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2018
A brain boost to fight Alzheimer's disease
Authors: Spires-Jones, T.L., Ritchie C.W. Exercise on hippocampal neurogenesis/plasticity/brain-derived neurotrophic factor levels and brain neuroprotection - Commentary
Spires-Jones, T.L., Ritchie C.W. - 2018
Effects of vortioxetine and fluoxetine on the level of brain derived neurotrophic factors (BDNF) in the hippocampus of chronic unpredictable midl stress-induced depressive rats
Authors: Lu, Y., Ho C.S., McIntyre R.S., Wang W., Ho R.C. Phosphodiesterase inhibitor roflumilast on object location, verbal learning task performance and related cortical event-related potential in young adult humans
Van Duinen, M.A., Sambeth A., Heckman P.R.A., Smit S., Tsai M., Lahu G., Uz T., Blokland A., Prickaerts J. - 2018
Vartioxetine and fluoxetine on stress effects on hippocampal neuronal damage/brain-derived neurotrophic factor expression, grooming/rearing behavior and sucrose preference in rats
Lu, Y., Ho C.S., McIntyre R.S., Wang W., Ho R.C. - 2018
Neural circuitry among connecting the hippocampus, prefrontal cortex and basolateral amygdala in a mouse depression model: associations correlations between BDNF levels and BOLD-fMRI signals
Authors: Huang, P., Gao T., Dong Z., Zhou C., Lai Y., Pan T., Liu Y., Zhao X., Sun X., Hua H., Wen G., Gao L., Lv Z. Chronic mild stress effects on brain activation and c-fos/brain-derived neurotrohic factor expression, sucrose preference and response to stress in mice
Huang, P., Gao T., Dong Z., Zhou C., Lai Y., Pan T., Liu Y., Zhao X., Sun X., Hua H., Wen G., Gao L., Lv Z. - 2018
Deletion of asparagine endopeptidase reduces anxiety- and depressive-like behaviors and improves abilities of spatial cognition in mice
Authors: Gao, J., Li K., Du L., Yin H., Tan X., Yang Z. Asparagine endopeptidase role in hippocampal neuron excitability/brain-derived neurotrophic factor-synaptic proteins levels, locomotion, exploration, response to stress and Morris water maze performance in mice
Gao, J., Li K., Du L., Yin H., Tan X., Yang Z. - 2018
The memory-enhancing effects of 7,8,4'-trihydroxyisoflavone, a major metbolite of daidzein, are associated with activation of the cholinergic system and BDNF signbaling pathway in mice
Authors: Ko, Y.-H., Kwon S.-H., Ma S.-X., Seo J.-Y., Lee B.-R., Kim K., Kim S.Y., Lee S.-Y., Jang C.-G. Daidzein isoflavone metabolite on hippocampal brain-derived neurotrophic factor/CREB/extracellular-signal regulated kinase expression, nociception, spatial learning, passive avoidance and scopolamine-induced cognitive and cholinergic system deficit in mice
Ko, Y.-H., Kwon S.-H., Ma S.-X., Seo J.-Y., Lee B.-R., Kim K., Kim S.Y., Lee S.-Y., Jang C.-G. - 2018
Behavioral phenotypes and neurobiological mechanisms in the Shank1 mouse model for autism spectrum disorder: a translational perspective
Authors: Sungur, A.O., Schwarting R.K.W., Wohr M. Shank1 autism spectrum disorder mouse model - Review
Sungur, A.O., Schwarting R.K.W., Wohr M. - 2018
Depressive-and anxiety-like phenotypes in young adult APPSwe/PS1dE9 transgenic mice with insensitivity to chronic mild stress
Authors: Gao, J.-Y., Chen Y., Su D.-Y., Marshall C., Xiao M. Chronic mild stress effects on serum corticosterone level, hippocampal CREB/brain-derived neurotrophic factor/neuroinflammation markers expressiom, social interaction, locomotion/exploration, sucrose preference, response to stress and spatial learning in APP and control mice
Gao, J.-Y., Chen Y., Su D.-Y., Marshall C., Xiao M. - 2018
Effects of advanced maternal age on cognitive and emotional development in offspring rats
Authors: Han, W., Dong X., Song X., Cheng L., Xie L., Chen H., Jiang L. Maternal age on hippocampal morphology, CREB/brain-derived neutorophic factor expression, exploratory activity and spatial learning in offspring rats
Han, W., Dong X., Song X., Cheng L., Xie L., Chen H., Jiang L. - 2018
Premature hippocampus-dependent memory decline in middle-aged females of a genetic rat model of depression
Authors: Lim, P.H., Wert S.L., Tunc-Ozcan E., Marr R., Ferreira A., Redei E.E. Hippocampal/prefrontal/amygdalar insulin-like growth factor 1/2 expression and fear conditioning performance in female rats of different age and strain
Lim, P.H., Wert S.L., Tunc-Ozcan E., Marr R., Ferreira A., Redei E.E. - 2018
Metaplasticity within the spinal cord: evidence brain-derived neurotrophic factor (BDNF), tumor necrosis factor (TNF), and alterations in GABA function (ionic plasticity) modulate pain and the capacity to learn
Authors: Grau, J.W., Huang Y.-J. Spinal cord plasticity - Review
Grau, J.W., Huang Y.-J. - 2018
Intermittent fasting promotes prolonged associative interactions during synaptic tagging/capture by altering the metaplastic properties of the CA1 hippocampal neurons
Authors: Dasgupta, A., Kim J., Manakkadan A., Arumugam T.V., Sajikumar S. Dietary regimen on hippocampal neuron excitability/plasticity/brain-derived neurotrophic factor expression in mice
Dasgupta, A., Kim J., Manakkadan A., Arumugam T.V., Sajikumar S. - 2018
The BDNF Val66Met prodomain disassembles dendritic spines altering fear extinction circuitry and behavior
Authors: Giza, J.I., Kim J., Meyer H.C., Anastasia A., Dincheva I., Zheng C.I., Lopez K., Bains H., Yang J., Bracken C., Liston C., Jing D., Hempstead B.L: Brain-derived neurotrophic role in hippocampal.prelimbic projection neuron plasticity, fear conditioning acquisition and extinction in mice of different age
Giza, J.I., Kim J., Meyer H.C., Anastasia A., Dincheva I., Zheng C.I., Lopez K., Bains H., Yang J., Bracken C., Liston C., Jing D., Hempstead B.L: - 2018
Roflumilast promotes memory recovery and attenuates white matter injury in aged rats subjected to chronic cerebral hypoperfusion
Authors: Santiago A., Soares L.M., Schepers M., Milani H., Vanmierlo T., Prickaerts J., de Oliveira R.M.W. Phosphodiesterase type 4 inhibitor roflumilast exposure on chronic cerebral hypoperfusion effects on white matter injury, hippocampal neuroinflammation, CREB-brain-derived neurotrophic factor expression and spatial navigation in aged rats
Santiago A., Soares L.M., Schepers M., Milani H., Vanmierlo T., Prickaerts J., de Oliveira R.M.W. - 2018
BDNF and TrkB mediate the improvement from chronic stress-induced spatial memory deficits and CA3 dendritic retraction
Authors: Ortiz, J.B., Anglin J.M., Daas E.J., Paode P.R., Nishimura K., Conrad C.D. Brain-derived neurotrophic factor role in stress effects on hippocampal neuron plasticity and spatial learning performance in rats
Ortiz, J.B., Anglin J.M., Daas E.J., Paode P.R., Nishimura K., Conrad C.D. - 2018
Sulforaphane alleviates lipopolysaccharide-induced spatial learning and memory dysfunction in mice: the role of BDNF-mTOR signaling pathway
Authors: Gao, J., Xiong B., Zhang B., Li S., Huang N., Zhan G., Jiang R., Yang L., Wu Y., Miao L., Zhu B., Yang C., Luo A. Sulforaphane exposure on lipolysaccharide injection effects on hippocampal neuroinflammation/brain-derived neurotrophic factor-synaptic protein levels spatial learning performance in mice: BDNF-mTOR signaling pathway study
Gao, J., Xiong B., Zhang B., Li S., Huang N., Zhan G., Jiang R., Yang L., Wu Y., Miao L., Zhu B., Yang C., Luo A. - 2018
Aberrant amygdala-dependent fear memory in corticosterone-treated mice
Authors: Inagaki, R., Moriguchi S., Fukunaga K. Corticosterone exposure on basolateral amygdala c-fos/BDNF/CREB/ERK expression, neuron excitability-plasticity, exploratory activity and fear conditioning in mice
Inagaki, R., Moriguchi S., Fukunaga K. - 2018
Ouabain increases neuronal branching in hippocampus and improves spatial memory
Authors: Orellana, A.M., Leite J.A., Kinoshita P.F., Vasconcelos A.R., Andreotti D.Z., de Sà Lima L., Xavier G.F., Kawamoto E.M., Scavone C. Intra-hippocampal ouabain on neuron plastiity/CREB-BDNF expression and Morris water maze performance in rats
Orellana, A.M., Leite J.A., Kinoshita P.F., Vasconcelos A.R., Andreotti D.Z., de Sà Lima L., Xavier G.F., Kawamoto E.M., Scavone C. - 2018
The effect of bilateral low-frequency rTMS over dorsolateral prefrontal cortex on serum brain-derived neurotropic factor and serotonin in patients with generalized anxiety disorder
Authors: Lu, R., Zhang C., Liu Y., Wang L., Chen X., Zhou X. Dorsolateral prefrontal cortex transcranial magnetic stimulation on serum BDNF/serotonin levels in anxiety disorder humans
Lu, R., Zhang C., Liu Y., Wang L., Chen X., Zhou X. - 2018
Childhood trauma and emotion regulation: the moderator role of BDNF Val66Met
Authors: Bilc, M.I., Vulturar R., Chis A., Buciuman M., Nutu D., Bunea I., Szentagotai-Tatar A., Miu A.C. BDNF Val66Met gene role in childhood trauma emotional reapprasail in humans
Bilc, M.I., Vulturar R., Chis A., Buciuman M., Nutu D., Bunea I., Szentagotai-Tatar A., Miu A.C. - 2018
Exercise and low-level GABAA receptor inhibition modulate locomotor activity and the expression of BDNF accompanied by changes in epigenetic regulation in the hippocampus
Authors: Maejima, H., Nimuna S., Okuda A., Inoue T., Hayashi M. Aerobic exercise and GABA-A antagonist exposure on hippocampal BDNF/histone acetyltranspherase-deacetylase levels, locomotor activity and object recognition in mice
Maejima, H., Nimuna S., Okuda A., Inoue T., Hayashi M. - 2018
Postnatal TrkB ablation in corticolimbic interneurons induces social dominance in male mice
Authors: Tan, S., Xiao Y., Yin H.H., Chen A.I. Soong T.W., Je H.S. BDNF/TrkB signaling from prefrontal inhibitory GABA-ergic interneurons on social dominance behavior in male mice: optogenetic manipulation study
Tan, S., Xiao Y., Yin H.H., Chen A.I. Soong T.W., Je H.S. - 2018
The effect of NAD-299 and TCB-2 on learning and memory, hippocampal BDNF levels and amyloid plaques in Streptozotocin-induced memory deficits in male rats
Authors: Afshar, S., Shahidi S., Rohani A.H., Komaki A., Asl S.S. 5-HT1A antagonist and 5-HT2A agonist on intracerebroventricular streptozotocin effects on hippocampal BDNF levels, hippocampal/cortical neuronal damage, locomotor activity, object recognition and passive avoidance in rats
Afshar, S., Shahidi S., Rohani A.H., Komaki A., Asl S.S. - 2018
Impairment in exploratory behavior is associated with arc gene overexpresion in the dorsolateral striatum of rats with nigral injection of L-buthionine sulfoximine
Authors: Diaz-Hung, M.L., Ruiz-Fuentes J.L., Diaz-Garcia A., Leon-Martinez R., Alberti-Amafor E., Pavon-Fuentes N., Blanco-Lezcano L. Intra-substantia nigra y-glutamylcysteine synthase inhibitor on local and dorsolateral striatal Arc/brain-derived neurotrophic factor expression, locomotion/exploration and object recognition in rats
Diaz-Hung, M.L., Ruiz-Fuentes J.L., Diaz-Garcia A., Leon-Martinez R., Alberti-Amafor E., Pavon-Fuentes N., Blanco-Lezcano L. - 2018
The effects of donepezil on phencyclidine-induced cignitive deficits in a mouse model of schizophrenia
Authors: Li, Y.-X., Ye Z.-H., Chen T., Jia X.-F., He L. Donepezil on phencyclidine exposure effects on cortical/hippocampal BDNF/NGF/protein levels, passive avoidance and Morris water maze performance in mice
Li, Y.-X., Ye Z.-H., Chen T., Jia X.-F., He L. - 2018
Towards combinational approaches for preserving cognitive fitness in aging
Authors: Brem, A.-K., Sensi S.L. Aging-related cognitive decline preserving - Review
Brem, A.-K., Sensi S.L. - 2018
NMDA receptors and BDNF are necessary for discrimination of overlapping spatial and non-spatial memories in perirhinal cortex and hippocampus
Authors: Miranda, M., Kent B.A., Morici J.F., Gallo F., Saksida L.M., Bussey T.J., Weisstaub N., Bekinschtein P. Hippocampal and perirhinal NMDA and BDNF receptor role in spatial discrimination acquisition and consolidation in rats
Miranda, M., Kent B.A., Morici J.F., Gallo F., Saksida L.M., Bussey T.J., Weisstaub N., Bekinschtein P. - 2018
The impact of chronic fluoxetine on conditioned fear expression and hippocampal FGF2 in rats: short- and long-term effects
Authors: Graham, B.M., Dong V., Richardson R. Fluoxetine exposure on hippocampal FGF2 growth factor expression and fear conditioning response in naturally expressing low- and high-fear rats
Graham, B.M., Dong V., Richardson R. - 2018
Postnatal exposure to poly (I:C) impairs learning and memory trough changes in synaptic plasticity gene expression in developing rat brain
Authors: Baghel, M.S., Singh B., DhuriyaY.K., Shukla R.K., Patro N., Khanna V.K., Patro I.K., Thakur M.K. Post-natal poly (I:C) immune activation on hippocampal/frontal cortex Arc/ERG1/BDNF expression, passive avoidance and Morris water maze performance in ypung and adult rats
Baghel, M.S., Singh B., DhuriyaY.K., Shukla R.K., Patro N., Khanna V.K., Patro I.K., Thakur M.K. - 2018
Resveratrol and dimethyl fumarate ameliorate depression-like behaviour in a rat model of chronic unpredictable midl stress
Authors: El-Fattah, A.A.A., Fahim A.T., Sadik N.A.H., Ali B.M. Antioxidants resveratrol and dimethyl fumrate exposure on chronic stress effects on hippocampal oxidative stress/serotonin/brain-derived neurotrophic factor levels, serum corticosterone levels, sucrose preference and response to stress in rats
El-Fattah, A.A.A., Fahim A.T., Sadik N.A.H., Ali B.M. - 2018
Activity-regulated transcription: bridging the gap between neural activity and behavior
Authors: Yap, E.-L., Greenberg M.E. Neuronal activity, early gene induction and animal behavior - Review
Yap, E.-L., Greenberg M.E. - 2018