2018

Contained in: Physiol. Behav., 2018: 193, 223-231

Homeostatic and non-homeostatic controls of feeding behavior: distinct vs. common neural systems

Authors: Liu, C.M., Kanoski S.E.

  Homeostatic and non-homeostatic mechanisms of feeding control - Review
  Liu, C.M., Kanoski S.E. - 2018

  FEEDING AND DRINKING   HYPOTHALAMUS   CEREBRAL CORTEX   DOPAMINE   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   NUCLEUS ACCUMBENS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROPEPTIDES   REVIEWS AND COMMENTARIES
Contained in: Physiol. Behav., 2018: 194, 568-576

Effects of gymnemic acids lozenge on reward region response to receipt and anticipated receipt of high-sugar food

Authors: Stice, E., Yokum S.

  Gymnesic acids exposure on taste, high-sugar food intake and related brain activity in humans
  Stice, E., Yokum S. - 2018

  FEEDING AND DRINKING   TASTE   BRAIN IMAGING   STRIATUM   LATERALITY AND ASYMMETRICAL INTERVENTIONS   CEREBELLUM   CEREBRAL CORTEX   NUCLEUS ACCUMBENS
Contained in: Neurosci. Res., 2018: 134, 56-60

Optogenetic activation of granule cells in the dorsal dentate gyrus enhances dopaminergic neurotransmission in the nucleus accumbens

Authors: Tritschler, L., Kheirbek M.A., Le Dantec Y., Mendez-David I., Guilloux J.-P., Faye C., Doan J., Pham T.H., Hen R., David D.J., Gardier A.M.

  dentate gyrus optogenetic activation on accumbal dopamine levels in mice
  Tritschler, L., Kheirbek M.A., Le Dantec Y., Mendez-David I., Guilloux J.-P., Faye C., Doan J., Pham T.H., Hen R., David D.J., Gardier A.M. - 2018

  ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   HIPPOCAMPUS, FORNIX AND SUBICULUM   DOPAMINE   NUCLEUS ACCUMBENS   SEPTUM   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION
Contained in: Neurosci. Lett., 2018: 681, 56-61

Intra-accumbal administration of AMN082, a metabotropic glutamte receptor type 7 allosteric agonist, inhibits the acquisition but not the expression of morphine-induced conditioned place preference in rats

Authors: Vatankhah, M., Karimi-Haghighi S., Sarihi A., Haghparast A.

  Intra-accumbens mGluR7 agonist on locomotor activity and conditioned place preference by morphine acquisition and retrieval in rats
  Vatankhah, M., Karimi-Haghighi S., Sarihi A., Haghparast A. - 2018

  GLUTAMATE   NUCLEUS ACCUMBENS   OPIOIDS   CLASSICAL PAVLOVIAN CONDITIONING   LOCOMOTOR ACTIVITY
Contained in: Neuroscience, 2018: 386, 121-136

Contingency training alters neurobiological components of emotional resilience in male and female rats

Authors: Kent, M., Scott S., Lambert S., Kirk E., Terhune-Cotter B., Thompson B., Neal S., Dozier B., Bardi M., Lambert K.

  Contingency training and chronic unpredictable stress on exploratory activity, spatial learning and related hippocampal/lateral habenula brain-derived neurotrophic factor/neuropeptide Y and brain c-fos expression in male and female rats
  Kent, M., Scott S., Lambert S., Kirk E., Terhune-Cotter B., Thompson B., Neal S., Dozier B., Bardi M., Lambert K. - 2018

  GENDER   SPATIAL ORIENTATION AND SPATIAL MEMORY   OPERANT CONDITIONING   STEROTYPED BEHAVIORS   EXPLORATORY ACTIVITY   STRESS   GLUCOCORTICOIDS   PROTEINS AND GENES   CEREBRAL CORTEX   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   AMYGDALA   NUCLEUS ACCUMBENS   SEPTUM   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NEUROPEPTIDES
Contained in: Neuropharmacology, 2018: 137, 322-331

Dissociable contribution of dorsal and ventral striatal regions on a rodent cost/benefit decision-making task requiring cognitive effort

Authors: Silveira, M.M., Tremblay M., Winstanley C.A.

  Dorsomedial striatal and accumbal inactivation on operant responding in rats
  Silveira, M.M., Tremblay M., Winstanley C.A. - 2018

  STRIATUM   NEURAL REVERSIBLE INACTIVATIONS   NUCLEUS ACCUMBENS   OPERANT CONDITIONING   SCHEDULE INDUCED CONDITIONING AND BEHAVIOR
Contained in: Nat. Rev. Neurosci., 2018: 19, 535-551

Brain circuit dysfunction in post-traumatic stress disorder: from mouse to man

Authors: Fenster, R.J., Lebois L.A.M., Ressler K.J., Suh J.

  Post-traumatic stress disorder brain circuits from rodents to primates - Review
  Fenster, R.J., Lebois L.A.M., Ressler K.J., Suh J. - 2018

  STRESS   REVIEWS AND COMMENTARIES   HIPPOCAMPUS, FORNIX AND SUBICULUM   CEREBRAL CORTEX   AMYGDALA   CEREBELLUM   STRIATUM   SEPTUM   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   NUCLEUS ACCUMBENS   FEAR AND RELATED BEHAVIORS   AVOIDANCE   AGGRESSIVE AND DEFENSIVE BEHAVIOR   ENVIRONMENT AND SOCIAL BEHAVIOR
Contained in: Nat. Neurosci., 2018: 21, 1072-1083

Dopamine neurons create Pavlovian conditioned stimuli with circuit-defined motivational properties

Authors: Saunders, B.T., Richard J.M., Margolis E.B., Janak P.H.

  Ventral tegmental area/substantia nigra dopaminergic neurons (projecting to dorsal striatum or accumbens) optogenetic stimulation as CS in Pavlovian and operant conditining of rats
  Saunders, B.T., Richard J.M., Margolis E.B., Janak P.H. - 2018

  DOPAMINE   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   CLASSICAL PAVLOVIAN CONDITIONING   SUBSTANTIA NIGRA   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   STRIATUM   NUCLEUS ACCUMBENS   OPERANT CONDITIONING
Contained in: Brain Res. Bull., 2018: 142, 320-327

Modulatory role of the intra-accumbal CB1 receptor in protein level of the c-fos and pCREB/CREB ration in the nucleus accumbens and ventral tegmental area in extinction and morphine seeking in the rats

Authors: Khaleghzadeh-Ahangar, H., Khodagholi F., Shaerzadeh F., Haghparast A.

  Intra-accumbal CB1 agonist or antagonist during conditioned place preference by morphine extinction on accumbal/ventral tegmental area CREB/c-fos expression during reinstatement phase in rats
  Khaleghzadeh-Ahangar, H., Khodagholi F., Shaerzadeh F., Haghparast A. - 2018

  CANNABINOIDS   PROTEINS AND GENES   NUCLEUS ACCUMBENS   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   EXTINCTION   OPIOIDS   CLASSICAL PAVLOVIAN CONDITIONING   RECALL AND RECONSOLIDATION
Contained in: Cell, 2018: 175, 34-35

A thalamic circuit lights up mood

Authors: Yanar, J., Halassa M.M.

  Thalamic perihabenular region and environmental light effects on animal behavior - Commentary
  Yanar, J., Halassa M.M. - 2018

  REVIEWS AND COMMENTARIES   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   CEREBRAL CORTEX   STRIATUM   NUCLEUS ACCUMBENS   LUMINANCE AND VISION   HYPOTHALAMUS
Contained in: Behav. Brain Res., 2018: 352, 94-98

Mild stress induces brain region-specific alterations of selective ER stress markers'mRNA expression in Wfs1-deficient mice

Authors: Altpere, A., Raud S., Sutt S., Reimets R., Visnapuu T., Toots M., Vasar E.

  Wfs-1 gene role in brain neuronal endoplasmic reticulum stress markers response to mild stress in mice
  Altpere, A., Raud S., Sutt S., Reimets R., Visnapuu T., Toots M., Vasar E. - 2018

  PROTEINS AND GENES   STRESS   HIPPOCAMPUS, FORNIX AND SUBICULUM   CEREBRAL CORTEX   EXPLORATORY ACTIVITY   NUCLEUS ACCUMBENS   STRIATUM   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION
Contained in: Eur. J. Neurosci., 2018: 48, 1924-1943

The circadian gene Nr1d1 in the mouse nucleus accumbens modulates sociability and anxiety-related behaviour

Authors: Zhao, C., Gammie S.C.

  Accumbal Nr1d1 gene role in spontaneous and conditioned social behavior, exploratory activity, response to stress and object place recogntion in male and female mice
  Zhao, C., Gammie S.C. - 2018

  NUCLEUS ACCUMBENS   CIRCADIAN RHYTHMS   ENVIRONMENT AND SOCIAL BEHAVIOR   CLASSICAL PAVLOVIAN CONDITIONING   DARK/LIGHT CONTEXT   EXPLORATORY ACTIVITY   STRESS   GENDER
Contained in: Eur. J. Neurosci., 2018: 48, 2182-2198

Positive reinforcement and c-fos expression following abuse-like thinner inhalation in mice: behavioural and immunohistochemical assessment

Authors: Malloul, H., Bennis M., Ba-M'hamed S.

  Paint thinner solvent inhalation on brain c-fos expression, locomotor activity and thinner inhalation related conditioned place preference in mice
  Malloul, H., Bennis M., Ba-M'hamed S. - 2018

  PROTEINS AND GENES   CLASSICAL PAVLOVIAN CONDITIONING   LOCOMOTOR ACTIVITY   CEREBRAL CORTEX   NUCLEUS ACCUMBENS   AMYGDALA   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   HIPPOCAMPUS, FORNIX AND SUBICULUM   SUBSTANTIA NIGRA
Contained in: Neurobiol. Learn. Mem., 2018: 154, 97-111

Metaplasticity at the addicted tetrapartite synapse: a common denominator of drug induced adaptations and potential treatment target for addiction

Authors: Neuhofer, D., Kalivas P.
Contained in: Neurobiol. Learn. Mem., 2018: 154, 87-96

The metaplastic effects of NMDA receptor blockade on reactivation of instrumental memories in rats

Authors: Piva, A., Gerace E., Di Chio M., Osanni L., Padovani L., Caffino L., Fumagalli F., Pellegrini-Giampietro D.E., Chiamulera C.

  Pre-tretrieval NMDA antagonist on appetitively extinguished operant responding accumbal/amygdalar zif268/glutamatergic/NMDA receptor expression related to trace reactivation in rats
  Piva, A., Gerace E., Di Chio M., Osanni L., Padovani L., Caffino L., Fumagalli F., Pellegrini-Giampietro D.E., Chiamulera C. - 2018

  N-METHYL-D-ASPARTATE (NMDA)   RECALL AND RECONSOLIDATION   OPERANT CONDITIONING   EXTINCTION   NUCLEUS ACCUMBENS   AMYGDALA   GLUTAMATE   PROTEINS AND GENES
Contained in: Neuropharmacology, 2018: 138, 57-71

Cooperative and dissociable involvement of the nucleus accumebns core and shell in the promotion and inhibition of actions during active and inhibitory avoidance

Authors: Piantadosi, P.T., Yeates D.C.M., Floresco S.B.

  Accumbens inactivation and systemic D-amphetamine on operant and inhibitory avoidance in rats
  Piantadosi, P.T., Yeates D.C.M., Floresco S.B. - 2018

  NUCLEUS ACCUMBENS   AVOIDANCE   OPERANT CONDITIONING   NEURAL REVERSIBLE INACTIVATIONS   DOPAMINE   NOCICEPTION   CONDITIONED AND UNCONDITIONED INHIBITION
Contained in: Neuropharmacology, 2018: 138, 245-256

Medium chian triglyceride diet reduces anxiety-like behaviors and enhances social competiveness in rats

Authors: Hollis, F., Mitchell E.S., Canto C., Wang D., Sandi C.

  Medium.chain triglycerides dietary implementation on prefrontal/accumbal mitochondrial function/protein levels, exploratory activity and social preference/interaction/aggressiveness in rats
  Hollis, F., Mitchell E.S., Canto C., Wang D., Sandi C. - 2018

  ENVIRONMENT AND SOCIAL BEHAVIOR   PROTEINS AND GENES   FEEDING AND DRINKING   EXPLORATORY ACTIVITY   STRESS   DARK/LIGHT CONTEXT   AGGRESSIVE AND DEFENSIVE BEHAVIOR   CEREBRAL CORTEX   GLUTAMATE   NUCLEUS ACCUMBENS
Contained in: Neuropharmacology, 2018: 139, 52-60

Chronic sleep restriction increases pain sensitivity over time in a periaquductal gray and nucleus accumebns dependent manner

Authors: Sardi, N.F., Lazzarim M.K., Guilhen V.A., Marcilio R.S., Natume P.S., Watanabe T.C., Lima M.M.S., Tobaldini G., Fischer L.

  Periaqueductal gray and accumbal role in sleep deprivation effects on nociception in rats: NMDA lesions and c-fos expression study
  Sardi, N.F., Lazzarim M.K., Guilhen V.A., Marcilio R.S., Natume P.S., Watanabe T.C., Lima M.M.S., Tobaldini G., Fischer L. - 2018

  SLEEP   NOCICEPTION   NUCLEUS ACCUMBENS   CENTRAL NERVOUS SYSTEM LESIONS   PROTEINS AND GENES
Contained in: Neuropharmacology, 2018: 139, 68-75

Chronic stress dysregulates amygdalar output to the prefrontal cortex

Authors: Lowery-Gionta, E.G., Crowley N.A., Bukalo O., Silverstein S., Holmes A., Kash T.L.

  Stress on prefrontal, basolateral amygdalar, accumbal and bedi nucleus of the stria terminalis neuron excitability and exploratory activity in mice of different strain
  Lowery-Gionta, E.G., Crowley N.A., Bukalo O., Silverstein S., Holmes A., Kash T.L. - 2018

  STRESS   AMYGDALA   CEREBRAL CORTEX   NUCLEUS ACCUMBENS   GLUTAMATE   STRAIN   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   EXPLORATORY ACTIVITY
Contained in: Neuropharmacology, 2018: 139, 26-40

Exposure to environmental enrichment attenuates addiction-like behavior and alters molecular effects of heroin self-administration in rats

Authors: Imperio, C.G., McFalls A.J., Hadad N., Blanco-Berdugo L., Masser D.R., Colechio E.M., Coffey A.A., Bixler G.V., Stanford D.R., Vrana K.E., Grigson P.S., Freeman W.M.

  Environmental enrichment exposure on heroin operant self-administration acquisition , extinction, reinstatement and related prefrontal/ventral striatal early gene/DNA methylation levels in rats
  Imperio, C.G., McFalls A.J., Hadad N., Blanco-Berdugo L., Masser D.R., Colechio E.M., Coffey A.A., Bixler G.V., Stanford D.R., Vrana K.E., Grigson P.S., Freeman W.M. - 2018

  ENVIRONMENT AND SOCIAL BEHAVIOR   OPIOIDS   OPERANT CONDITIONING   PROTEINS AND GENES   EXTINCTION   RECALL AND RECONSOLIDATION   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   NUCLEUS ACCUMBENS   CEREBRAL CORTEX
Contained in: Neuropharmacology, 2018: 139, 117-123

Thioredoxin-1 downregulation in the nucleus accumebnes promotes methamphetamine-primed reinstatement in mice

Authors: Huang, M., Yan C., Yang X., Zhou X., Lv W., Guo N., Li Y., Bai J.

  Accumbal thioredoxin-1 role in conditioned place preference by methamphetamine reinstatement and related local GluN2b/ERK/CREB expression in mice
  Huang, M., Yan C., Yang X., Zhou X., Lv W., Guo N., Li Y., Bai J. - 2018

  NUCLEUS ACCUMBENS   DOPAMINE   RECALL AND RECONSOLIDATION   CLASSICAL PAVLOVIAN CONDITIONING   PROTEINS AND GENES   N-METHYL-D-ASPARTATE (NMDA)   PROTEIN KINASES   EXTINCTION
Contained in: Neuropharmacology, 2018: 140, 25-34

Maternal methamphetamine exposure causes cognitive impairment and alteration of neurodevelopment-related genes in adult offspring mice

Authors: Dong, N., Zhu J., Han W., Wang S., Yan Z., Ma D., Goh E.L.K., Chen T.

  Methamphetamine maternal exposure on neurodevelopment related gene expression, object recognition and Morris water maze performance in male and female mouse offspring
  Dong, N., Zhu J., Han W., Wang S., Yan Z., Ma D., Goh E.L.K., Chen T. - 2018

  DOPAMINE   PROTEINS AND GENES   HIPPOCAMPUS, FORNIX AND SUBICULUM   NUCLEUS ACCUMBENS   SPATIAL ORIENTATION AND SPATIAL MEMORY   GENDER   NEUROGENESIS AND PLASTICITY
Contained in: Pharmacol. Biochem. Behav., 2018: 174, 23-32

Viral vector strategies for investigating midbrain dopamine circuits underlying motivated behaviors

Authors: Pinto, D.F.C., Lammel S.

  Viral vector strategies and optogenetic manipulation of midbrain dopamine neurons - Review
  Pinto, D.F.C., Lammel S. - 2018

  REVIEWS AND COMMENTARIES   DOPAMINE   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   PROTEINS AND GENES   NUCLEUS ACCUMBENS   HYPOTHALAMUS   SUBSTANTIA NIGRA   DORSAL AND MEDIAL RAPHE NUCLEI   CEREBRAL CORTEX
Contained in: Pharmacol. Biochem. Behav., 2018: 174, 33-41

Viral strategies for targeting cortical circuits that control cocaine-taking and cocaine-seeking in rodents

Authors: Garcia, A.F., Nakata K.G., Ferguson S.M.

  Prefrontal cortex circuit viral optogenetic/chemogenetic trageting related to cocaine addiction in rodents - Review
  Garcia, A.F., Nakata K.G., Ferguson S.M. - 2018

  REVIEWS AND COMMENTARIES   CEREBRAL CORTEX   DOPAMINE   NUCLEUS ACCUMBENS   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   AMYGDALA   PROTEINS AND GENES
Contained in: Pharmacol. Biochem. Behav., 2018: 174, 42-52

Circuit-based frameworks of depressive behaviors: the role of reward circuitry and beyond

Authors: Knowland, D., Lim B.K.

  Brain circuit involved in depressive-like behaviors: animal model studies - Review
  Knowland, D., Lim B.K. - 2018

  REVIEWS AND COMMENTARIES   ENVIRONMENT AND SOCIAL BEHAVIOR   STRESS   AGGRESSIVE AND DEFENSIVE BEHAVIOR   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   DOPAMINE   NUCLEUS ACCUMBENS   CEREBRAL CORTEX   AMYGDALA   HIPPOCAMPUS, FORNIX AND SUBICULUM   STRIATUM
Contained in: Pharmacol. Biochem. Behav., 2018: 174, 53-63

Neural systems mediating the inhibition of cocaine-seeking behaviors

Authors: Ewald, V.A.M., LaLumiere R.T.

  Brain circuit chemogenetic/optogenetic viral vector targeting in cocaine addiction animal model studies - Review
  Ewald, V.A.M., LaLumiere R.T. - 2018

  REVIEWS AND COMMENTARIES   DOPAMINE   CEREBRAL CORTEX   OPERANT CONDITIONING   CLASSICAL PAVLOVIAN CONDITIONING   EXTINCTION   RECALL AND RECONSOLIDATION   NUCLEUS ACCUMBENS   HYPOTHALAMUS   HIPPOCAMPUS, FORNIX AND SUBICULUM
Contained in: Proc. Natl. Acad. Sci. USA, 2018: 115, E9479-E9488

GIRK currents in VTA dopamine neurons control the sensitivity of mice to cocaine-induced locomotor sensitization

Authors: Rifkin, R.A., Huyghe D., Li X., Parakala M., Aisenberg E., Moss S.J., Slesinger P.A.

  GIRK potassium channel role in ventral tegmental area and substantia nigra dopaminergic neuron excitability and related locomotor sensitization to cocaine exposure in mice
  Rifkin, R.A., Huyghe D., Li X., Parakala M., Aisenberg E., Moss S.J., Slesinger P.A. - 2018

  UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   DOPAMINE   SUBSTANTIA NIGRA   PROTEINS AND GENES   STRIATUM   NUCLEUS ACCUMBENS   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   LOCOMOTOR ACTIVITY
Contained in: Science, 2018: 362, 429-434

the paraventricular thalamus is a critical thalamic area for wakefulness

Authors: Ren, S., Wang Y., Yue F., Cheng X., Dang R., Qiao Q., Sun X., Li X., Jiang Q., Yao J., Qin H., Wang G., Liao X., Gao D., Xia J., Zhang J., Hu B., Yan J., Wang Y., Xu M., Han Y., Tang X., Chen X., He C., Hu Z.

  Lateral hypothalamus-paraventricular thalamus-accumbens projection role in wakefulness in mice: optogenetic study
  Ren, S., Wang Y., Yue F., Cheng X., Dang R., Qiao Q., Sun X., Li X., Jiang Q., Yao J., Qin H., Wang G., Liao X., Gao D., Xia J., Zhang J., Hu B., Yan J., Wang Y., Xu M., Han Y., Tang X., Chen X., He C., Hu Z. - 2018

  UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   GLUTAMATE   ANESTHESIA   PROTEINS AND GENES   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   CEREBRAL CORTEX   SLEEP   NUCLEUS ACCUMBENS   HYPOTHALAMUS
Contained in: Neurosci. Lett., 2018: 686, 133-139

Memantine attentuated alcohol withdrawal-induced anxiety-like behaviors through down-regulating NR1-CaMKII-ERK signaling pathway

Authors: Yuanyuan, J., Junyan Z., Cuola D., Jingjing C., Yuhui S., Dan X., Wei D., Yongsheng Z.

  Systemic NMDA antagonist mementine on ethanol withdrawal effects on prefrontal/accumbal NR1-CaMKII-ERK pathway expression and locomotion/exploration in rats
  Yuanyuan, J., Junyan Z., Cuola D., Jingjing C., Yuhui S., Dan X., Wei D., Yongsheng Z. - 2018

  N-METHYL-D-ASPARTATE (NMDA)   PROTEIN KINASES   EXPLORATORY ACTIVITY   CEREBRAL CORTEX   NUCLEUS ACCUMBENS   RECALL AND RECONSOLIDATION   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY
Contained in: Neurosci. Lett., 2018: 686, 168-174

Acute morphine adminbistration alters the power of local field potentials in mesolimbic pathway of freely moving rats: involvement of dopamine receptors

Authors: Soleimani, S.M.A., Mohamadi M.A.H. M.H., Raoufy M.R., Azizi H., Nasehi M., Zarrindast M.R.

  D1/D2 receptor modulation on morphine exposure effects on ventral tegmental area/accumbal local field potential frequency in rats
  Soleimani, S.M.A., Mohamadi M.A.H. M.H., Raoufy M.R., Azizi H., Nasehi M., Zarrindast M.R. - 2018

  OPIOIDS   DOPAMINE   NUCLEUS ACCUMBENS   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION