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2015
The effects of chronic fluoxetine treatment following injury of medial frontal cortex in mice
Authors: McAllister, B.B., Spanswick S.C., Patel P.P., Barneto A.A., Dyck R.H. Fluoxetine on medial frontal cortex injury effects on locomotion/exploration, spatial learning, cortical neuroplasticity and hippocampal neurogenesis in mice
McAllister, B.B., Spanswick S.C., Patel P.P., Barneto A.A., Dyck R.H. - 2015
Repeated social defeat stress enhances the anxiogenic effect of bright light on operant reward-seeking behavior in rats
Authors: Jaisinghani, S., Rosenkranz J.A. Social stress and luminescence on operant appetitive conditioning, social interactions and exploratory activity in rats
Jaisinghani, S., Rosenkranz J.A. - 2015
The possible relationship between expressions of TRPC3/5 channels and cognitive changes in rat model of chronic unpredictable stress
Authors: Qin, X., Liu Y., Zhu M., Yang Z. Stress effects on sucrose preference, exploratory activity, social learning and hippocampal long-term potentition and TRPC3/5 receptor expression/plasticity in rats
Qin, X., Liu Y., Zhu M., Yang Z. - 2015
Long-term cognitive dysfunction in the rat following docetaxel treatment is ameliorated by the phosphodiesterase-4 inhibitor, rolipram
Authors: Callaghan, C.K., O'Mara S.M. Rolipram on chemotherapic docetaxel effects on exploratory activity, response to stress and object recognition in rats
Callaghan, C.K., O'Mara S.M. - 2015
BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice
Authors: Korb, E., Herre M., Zucker-Scharff I., Darnell R.B., Allis C.D. Bromodomain and extra-terminal domain protein Brd4 role in transcription, exploratory activity, fear conditioning and object recognition in mice
Korb, E., Herre M., Zucker-Scharff I., Darnell R.B., Allis C.D. - 2015
Ceftriaxone prevents and reverses behavioral and neuronal deficits in and MPTP-induced animal model of Parkinson's disease dementia
Authors: Hsu, C.-Y., Hung C.-S., Chang H.-M., Liao W.-C., Ho S.-C., Ho Y.-J. Nigral/striatal dopaminergic lesions on exploratory activity, spatial learning and object recognition in rats: glutamate transporter 1 ceftriaxone effects
Hsu, C.-Y., Hung C.-S., Chang H.-M., Liao W.-C., Ho S.-C., Ho Y.-J. - 2015
Fluoxetine treatment reverses the intergenerational impact of maternal separation on fear and anxiety behaviors
Authors: Xiong, G.-J., Yang Y., Cao J., Mao R.-R., Xu L: Fluoxetine on maternal sepration effects on exploratory activity, Morris water maze performance and fear conditioning acquisition and extinction in male and female rat offspring: effects on second generation
Xiong, G.-J., Yang Y., Cao J., Mao R.-R., Xu L: - 2015
Relationships between diet-related changes in the gut microbiome and cognitive flexibility
Authors: Magnusson, K.R., Hauck L., Jeffrey B.M., Elias V., Humphrey A., Nath R., Perrone A., Bermudez L.E. Normal high fat or high sucrose diet on exploratory activity, Morris water maze and object recognition in mice: gut microbiome analysis
Magnusson, K.R., Hauck L., Jeffrey B.M., Elias V., Humphrey A., Nath R., Perrone A., Bermudez L.E. - 2015
Functional characterization of the PCLO p.Ser4814Ala variant associated with major depressive disorder reveals cellular but not behavioral differences
Authors: Giniatullina, A., Maroteaux G., Geerts C.J., Koopmans B., Loos M., Klaassen R., Chen N., Van Der Schors R.C., Van Nierop P., Li K.W., De Jong J., Altrock W.D., Cornelisse L.N., Toonen R.F., Van Der Sluis S., Sullivan P.F., Stiedl O., Posthuma D., Smit A.B., Groffen A.J., Verhage M. pSer4814Ala protein on hippocampal plasticity, circadian locomotor activity, response to stress, neophobia, exploratory activity, prepulse inhibition of startle reflex and cognitive task performance in mice
Giniatullina, A., Maroteaux G., Geerts C.J., Koopmans B., Loos M., Klaassen R., Chen N., Van Der Schors R.C., Van Nierop P., Li K.W., De Jong J., Altrock W.D., Cornelisse L.N., Toonen R.F., Van Der Sluis S., Sullivan P.F., Stiedl O., Posthuma D., Smit A.B., Groffen A.J., Verhage M. - 2015
Theta frequency prefrontal-hippocampal driving relationship during free exploration in mice
Authors: Zhan, Y. Prefrontal and hippocampal theta firing on social interaction and exploratory activity in mice
Zhan, Y. - 2015
The nonsteroidal antiinflammatory drug piroxicam reverses the onset of depressive-like behavior in 6-OHDA animal model of Parkinson's disease
Authors: Santiago, R.M., Tonin F.S., Barbiero J., Zaminelli T., Boschen S.L., Andreatini R., Da Cunha C., Lima M.M.S., Vital M.A.B.F. Intra-substantia nigra 6-hydroxydopamine on locomotion/exploration, response to stress and hippocampal/striatal dopamine/serotonin levels in rats
Santiago, R.M., Tonin F.S., Barbiero J., Zaminelli T., Boschen S.L., Andreatini R., Da Cunha C., Lima M.M.S., Vital M.A.B.F. - 2015
Concurrent maternal and pup postnatal tobacco smoke exposure in Wistar rats changes food preference and dopaminergic reward system parameters in the adult male offsprings
Authors: Pinheiro, C.R., Moura E.G., Manhaes A.C., Fraga M.C., Claudio-Neto S., Abreu-Villaca Y., Oliveira E., Lisboa P.C. Prenatal and postnatal tobacco smoke exposure on food preference and dopaminergic stratial/accumbal/tegmental system expression in adult rats
Pinheiro, C.R., Moura E.G., Manhaes A.C., Fraga M.C., Claudio-Neto S., Abreu-Villaca Y., Oliveira E., Lisboa P.C. - 2015
Preventive effects of ginsenoside Rg1 on post-traumatic stress disorder (PTSD)-like behavior in male C57/B6 mice
Authors: Wang, Z., Zhu K., Chen L., Yang L.O., Huang Y., Zhao Y. Ginsenoside Rg1 on stress effects on exploratory activity and corticotropin-releasing hormone/corticosterone blood levels in mice
Wang, Z., Zhu K., Chen L., Yang L.O., Huang Y., Zhao Y. - 2015
Effects of enviornmental enrichment during induction of methamphetamine dependence on the behavioral withdrawal symptoms in rats
Authors: Hajheidari, S., Miladi-gorji H., Bigdeli I. Environmental enrichment on methamphetamine effects on response to stress and exploratory activity in rats
Hajheidari, S., Miladi-gorji H., Bigdeli I. - 2015
Brief fear preexposure facilitates subsequent fear conditioning
Authors: Iwasaki, S., Sakaguchi T., Ikegaya Y. Footshock pre-exposure and stress on fear conditioning acquisition in mice: MK-801 effects
Iwasaki, S., Sakaguchi T., Ikegaya Y. - 2015
Cognitive impairment and morphological changes in the dorsal hippocampus of very old female rats
Authors: Morel, G.R., Andersen T., Pardo J., Zuccolilli G.O., Cambiaggi V.L., Herenu C.B., Goya R.G. Hippocampal neuron degeneration, exploratory activity and spatial learning in female rats of different age
Morel, G.R., Andersen T., Pardo J., Zuccolilli G.O., Cambiaggi V.L., Herenu C.B., Goya R.G. - 2015
Chronic maternal hyperglycemia induced during mid-pregnancy in rats increases rage expression, augments hippocampal excitability, and alters behavior of the offspring
Authors: Chandna, A.R., Kuhlmann N., Bryce C.A., Greba Q., Campanucci V.A., Howland J.G. Chronic maternal hyperglicemia on RAGE protein expression, hippocampal neuron excitability, exploratory activity, prepulse inhibition of startle reflex, operant conditioning and object recognition in rat offspring
Chandna, A.R., Kuhlmann N., Bryce C.A., Greba Q., Campanucci V.A., Howland J.G. - 2015
Anxiogenic drugs administration and elevated plus-maze exposure in rats activate populations of relaxin-3 neurons in the nucleus incertus and serotonergic neurons in the dorsal raphe nucleus
Authors: Lawther, A.J., Clissold M.L., Ma S., Kent S., Lowry C.A., Gundlach A.L., Hale M.W. Exploratory activity and anxiogenic drugs administration on nucleus incertus and dorsal raphe nuclei c-fos expression in rats
Lawther, A.J., Clissold M.L., Ma S., Kent S., Lowry C.A., Gundlach A.L., Hale M.W. - 2015
Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice
Authors: Kemppainen, S., Lindholm P., Galli E., Lahtinen H.-M., Koivisto H., Hamalainen E., Saarma M., Tanila H. Intra-hippocampal cerebral dopamine neurotrophic factor (CDNF) on exploratory activity, Morris water maze and object recognition in 12-month-old APP/PSL and control mice
Kemppainen, S., Lindholm P., Galli E., Lahtinen H.-M., Koivisto H., Hamalainen E., Saarma M., Tanila H. - 2015
Neuroanatomical and behavioral deficits in mice haploinsufficient for Pericentriolar material 1 (Pcm1)
Authors: Zoubovsky, S., Oh E.C., Cash-Padgett T., Johnson A.W., Hou Z., Mori S., Gallagher M., Katsanis N., Sawa A., Jaaro-Peled H. Pericentriolar material 1 protein on locomotion/exploration, prepulse inhibition of startle reflex and social interaction in mice
Zoubovsky, S., Oh E.C., Cash-Padgett T., Johnson A.W., Hou Z., Mori S., Gallagher M., Katsanis N., Sawa A., Jaaro-Peled H. - 2015
Acute restraint stress and corticosterone transiently disrupts novelty preference in an object recognition task
Authors: Vargas-Lopez, V., Torres-Berrio A., Gonzalez-Martinez L., Munera A., Lamprea M.R. Stress and corticosterone administration on locomotion/exploration and object recognition in rats
Vargas-Lopez, V., Torres-Berrio A., Gonzalez-Martinez L., Munera A., Lamprea M.R. - 2015
Endocannabinoid-mediated improvement on a test of aversive memory in a mouse model of fragile X syndrome
Authors: Qin, M., Zeidler Z., Moulton K., Krych L., Xia Z., Smith C.B. Fatty acid amide hydrolase inhibitor propofol on fragile X mental retardation protein absence effects on exploratory activity, social interaction and passive avoidance in mice: GABA-A and CB1 receptor modulation
Qin, M., Zeidler Z., Moulton K., Krych L., Xia Z., Smith C.B. - 2015
Opposite roles for neuropeptide S in the nucleus accumbens and bed nucleus of the stria terminalis in learned helplessness rats
Authors: Shirayama, Y., Ishima T., Oda Y., Okamura N., Iyo M., Hashimoto K. Intra-nucleus accumbens or bed nucleus of the stria terminalis neuropeptide S on "learned helplessness" in rats: effects on exploratory activity, passive and active avoidance
Shirayama, Y., Ishima T., Oda Y., Okamura N., Iyo M., Hashimoto K. - 2015
Overexpression of the type 1 adenylyl ciclase in the forebrain leads to deficits of behavioral inhibition
Authors: Chen, X., Cao H., Saraf A., Zweifel L.S., Storm D.R. Adenylyl cyclase type 1 role in locomotion/exploration, social behavior, response to stress, neophobia and prepulse inhibition of startle reflex in mice
Chen, X., Cao H., Saraf A., Zweifel L.S., Storm D.R. - 2015
The recognition of a novel-object in a novel context leads to hippocampal and parahippocampal c-Fos involvement
Authors: Arias, N., Mendez M., Arias J.L. Novel object/place recognition on hippocampal and parahippocampal cortex c-fos expression in rats
Arias, N., Mendez M., Arias J.L. - 2015
Central relaxin-3 receptor (RXFP3) activation reduces elevated, but not basal, anxiety-like behaviour in C57BL/6J mice
Authors: Zhang, C., Chua B.E., Yang A., Shabanpoor F., Hossain M.A., Wade J.D., Rosengren K.J., Smith C.M., Gundlach A.L. Brain relaxin-3 receptor role in exploratory activity and anxiety in mice
Zhang, C., Chua B.E., Yang A., Shabanpoor F., Hossain M.A., Wade J.D., Rosengren K.J., Smith C.M., Gundlach A.L. - 2015
Doxorubicin and cyclophosphamide induce cognitive dysfunction and activate the ERK and AKT signaling pathways
Authors: Salas-Ramirez, K.Y., Bagnall C., Frias L., Abdali S.A., Ahles T.A., Hubbard K. Chemotherapy on hippocampal extracellular signal-regulated kinase/Akt expression, locomotion/exploration, spatial learning and object recognition in ovariectomized and control female rats
Salas-Ramirez, K.Y., Bagnall C., Frias L., Abdali S.A., Ahles T.A., Hubbard K. - 2015
Behavioral and cognitive changes after early postnatal lesions of the rat mediodorsal thalamus
Authors: Ouhaz, Z., Ba-M'hamed S., Mitchell A.S., Elidrissi A., Bennis M. Mediodorsal thalamus early post-natal lesions on prefrontal neuron proliferation, locomotion/exploration, spatial learning, passive avoidance and social interaction in adult rats
Ouhaz, Z., Ba-M'hamed S., Mitchell A.S., Elidrissi A., Bennis M. - 2015
Sex and strain influence attribution of incentive salience to reward cues in mice
Authors: Dickson, P.E., McNaughton K.A., Hou L., Anderson L.C., Long K.H., Chesler E.J. Exploratory activity and rewarded Pavlovian/operant conditioning in male and female mice of different strains
Dickson, P.E., McNaughton K.A., Hou L., Anderson L.C., Long K.H., Chesler E.J. - 2015
Behavioral effects of deep brain stimulation of different areas of the Papez circuit on memory- and anxiety-related functions
Authors: Hescham, S., Jahanshahi A., Meriaux C., Lim L.W., Blokland A., Temel Y. Hippocampal, thalamic and entorhinal stimulation on exploratory activity, object location performance and hippocampal, prefrontal c-fos expression in scopolamine-treated rats
Hescham, S., Jahanshahi A., Meriaux C., Lim L.W., Blokland A., Temel Y. - 2015