci. Behav. Physiol., 2019: 49, 315-322

Effects of buspirone on the behavioral responses of adult male and female rats exposed to stressors at neonatal age

Authors: Mikhailenko, V.A., Butkevich I.P., Vershinina E.A.

  Buspirone exposure on neonatal stress effects on exploratory activity, response to stress and Morris water maze performance in male and female adult rats
  Mikhailenko, V.A., Butkevich I.P., Vershinina E.A. - 2019

  STRESS   GENDER   SEROTONIN   EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY
Contained in: Neurosci. Behav. Physiol., 2019: 49, 341-346

Prenatal effects of fluoxetine on adaptive behavior and the cognitive domain in male rats during the prepubertal period of development

Authors: Butkevich, I.P., Mikhailenko V.A.

  Prenatal fluoxetine exposure on nociception, locomotion/exploration, response to stress and Morris water maze performance in peripubertal male rat offspring
  Butkevich, I.P., Mikhailenko V.A. - 2019

  SEROTONIN   NOCICEPTION   SPATIAL ORIENTATION AND SPATIAL MEMORY   LOCOMOTOR ACTIVITY   EXPLORATORY ACTIVITY   STRESS
Contained in: Behav. Brain Res., 2019: 364, 205-212

Serotonin type 6 receptor antagonist attentuates the impairment of long-term potentiation and memory induced by Abeta

Authors: Shahidi, S., Hashemi-Firouzi N., Asl S.S., Komaki A.

  5HT6 antagonist exposure on intracerebroventricular amyloid β effects on hippocampal neuron excitability, exploratory activity, object recognition and passive avoidance in rats
  Shahidi, S., Hashemi-Firouzi N., Asl S.S., Komaki A. - 2019

  SEROTONIN   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   CENTRAL NERVOUS SYSTEM LESIONS   HIPPOCAMPUS, FORNIX AND SUBICULUM   EXPLORATORY ACTIVITY   AVOIDANCE   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION
Contained in: Behav. Brain Res., 2019: 364, 356-365

N-acetylcysteine attenuates neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat

Authors: Fernandes, J., Gupta G.L.

  N-acetylcysteine or fluoxetine exposure on stress effects on hippocampal/prefrontal serotonin levels/neuroinflammation, locomotor/rearing behavior, sucrose preference and response to stress in rats
  Fernandes, J., Gupta G.L. - 2019

  STRESS   LOCOMOTOR ACTIVITY   SEROTONIN   NEUROPEPTIDES   STEROTYPED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   CEREBRAL CORTEX
Contained in: Behav. Brain Res., 2019: 365, 26-35

Effects of chronic mild stress induced depression on synaptic plasticity in mouse hippocampus

Authors: Hei, M., Chen P., Wang S., Li X., Xu M., Zhu X., Wang Y., Duan J., Huang Y., Zhao S.

  Chornic stress on hippocampal neuron plasticity, brain dopamine/serotonin neurotransmission, exploratory activity, response to stress and Morris water maze performance in mice
  Hei, M., Chen P., Wang S., Li X., Xu M., Zhu X., Wang Y., Duan J., Huang Y., Zhao S. - 2019

  STRESS   HIPPOCAMPUS, FORNIX AND SUBICULUM   SEROTONIN   DOPAMINE   NEUROGENESIS AND PLASTICITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   EXPLORATORY ACTIVITY