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2017
Postnatal proteasome inhibition promotes amyloid-β aggregation in hippocampus and impairs spatial learning in adult mice
Authors: Sunkaria, A., Yadav A., Bhardwaj S., Sandhir R. Post-natal proteasome inhibition on hippocampal calcium-calmodulin dependent kinase II, CREB, AMPA, brain-derived neurotrophic factor and amyloid-β expression and Morris water maze performance in adult mice
Sunkaria, A., Yadav A., Bhardwaj S., Sandhir R. - 2017
Long-term depression of intrinsic excitability accompanied by synaptic depression in cerebellar Purkibìnje cells
Authors: Shim, H.G., Jang D.C., Lee J., Chung G., Lee S., Kim Y.G., Jeon D.E., Kim S.J. Protein kinase C role in cerebellar Purkinje cells excitability/plasticity in mice
Shim, H.G., Jang D.C., Lee J., Chung G., Lee S., Kim Y.G., Jeon D.E., Kim S.J. - 2017
Null EPAC mutants reveal a sequential order of versatile cAMP effects during Drosophila aversive odor learning
Authors: Richlitzki, A., Latour P., Schwarzel M. EPAC protein role in protein kinase A activity and aversive odor-learning in Drosophila
Richlitzki, A., Latour P., Schwarzel M. - 2017
Activation of PERK elicits memory impairment through inactivation of CREB and downregulation of PSD95 after traumatic brain injury
Authors: Sen, T., Gupta R., Kaiser H., Sen N. Traumatic brain injury on PKR-like ER kinase/CREB activity, BDNF/PSD95 protein levels and Morris water maze performance in mice
Sen, T., Gupta R., Kaiser H., Sen N. - 2017
Superior long-term synaptic memory induced by combining dual pharmacological activation of PKA and ERK with an enhanced training protocol
Authors: Liu, R.-Y., Neveu C., Smolen P., Cleary L.J., Byrne J.H. PKA/ERK/CREB signaling on serotonin-induced long-term synaptic facilitation in Aplysia
Liu, R.-Y., Neveu C., Smolen P., Cleary L.J., Byrne J.H. - 2017
Context memory formation requires activity-dependent protein degradation in the hippocampus
Authors: Cullen, P.K., ferrara N.C., Pullins S.E., Helmstetter F.J. Post context pre-exposure intra-hippocampal proteasome inhibition or protein synthesis inhibitor injection on fear conditioning learning in rats
Cullen, P.K., ferrara N.C., Pullins S.E., Helmstetter F.J. - 2017
2016
Nicotinic modulation of hippocampal cell signaling and associated effects on learning and memory
Authors: Kutlu, M.G., Gould T.J. Nicotine on hippocampal long-term potentiation, kinases/CREB expression and spatial learning - Review
Kutlu, M.G., Gould T.J. - 2016
A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25-35-impaired mouse cognitive function
Authors: Zhang, Z., Chen R., An W., Wang C., Liao G., Dong X., Bi A., Yin Z., Luo L. Acetylcholinesterase inhibitor and calcium channel blocker on amyloid-β25-35-induced hippocampal neuron loss/excitability/CREB-Calcium calmodulin kinase II levels and spatial learning impairment in mice
Zhang, Z., Chen R., An W., Wang C., Liao G., Dong X., Bi A., Yin Z., Luo L. - 2016
The positive allosteric modulator of α7 nicotinic acetylcholine receptors, 3-furan-2-yl-N-p-tolyl-acrylamide, enhances memory processes and stimulates ERK1/2 phosphorylation in mice
Authors: Targowska-Duda, K.M., Wnorowski A., Budzynska B., Jozwiak K., Biala G., Arias H.R. α7 nicotinic acetylcholine agonists on locomotor activity, prefrontal/hippocampal extracellular signal-regulated kinase 1/2 expression, passive avoidance acquisition and consolidation in mice
Targowska-Duda, K.M., Wnorowski A., Budzynska B., Jozwiak K., Biala G., Arias H.R. - 2016
The α1 adrenoceptors in ventrolateral orbital cortex contribute to the expression of morphine-induced behavioral sensitization in rats
Authors: Wei, L., Zhu Y.-M., Zhang Y.-X., Liang F., Li T., Gao H.-Y., Huo F.-Q., Yan C.-X. Extracellular signal-regulated kinase modulation of orbitofrontal cortex α1-adrenoceptor role on morphine-induced locomotor sensitization in rats
Wei, L., Zhu Y.-M., Zhang Y.-X., Liang F., Li T., Gao H.-Y., Huo F.-Q., Yan C.-X. - 2016
Neuroligin 2 deletion alters inhibitory synapse function and anxiety-associated neuronal activation in the amygdala
Authors: Babaev, O., Botta P., Meyer E., Muller C., Ehrenreich H., Brose N., Luthi A., Krueger-Burg D. Neuroligin 2 protein on locomotion/exploration and related amygdala c-fos expression in mice
Babaev, O., Botta P., Meyer E., Muller C., Ehrenreich H., Brose N., Luthi A., Krueger-Burg D. - 2016
CaMKII regulates proteasome phosphorylation and activity and promotes memory destabilization following retrieval
Authors: Jarome, T.J., Ferrara N.C., Kwapis J.L., Helmstetter F.J. Fear conditioning retrieval on amygdalar proteasome activity in rats: local calcium calmodulin kinase II inhibitor and anisomycin injection effects on reconsolidation
Jarome, T.J., Ferrara N.C., Kwapis J.L., Helmstetter F.J. - 2016
Neural mechanisms underlying anxiety-chronic pain interactions
Authors: Zhuo, M. Prefrontal and amygdalar neuron excitability role in chronic pain and anxiey - Review
Zhuo, M. - 2016
p38 mitogen-activated protein kinase activation in amygdala mediates κ opioid receptor agonist U50,488H-induced conditioned place aversion
Authors: Zan, G.-Y., Wang Q., Wang Y.-J., Chen J.-C., Wu X., Yang C.-H., Chai J.-R., Li M., Liu Y., Hu X.-W., Shu X.-H., Liu J.-G. Intra-amygdala mitogen-activated protein kinase inhibitor injection on conditioned place aversion by κ opioid agonist in mice
Zan, G.-Y., Wang Q., Wang Y.-J., Chen J.-C., Wu X., Yang C.-H., Chai J.-R., Li M., Liu Y., Hu X.-W., Shu X.-H., Liu J.-G. - 2016
CaMKIIα knockdown decreases anxiety in the open field and low serotonin-induced upregulation of GluA1 in the basolateral amygdala
Authors: Tran, L., Keele N.B. Intra-basolateral amygdala 5,7-dihydroxytryptamine injection on local calcium calmodulin kinase II and GluA1 expression and exploratory activity in rats
Tran, L., Keele N.B. - 2016
Aging-related dysfunction of striatal cholinergic interneurons produces conflict in action selection
Authors: Matamales, M., Skrbis Z., Hatch R.J., Balleine B.W., Gotz J., Bertran-Gonzalez J. Cholinergic thalamo-striatal pathway role in operant conditioning in young and aged mice
Matamales, M., Skrbis Z., Hatch R.J., Balleine B.W., Gotz J., Bertran-Gonzalez J. - 2016
Antidepressant actions of lateral habenula deep brain stimulation differentially correlated with CaMKII/GSK3/AMPK signaling locally and in the infralimbic cortex
Authors: Kim, Y., Morath B., Hu C., Byrne L.K., Sutor S.L., Frye M.A., Tye S.J. Lateral habenula stimulation on local and infralimbic cortex calcium calmodulin kinase II/glycogen synthase kinase 3/5' AMP-activated protein kinase signaling in rats: response to stress and locomotor activity in ACTH- and saline-treated animals
Kim, Y., Morath B., Hu C., Byrne L.K., Sutor S.L., Frye M.A., Tye S.J. - 2016
Sevoflurane postconditioning improves long-term learning and memory of neonatal hypoxia-ischemia brain damage rats via the PI3K/Akt-mPTP pathway
Authors: Lai, Z., Zhang L., Su J., Cai D., Xu Q. Sevoflurane anesthesia after training on Morris water maze performance, object recognition and hippocampal neuronal damage in neonatal hypoxia-ischemia submitted adolescent rats: phosphatydyl inositol-3 kinase/nitric oxide synthase/glycogen synthase kinase-3β pathway modulation
Lai, Z., Zhang L., Su J., Cai D., Xu Q. - 2016
BDNF pathway is involved in the protective effects of SS-31 on isoflurane-induced cognitive deficits in aging mice
Authors: Wu, J., Zhang M., Li H., Sun X., Hao S., Ji M., Yang J. Li K. Peptide 55-31 on isoflurane effects on locomotion/exploration and hippocampal oxidative stress/brain derived neurotrophic factor level/ NMDA-calcium calmodulin kinase II-CREB signaling in aging mice
Wu, J., Zhang M., Li H., Sun X., Hao S., Ji M., Yang J. Li K. - 2016
Studies of mice with cyclic AMP-dependent protein kinase (PKA) defects reveal the cr4iticl role of PKA's catalytic subunits in anxiety
Authors: Briassoulis, G., Keil M.F., Naved B., Liu S., Starost M.F., Nesterova M., Gokarn N., Batistatos A., Wu T.J., Stratakis C.A. Brain protein kinase A expression related to exploratory activity and nociception in mice
Briassoulis, G., Keil M.F., Naved B., Liu S., Starost M.F., Nesterova M., Gokarn N., Batistatos A., Wu T.J., Stratakis C.A. - 2016
Neuroplastin 65 mediates cognitive functions via excitatory/inhibitory synapse imbalance and ERK signal pathway
Authors: Amuti, S., Tang Y., Wu S., Liu L., Huang L., Zhang H., Li H., Jiang F., Wang G., Liu X., Yuan Q. Glicoprotein neuroplastin 65 on synaptic plasticity, locomotion/exploration, Morris water maze performance, passive avoidance and fear conditioning in mice
Amuti, S., Tang Y., Wu S., Liu L., Huang L., Zhang H., Li H., Jiang F., Wang G., Liu X., Yuan Q. - 2016
Reciprocal activation/inactivation of ERK in the amygdala and frontal cortex is correlated with the degree of novelty of an open-field enviornment
Authors: Sanguedo, F.V., Bueno Dias C.V., Cruz Dias F.R., Samuels R.I., Carey R.J., Carrera M.P. Prefrontal, amygdalar and accumbal extracellular signal-regulated kinase expression and exploration habituation in rats
Sanguedo, F.V., Bueno Dias C.V., Cruz Dias F.R., Samuels R.I., Carey R.J., Carrera M.P. - 2016
The effect of surgical and psychological stress on learning and memory function in aged C57BL/6 mice
Authors: Zhang, C., Li C., Xu Z., Zhao S., Li P., Cao J., Mi W. Surgical and psychological stress on cortical and hippocampal Akt/mammalian target of rapamycin/protein kinase C signaling and cognitive performance in aged mice
Zhang, C., Li C., Xu Z., Zhao S., Li P., Cao J., Mi W. - 2016
Reward memory relieves anxiety-related behavior through synaptic strengthening and protein kinase C in dentate gyrus
Authors: Lei, Z., Liu B., Wang J.-H. Protein kinase C inhibitor on exploration, spatial learning and related hippocampal neuron excitability/plasticity in mice
Lei, Z., Liu B., Wang J.-H. - 2016
Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property
Authors: Lee, H.E., Jeon S.J., Ryu B., Park S.J., Ko S.Y., Lee Y., Kim E., Lee S., Kim H., Jang D.S., Ryu J.H. C-glucosylflavone swertisin on locomotion/exploration, scopolamine-induced passive avoidance/spatial learning impairment and cortical and hippocampal protein kinase A/CREB expression in mice: adenosine A1 receptor modulation
Lee, H.E., Jeon S.J., Ryu B., Park S.J., Ko S.Y., Lee Y., Kim E., Lee S., Kim H., Jang D.S., Ryu J.H. - 2016
c-Jun-N-terminal kinase 1 is necessary for nicotine-induced enhancement of contextual fear conditioning
Authors: Leach, P.T., Kenney J.W., Gould T.J. c-Jun-N-terminal kinase 1 on nicotine-induced fear conditioning enhancement in mice
Leach, P.T., Kenney J.W., Gould T.J. - 2016
Modulation of learning and memory by the targeted deletion of the circadian clock gene Bmal1 in forebrain circuits
Authors: Snider, K.H., Dziema H., Aten S., Loeser J., Norona F.E., Hoyt K., Obrietan K. Brain and muscle Arnt-like protein-1 on circadian activity, locomotion, exploration, response to stress, spatial learning and object recognition in mice
Snider, K.H., Dziema H., Aten S., Loeser J., Norona F.E., Hoyt K., Obrietan K. - 2016
Prefrontal cortical regulation of brainwide ciurcuit dynamics and reward-related behavior
Authors: Ferenezi, E.A., Zalocusky K.A., Liston C., Grosenick L., Warden M.R., Amatya D., Katovich K., Mehta H., Patenaude B., Ramakrishnan C., Klanithi P., Etkin A., Knutson B., Glover G.H., Deisseroth K. Prefrontal neuron on midbrain dopaminergic neuron activity, reward processing, locomotor activity, sucrose preference and social/object recognition in rodents
Ferenezi, E.A., Zalocusky K.A., Liston C., Grosenick L., Warden M.R., Amatya D., Katovich K., Mehta H., Patenaude B., Ramakrishnan C., Klanithi P., Etkin A., Knutson B., Glover G.H., Deisseroth K. - 2016
Cell-type-specific control of brainstem locomotor circuits by basal ganglia
Authors: Roseberry, T.K., Lee A.M., Lalive A.L., Wilbrecht L., Bonci A., Kreitzer A.C. Striatal control of mesencephalic locomotor region activity in mice
Roseberry, T.K., Lee A.M., Lalive A.L., Wilbrecht L., Bonci A., Kreitzer A.C. - 2016
PV plasticity sustained through D1/5 dopamine signaling required for long-term memory consolidation
Authors: Karunakaran, S., Chowdhury A., Donato F., Quairiaux C., Michel C.M., Caroni P. Dopaminergic modulation of hippocampal parvalbumin neuron expression during fear conditioning and Morris water maze consolidation in mice
Karunakaran, S., Chowdhury A., Donato F., Quairiaux C., Michel C.M., Caroni P. - 2016