Themes: NOOTROPICS

2014

Contained in: Neurosci. Lett., 2014: 579, 110-113

Prolyl oligopeptidase inhibition decreases extracellular acetylcholine levels in rat hippocampus and prefrontal cortex

Authors: Jalkanen, A.J., Leikas J.V., Forsberg M.M.

  Prolyl-oligopeptidase inhibitor on hippocampal and prefrontal acetylcholine release in rats
  Jalkanen, A.J., Leikas J.V., Forsberg M.M. - 2014

  ACETYLCHOLINE   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Behav. Brain Res., 2014: 275, 1-10

Xanthohumol improved cognitive flexibility in young mice

Authors: Zamzow, D.R., Elias V., Legette L.C.L., Choi J., Stevens J.F., Magnusson K.R.

  Flavonoid xanthohumol on fatty acid levels and spatial learning in young and adult mice
  Zamzow, D.R., Elias V., Legette L.C.L., Choi J., Stevens J.F., Magnusson K.R. - 2014

  ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS
Contained in: Neurobiol. Learn. Mem., 2014: 116, 117-131

Silibinin ameliorates LPS-induced memory deficits in experimental animals

Authors: Joshi, R., Garabadu D., Teja G.R., Krishnamurthy S.

  Flavonoid silibininon spatial learning, exploratory activity and acetylcholinesterase activity impairment by intracerebroventricular lipopolysaccharide-induced neuroinflammation in rats
  Joshi, R., Garabadu D., Teja G.R., Krishnamurthy S. - 2014

  ACETYLCHOLINE   EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2014: 127, 101-110

Naringin ameliorates memory deficits in experimental paradigm of Alzheimer's disease by attenuating mitochondrial dysfunction

Authors: Sachdeva, A.K., Kuhad A., Chopra K.

  Nootropic effects of naringin on intracerebroventricular streptozotocin rat amnesic model: exploratory activity, Morris water maze performance and hippocampal/cortical antioxidant study
  Sachdeva, A.K., Kuhad A., Chopra K. - 2014

  ACETYLCHOLINE   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Physiol. Behav., 2014: 123, 187-192

Guanfacine ameliorates hypobaric hypoxia induced spatial working memory deficits

Authors: Kauser, H., Sahu S., Kumar S., Panjwani U.

  Guanfacine on spatial working memory deficit by hypoxia in rats
  Kauser, H., Sahu S., Kumar S., Panjwani U. - 2014

  EPINEPHRINE AND NOREPINEPHRINE   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2014: 117, 92-103

Silibinin pretreatment attenuates biochemical and behavioral changes induced by intrastriatal MPP + injection in rats

Authors: Geed, M., Garabadu D., Ahmad A., Krishnamurthy S.

  Silibinin on dopaminergic neurotoxicity by intra-striatal MPP + in rats: locomotory/exploratory and excitoxicity study
  Geed, M., Garabadu D., Ahmad A., Krishnamurthy S. - 2014

  EPINEPHRINE AND NOREPINEPHRINE   LATERALITY AND ASYMMETRICAL INTERVENTIONS   EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   DOPAMINE   NITRIC AND NITROUS OXIDE   NOOTROPICS   SEROTONIN   STRIATUM
Contained in: Psychopharmacology, 2014: 231, 3879-3888

Green tea extract enhances parieto-frontal connectivity during working memory processing

Authors: Schmidt, A., Hammann F., Wolnerhanssen B., Meyer-Gerspach A.C., Drewe J., Beglinger C., Borgwardt S.

  Green tea extract on parieto-frontal connectivity and working memory in humans
  Schmidt, A., Hammann F., Wolnerhanssen B., Meyer-Gerspach A.C., Drewe J., Beglinger C., Borgwardt S. - 2014

  LATERALITY AND ASYMMETRICAL INTERVENTIONS   BRAIN IMAGING   CEREBRAL CORTEX   NOOTROPICS   NEUROGENESIS AND PLASTICITY
Contained in: Pharmacol. Biochem. Behav., 2014: 120, 88-94

Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice

Authors: Jung, I.H., Lee H.E., Park S.J., Ahn Y.J., Kwon G., Woo H., Lee S.Y., Kim J.S., Jo Y.-W., Jang D.S., Kang S.S., Ryu J.H.

  Spinosin flavonoid on hippocampal extracellular signal-regulated kinase/CREB, exploratory activity and memory impairment by scopolamine in mice: 5-HT1A agonists modulation
  Jung, I.H., Lee H.E., Park S.J., Ahn Y.J., Kwon G., Woo H., Lee S.Y., Kim J.S., Jo Y.-W., Jang D.S., Kang S.S., Ryu J.H. - 2014

  EXPLORATORY ACTIVITY   AVOIDANCE   ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   SEROTONIN   PROTEINS AND GENES
Contained in: Pharmacol. Biochem. Behav., 2014: 122, 7-15

Asiaticoside attenuates memory impairment induced by transient cerebral ischemia-reperfusion in mice through anti-inflammatory mechanism

Authors: Chen, S., Yin Z.-J., Jiang C., Ma Z.-Q., Fu Q., Qu R., Ma S.-P.

  Asiaticoside on ischemia-induced Morris water maze and passive avoidance impairment in mice: hippocampal nitric oxide, interleukin and mitogen-activated protein kinase/extracellular signal-regulated kinase changes
  Chen, S., Yin Z.-J., Jiang C., Ma Z.-Q., Fu Q., Qu R., Ma S.-P. - 2014

  AVOIDANCE   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROPEPTIDES   NITRIC AND NITROUS OXIDE   NOOTROPICS   PROTEIN KINASES
Contained in: Neurosci. Lett., 2014: 572, 58-62

Spicatoside A enhances memory consolidation through the brain-derived neurotrophic factor in mice

Authors: Kwon, U., Lee R.E., Lee D.H., Woo H., Park S.J., Gao Q., Ahn Y.J., Son K.H., Ryu J.H.

  Spicatoside A on passive avoidance consolidation via brain derived neurotrophic factor modulation in mice
  Kwon, U., Lee R.E., Lee D.H., Woo H., Park S.J., Gao Q., Ahn Y.J., Son K.H., Ryu J.H. - 2014

  AVOIDANCE   NEUROTROPHIC FACTORS   NOOTROPICS   CONSOLIDATION
Contained in: Brain Res. Bull., 2014: 108, 67-73

Oroxylin A enhances memory consolidation through the brain-derived neurotrophic factor in mice

Authors: Kim, D.H., Lee Y., Lee H.E., Park S.J., Jeon S.J., Jeon S.J., Cheong J.H., Shin C.Y., Son K.H., Ryu J.H.

  Flavonoid oroxylin A on hippocampal brain derived neurotrophic factor and passive avoidance consolidation in mice
  Kim, D.H., Lee Y., Lee H.E., Park S.J., Jeon S.J., Jeon S.J., Cheong J.H., Shin C.Y., Son K.H., Ryu J.H. - 2014

  AVOIDANCE   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NOOTROPICS   CONSOLIDATION
Contained in: Nat. Neurosci., 2014: 17, 1798-1803

Enhancing dentate gyrus function with dietary flavanols improves cognition in older adults

Authors: Brickman, A.M., Khan U.A., Provenzano F.A., Yeung L.-K., Suzuki W., Schroeter H., Wall M., Sloan R.P., Small S.A.

  Cocoa-flavanols on hippocampal functionality and cognition in old humans
  Brickman, A.M., Khan U.A., Provenzano F.A., Yeung L.-K., Suzuki W., Schroeter H., Wall M., Sloan R.P., Small S.A. - 2014

  BRAIN IMAGING   AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: J. Neurosci., 2014: 34,7862-7870

Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults

Authors: Witte, A.V., Kerti L., Margulies D.S., Floel A.

  Resveratrol on blood neurotrophic factors, leptin levels, hippocampal functional connectivity and memory retention in old humans
  Witte, A.V., Kerti L., Margulies D.S., Floel A. - 2014

  BRAIN IMAGING   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROPEPTIDES   NEUROTROPHIC FACTORS   NOOTROPICS
Contained in: Cell. Mol. Neurobiol., 2014: 34. 611-617

Low dose ZD7288 attenuates the ischemia/reperfusion-induced impairment of long-term potentiation induction at hippocampal Schaffer collateral-CA1 synapses

Authors: He, W., Xu X., Lv Q., Guo L.

  Hyperpolarization-activated cyclic nucleotide–gated channels blocker ZD7288 on by ischemia hippocampal long-term potentiation impairment and NR2B/PSD-95 mRNA expression in rats
  He, W., Xu X., Lv Q., Guo L. - 2014

  CENTRAL NERVOUS SYSTEM LESIONS   HIPPOCAMPUS, FORNIX AND SUBICULUM   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS   PROTEINS AND GENES
Contained in: Cell. Mol. Neurobiol., 2014: 34, 797-804

Anti-apoptotic and anti-oxidative roles of quercetin after traumatic brain injury

Authors: Yang, T., Kong B., Gu J.-W., Kuang Y.-Q., Cheng L., Yang W.-T., Xia X., Shu H.-F.

  Quercetin effects on Morris water maze impairment, brain inflammation, apoptosis and oxidative stress by traumatic brain injury in rats
  Yang, T., Kong B., Gu J.-W., Kuang Y.-Q., Cheng L., Yang W.-T., Xia X., Shu H.-F. - 2014

  CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   NEUROPEPTIDES   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2014: 126, 181-186

Curcumin ameliorates cognitive deficits heavy ion irradiation-induced learning and memory deficits through enhancing of Nrf2 antioxidant signaling pathways

Authors: Xie, Y., Zhao Q.Y., Li H.Y., Zhou X., Liu Y., Zhang H.

  Curcumin on spatial memory impairment and cortical oxidative stress by heavy ion irradiation in mice
  Xie, Y., Zhao Q.Y., Li H.Y., Zhou X., Liu Y., Zhang H. - 2014

  CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   NOOTROPICS
Contained in: Brain Res., 2014: 1585, 159-166

SUN11602 has basic fibroblast growth factor-like activity and attenuates neuronal damage and cognitive deficits in a rat model of Alzheimer's disease induced by amyloid β and excitatory amino acids

Authors: Ogino, R., Murayama N., Noshita T., Takemoto N., Toba T., Oka T., Narii N., Yoshida S., Ueno N., Inoue T.

  Neuroprotective SUN11602 on spatial learning impairment induce by hippocampal lesions or Aβ1-40 local injection in rats
  Ogino, R., Murayama N., Noshita T., Takemoto N., Toba T., Oka T., Narii N., Yoshida S., Ueno N., Inoue T. - 2014

  CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Neurosci. Lett., 2014: 583, 170-175

ID1201, the ethanolic extract of the fruit of Melia toosendan ameliorates impairments in spatial learning and reduces levels of amyloid beta in 5XFAD mice

Authors: Cho, W.-H., Park J.-C., Kim D.-H., Kim M.-S., Lee S.-Y., Park H., Kang J.-H., Yeon S.-W., Han J.-S.

  Melia toosendan ethanolic extract on spatial learning deficit by amyloid β peptide in mice
  Cho, W.-H., Park J.-C., Kim D.-H., Kim M.-S., Lee S.-Y., Park H., Kang J.-H., Yeon S.-W., Han J.-S. - 2014

  CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2014: 126, 136-145

NMDA receptors interact with the retrieval memory enhancing effect of pioglitazone in mice

Authors: Almasi-Nasrabadi, M., Gharedaghi M.H., Rezazadeh P., Dehpour A.R., Javadi-Paydar M.

  Pioglitazone on scopolamine and MK-801 spatial learning and retrieval impairment in mice
  Almasi-Nasrabadi, M., Gharedaghi M.H., Rezazadeh P., Dehpour A.R., Javadi-Paydar M. - 2014

  ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS   RECALL AND RECONSOLIDATION
Contained in: Hippocampus, 2014: 24, 44-53

The neuroprotection of Rattin against amyloid β peptide in spatial memory and synaptic plasticity of rats

Authors: Wang, Z.-J., Han W.-N., Yang G.-Z., Yuan L., Liu X.-J., Li Q.-S., Qi J.-S.

  Rattin neuropeptide protection agonist amyloid β peptide formation, spatial learning and hippocampal long-term potentiation in rats
  Wang, Z.-J., Han W.-N., Yang G.-Z., Yuan L., Liu X.-J., Li Q.-S., Qi J.-S. - 2014

  SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   NEUROPEPTIDES   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2014: 117, 47-51

Berberine rescues D-galactose-induced synaptic/memory impairment by regulating the levels of Arc

Authors: Zhan, P.-Y., Cai-Xia P., Lin-Hong Z.

  Berberine on D-galactose-induced synaptic memory impairment in rats: Arc, c-fos and zif268 expression
  Zhan, P.-Y., Cai-Xia P., Lin-Hong Z. - 2014

  SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   PROTEINS AND GENES
Contained in: Behav. Brain Res., 2014: 264, 173-180

Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation

Authors: Xu, P., Wang S., Yu X., Su Y., Wang T., Zhou W., Zhang H., Wang Y., Liu R.

  Rutin on Morris water maze performance and oxidative stress levels in Alzheimer's disease transgenic mice
  Xu, P., Wang S., Yu X., Su Y., Wang T., Zhou W., Zhang H., Wang Y., Liu R. - 2014

  SPATIAL ORIENTATION AND SPATIAL MEMORY   NEUROPEPTIDES   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2014: 120, 73-81

Protective effects of ginsenoside Rgl on chronic restraint stress induced learning and memory impairments in male mice

Authors: Wang, Y., Kan H., Yin Y., Wu W., Hu W., Wang M., Li W., Li W.

  Ginsenoside Rg1 on chronic stress effects on Morris water maze performance and cortical and hippocampal neuron damage in mice
  Wang, Y., Kan H., Yin Y., Wu W., Hu W., Wang M., Li W., Li W. - 2014

  SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   STRESS
Contained in: Behav. Brain Res., 2014: 266, 153-160

Gastrodin ameliorates depression-like behaviors and up¬regulates proliferation of hippocampal-derived neural stem cells in rats: involvement of its anti-inflammatory action

Authors: Wang, H., Zhang R., Qiao Y., Xue F., Nie H., Zhang Z., Wang Y., Peng Z., Tan Q.

  Gastrodin on hippocampal neurogenesis, interleukin 1β levels, response to stress, neophobia and Morris water maze performance in rats
  Wang, H., Zhang R., Qiao Y., Xue F., Nie H., Zhang Z., Wang Y., Peng Z., Tan Q. - 2014

  SPATIAL ORIENTATION AND SPATIAL MEMORY   NEOPHOBIA   NEUROPEPTIDES   NOOTROPICS   NEUROGENESIS AND PLASTICITY   STRESS
Contained in: Neurosci. Lett., 2014: 573, 58-63

Xanthoceraside rescues learning and memory deficits through attenuating beta-amyloid deposition and tau hyperphosphorylation in APP mice

Authors: Jin, G., Wang L.-H., Ji X.-F., Chi T.-Y., Qi Y., Jiao Q., Xu Q., Zhou X.-Y., Zhang R., Zou L.-B.

  Xanthoceraside and donezepil on Learning deficit by β-amyloid in mice
  Jin, G., Wang L.-H., Ji X.-F., Chi T.-Y., Qi Y., Jiao Q., Xu Q., Zhou X.-Y., Zhang R., Zou L.-B. - 2014

  SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Behav. Brain Res., 2014: 270, 196-205

Chronic administration of quercetin prevent spatial learning and memory deficits provoked by chronic stress in rats

Authors: Mohammadi, H.S., Goudarzi I., Lashkarbolouki T., Abrari K., Salmani M.E.

  Chronic stress on hippocampal neuron oxidative stressa and Morris water maze performance in rats: queretin effects
  Mohammadi, H.S., Goudarzi I., Lashkarbolouki T., Abrari K., Salmani M.E. - 2014

  ACETYLCHOLINE   GLUCOCORTICOIDS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   STRESS
Contained in: Neurosci. Lett., 2014: 578, 7-11

Rosiglitazone prevents the memory deficits induced by amyloid-beta oligomers via inhibition of inflammatory responses

Authors: Xu, S., Guan Q., Wang C., Wei X., Chen X., Zheng B., Zhang P.A., Chang L., Zhou W., Mody I., Wang Q.

  Rosiglitazone on hippocampal long-term potentiation and Morris water maze impairment induced by amyloid-β oligomers in rats
  Xu, S., Guan Q., Wang C., Wei X., Chen X., Zheng B., Zhang P.A., Chang L., Zhou W., Mody I., Wang Q. - 2014

  SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   NEUROPEPTIDES   NOOTROPICS
Contained in: Cell. Mol. Neurobiol., 2014: 34, 577-589

Standard extract of Bacopa monniera (CDRI-08) improves contextual fear memory by differentially regulating the activity of histone acetylation and protein phosphatases (PPlα, PP2A) in hippocampus

Authors: Preethi, J., Singh H.K., Venkataraman J.S., Rajan K.E.

  Bacopa monniera extract and histone deacetylase inhibitor on fear conditioning and hippocampal extracellular signal-regulated kinase/CREB and brain-derived neurotrophic factor expression in young rats
  Preethi, J., Singh H.K., Venkataraman J.S., Rajan K.E. - 2014

  FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NOOTROPICS   PROTEIN KINASES   SEROTONIN   PROTEINS AND GENES
Contained in: Behav. Brain Res., 2014: 268, 88-93

Fingolimod increases brain-derived neurotrophic factor levels and ameliorates amygdaloid β-induced memory impairment

Authors: Fukumoto, K., Mizoguchi H., Takeuchi H., Horiuchi H., Kawanokuchi J., Jin S., Mizuno T., Suzumura A.

  Fingolimod on cerebral brain-derived neurotrophic factor levels and amyloid-induced fear conditioning and object recognition impairment in mice
  Fukumoto, K., Mizoguchi H., Takeuchi H., Horiuchi H., Kawanokuchi J., Jin S., Mizuno T., Suzumura A. - 2014

  FEAR AND RELATED BEHAVIORS   NEUROTROPHIC FACTORS   NOOTROPICS
Contained in: Neuroscience, 2014: 277, 383-391

Long-term inhibition of RHO-kinase restores the LTP impaired in chronic forebrain ischemia rats by regulating GABAA and GABAB receptors

Authors: Huang, L., Zhao L.B., Yu Z.Y., He X.J., Ma L.P., Li N., Guo L.J., Feng W.Y.

  Rho-kinase inhibitor on hippocampal long-term potentiation impairment by ischemia in rats: GABA-A/B receptors modulation
  Huang, L., Zhao L.B., Yu Z.Y., He X.J., Ma L.P., Li N., Guo L.J., Feng W.Y. - 2014

  γ-AMINO-BUTYRIC ACID (GABA)   HIPPOCAMPUS, FORNIX AND SUBICULUM   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   NOOTROPICS