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2016
Spinosin, a C-glycoside flavonoid, enhances cognitive performance and adult hippocampal neurogenesis in mice
Authors: Lee, Y., Jeon S.J., Lee H.E., Jung I.H., Jo Y.-W., Lee S., Cheong J.H., Jang D.S., Ryu J.H. C-glycoside flavonoid spinosin on passive avoidance and hippocampal neurogenesis and extracellular signal-regulated kinase, CREB and brain derived neurotrophic factor expression in mice
Lee, Y., Jeon S.J., Lee H.E., Jung I.H., Jo Y.-W., Lee S., Cheong J.H., Jang D.S., Ryu J.H. - 2016
Preventive effects of Salvia officinalis L. against learning and memory deficit induced by diabetes in rats: possible hypoglycaemic and antioxidant mechanisms
Authors: Hasanein, P., Felehgari Z., Emamjomeh A. Salvia officinalis L. idroalcoholic extract on streptozotocin inducing diabetes passive avoidance impairment and antioxidant effects in rats
Hasanein, P., Felehgari Z., Emamjomeh A. - 2016
Fingolimod (FTY720) improves hippocampal synaptic plasticity and memory deficit in rats following focal cerebral ischemia
Authors: Nazari, M., keshavarz S., Rafati A., Namavar M.R., Haghani M. Fingolimod neuroprotective, focal cerebral ischemia-induced passive avoidance and hippocampal neuron excitability impairment effects in rats
Nazari, M., keshavarz S., Rafati A., Namavar M.R., Haghani M. - 2016
Memory-enhancing effects of Cuscuta japonica Choisy via enhancement of adult hippocampal neurogenesis in mice
Authors: Moon, M., Jeong H.U., Choi J.G., Jeon S.G., Song E.J., Hong S.-P., Oh M.S. Cuscuta japonica Choisy extract and piracetam on passive avoidance, object recognition and hippocampal neurogenesis in mice
Moon, M., Jeong H.U., Choi J.G., Jeon S.G., Song E.J., Hong S.-P., Oh M.S. - 2016
Enriched endogenous n-3 polyunsaturated fatty acids alleviate cognitive and behavioral deficits in a mice model of Alzheimer's disease
Authors: Wu, K., Gao X., Shi B., Chen S., Zhou X., Li Z., Gan Y., Cui L., Kang J.X., Li W., Huang R. Omega-3 polyunsaturated fatty acids on locomotion, exploration and cortical and hippocampal neuronal degeneration in APPTg and control mice
Wu, K., Gao X., Shi B., Chen S., Zhou X., Li Z., Gan Y., Cui L., Kang J.X., Li W., Huang R. - 2016
Effects of peptides from Phascolosoma esculenta on spatial learning and memory via anti-oxidative character in mice
Authors: Liu, L., Cao J., Chen J., Zhang X., Wu Z., Xiang H. Phoscolasoma esculenta peptides on hippocampal CREB, brain-derived neurotrophic factor and NR2A-B expression, locomotor activity and Morris water maze performance in mice
Liu, L., Cao J., Chen J., Zhang X., Wu Z., Xiang H. - 2016
Xanthoceras sorbifolia extracts ameliorate dendritic spine deficiency and cognitive decline via upregulation of BDNF expression in a rat model of Alzheimer's disease
Authors: Li, Y., Xu J., Xu P., Song S., Liu P., Chi T., Ji X., Jin G., Qiu S., Hou Y., Zheng C., Wang L., Meng D., Zou L. Donepezil and Xanthoceras sorbifolia extracts on hippocampal plasticity, brain derived neurotrophic factor levels, spatial learning, passive avoidance and object recognition in intracerebroventricular amyloid β25-35 injected rats
Li, Y., Xu J., Xu P., Song S., Liu P., Chi T., Ji X., Jin G., Qiu S., Hou Y., Zheng C., Wang L., Meng D., Zou L. - 2016
Preclinic profile of ITI-214, an inhibitor of phosphodiesterase 1, for enhancement of memory performance in rats
Authors: Snyder, G.L., Prickaerts J., Wadenberg M.-L., Zhang L., Zheng H., Yao W., Akkerman S., Zhu H., Hendrick J.P., Vanover K.E., Davis R., Li P., Mates S., Wennogle L.P. Phosphodiesterase 1 inhibitor ITI-214 on object recognition and active avoidance performance in rats
Snyder, G.L., Prickaerts J., Wadenberg M.-L., Zhang L., Zheng H., Yao W., Akkerman S., Zhu H., Hendrick J.P., Vanover K.E., Davis R., Li P., Mates S., Wennogle L.P. - 2016
Icariside II, a novel phosphodiesterase-5 inhibitor, attenuates streptozotocin-induced cognitive deficits in rats
Authors: Yin, C., Deng Y., Gao J., Li X., Liu Y., Gong Q. Phosphodiesterase-5 inhibitor icariside II on hippocampal neuronal damage by intracerebroventricular sterptozotocin and related Morris water maze performance impairment in rats
Yin, C., Deng Y., Gao J., Li X., Liu Y., Gong Q. - 2016
Rosemary extract improves cognitive deficits in a rats model of repetitive mild traumatic brain injury associated with reduction of astrocytosis and neuronal degeneration in hippocampus
Authors: Song, H., Xu L., Zhang R., Cao Z., Zhang H., Yang L., Guo Z., Qu Y., Yu J. Rosemary extract on mild traumatic brain injury induced hippocampal neurodegeneration-inflammation and spatial learning impairment in rats
Song, H., Xu L., Zhang R., Cao Z., Zhang H., Yang L., Guo Z., Qu Y., Yu J. - 2016
Neuroprotective and memory enhancing effects of auraptene in a rat model of vascular dementia: experimental study and histopathological evaluation
Authors: Ghanbarabadi, M., Iranshahi M., Amoueian S., Mehri S., Motamedshariaty V.S., Mohajeri S.A. Citrus coumarin auraptene on brain ischemia-induced Morris water maze impairment and hippocampal lipid peroxidation, glutathione levels in rats
Ghanbarabadi, M., Iranshahi M., Amoueian S., Mehri S., Motamedshariaty V.S., Mohajeri S.A. - 2016
Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model
Authors: Xing, M., Sun Q., Wang Y., Cheng Y., Zhang N. Hydroxysafflor yellow A on Morris water maze performance, hippocampal long-term potentiation, brain-derived neurotrophic factor and NMDA expression and neurodegeneration in a vascular dementia rat model
Xing, M., Sun Q., Wang Y., Cheng Y., Zhang N. - 2016
Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus
Authors: Wang, P., Cao Y., Yu J., Liu R., Bai B., Qi H., Zhang Q., Guo W., Zhu H., Qu L. Flavonoid baicalin on ischemia-induced Morris water maze impairment and hippocampal calcium-calmodulin kinase II phosphorylation and neurodegeneration in gerbils
Wang, P., Cao Y., Yu J., Liu R., Bai B., Qi H., Zhang Q., Guo W., Zhu H., Qu L. - 2016
Icariside II, a novel phosphodiesterase-5 inhibitor, attenuates streptozotocin-induced coignitive deficits in rats
Authors: Yin, C., Deng Y., Gao J., Li X., Liu Y., Gong Q. Phosphodiesterase-5 inhibitor icariside II on streptozotocin-induced Morris water maze impairment, hippocampal neurodegeneration and phosphodiesterase type 5 protein, amyloid β1-42 levels in rats
Yin, C., Deng Y., Gao J., Li X., Liu Y., Gong Q. - 2016
Ginsenoside Rb1 as a neuroprotective agent: a review
Authors: Ahmed, T., Raza S.H., Maryam A., Setzer W.N., Braidy N., Nabavi S.F., de Oliveira M.R., Nabavi S.M. Ginsenoside Rb1 and neuroprotection - Review
Ahmed, T., Raza S.H., Maryam A., Setzer W.N., Braidy N., Nabavi S.F., de Oliveira M.R., Nabavi S.M. - 2016
Morin reverses neuroptahological and cognitive impairments in APPswe/PS1dE9 mice by trageting multiple pathogenic mechanisms
Authors: Du, Y., Qu J., Zhang W., Bao M., Zhou Q., Zhang Z., Li Z., Miao J. Bioflavonoid morin on hippocampal and cortical neurodegeneration, synaptic protein and amyloid β levels and spatial learning in APP and control mice
Du, Y., Qu J., Zhang W., Bao M., Zhou Q., Zhang Z., Li Z., Miao J. - 2016
Icariin, a major consitutent from Epimedium brevicornum, attenuates ibotenic acid-induced excitotoxicity in rat hippocampus
Authors: Zong, N., Li F., Deng Y., Shi J., Jin F., Gong Q. Flavonoid icariin on hippocampal neurotoxicity and Morris water maze performance impairment induced by intra-nucleus basalis magnocellularis ibotenic acid microinjection in rats
Zong, N., Li F., Deng Y., Shi J., Jin F., Gong Q. - 2016
Donepezil, an acetylcholine esterase inhibitor, and ABT-239, a histamine H3 receptor antagonist/inverse agonist, require the integrity of brain histamine system to exert biochemical and procognitive effects in the mouse
Authors: Provensi, G., Costa A., Passani M.B., Blandina P. Histaminergic system and glycogen synthase kinase 3β role in donepezil and H3 antagonists effects on object recognition in mice
Provensi, G., Costa A., Passani M.B., Blandina P. - 2016
The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats
Authors: Sadek, B., Khan N., Darras F.H., Pockers S., Decker M. Acetylcholinestearse inhibitor and H3 antagonists on passive avoidance impairment induced byscopolamine or NMDA antagonist dizocilpine in rats
Sadek, B., Khan N., Darras F.H., Pockers S., Decker M. - 2016
β-asarone improves learning and memory and reduces acetyl cholinesterase and beta-amyloid 42 levels in APP/PS1 transgenic mice by regulating beclin-1-dependent autophagy
Authors: Deng, M., Huang L., Ning B., Wang N., Zhang Q., Zhu C., Fang Y. β-asarone, aricept, 3-methyladenine, rapamycin and LY2940092 on hippocampal acetylcholinesterase, proteins, amyloid β42 levels, Morris water maze and passive avoidance performance in APP/PS1 mice
Deng, M., Huang L., Ning B., Wang N., Zhang Q., Zhu C., Fang Y. - 2016
Cognitive assessment of pycnogenol therapy following traumatic brain injury
Authors: Scheff, S.W., Roberts K.N. Pycnogenol on unilateral cortical brain injury spatial learning impairment in rats
Scheff, S.W., Roberts K.N. - 2016
Protective effects of chronic treatment with a standardized extract of Ginkgo biloba L. in the prefrontal cortex and dorsal hippocampus of middle-aged rats
Authors: Ribeiro, M.L., Moreira L.M:, Arcari D.., dos Sntos L.F., Marques A.C., Pedrazzoli J. Jr., Cerutti S.M. Ginkgo biloba extract on prefrontal and hippocampal neuroprotection and exploratory activity in middle-aged rats
Ribeiro, M.L., Moreira L.M:, Arcari D.., dos Sntos L.F., Marques A.C., Pedrazzoli J. Jr., Cerutti S.M. - 2016
Effect of botanical extracts containing carnosic acid or rosmarinic acid on learning and memory in SAMP8 mice
Authors: Farr, S.A., Niehoff M.L., Ceddia M.A., Herrlinger K.A., Lewis B.J., Feng S., Welleford A., Butterfield D.A., Morley J.E. Rosmarinic and carnosic acids on brain oxidative stress, blood triglyceride levels, active avoidance, appetitive operant conditioning and object location and recognition in SAMP8 mice
Farr, S.A., Niehoff M.L., Ceddia M.A., Herrlinger K.A., Lewis B.J., Feng S., Welleford A., Butterfield D.A., Morley J.E. - 2016
Spermidine suppresses age-associated memory impairment by preventing adverse increase of presynaptic active zone size and release
Authors: Gupta, V.K., Pech U., Bhukel A., Fulterer A., Ender A., Mauermann S.F., Andlauer T.F.M., Antwi-Adjei E., Beuschel C., Thriene K., Maglione M., Quentin C., Bushow R., Schwarzel M., Mielke T., Madeo F., Dengjel J., Fiala A., Sigrist S.J. Spermidine on aging-dependent olfactory avoidance memory impairment in Drosophila: synaptic plasticity study
Gupta, V.K., Pech U., Bhukel A., Fulterer A., Ender A., Mauermann S.F., Andlauer T.F.M., Antwi-Adjei E., Beuschel C., Thriene K., Maglione M., Quentin C., Bushow R., Schwarzel M., Mielke T., Madeo F., Dengjel J., Fiala A., Sigrist S.J. - 2016
Effects of the methanolic extract of Vitellaria paradoxa stem bark against scopolamine-induced cognitive dysfunction and oxidative stress in the rat hippocampus
Authors: Foyet, H.S., Asongalem A.E., Oben E.K., Cioanca O., Hancianu M., Hritcu L. Vitellaria paradoxa stem bark extract on scopolamine-induced hippocampal oxidative stress, object recognition and spatial learning impairment in rats v
Foyet, H.S., Asongalem A.E., Oben E.K., Cioanca O., Hancianu M., Hritcu L. - 2016
Alpha-tocopherol quinine ameliorates spatial memory deficits by reducing beta-amyloid oligomers, neuroinflammation and oxidative stress in transgenic mice with Alzheimer's disease
Authors: Wang, S., Yang S., Liu W, Zhang Y., Xu P., Wang T., Ling T., Liu R. α-tocopherol quinine on Morris water maze performance and brain oxidative stress in APP/PS1 amyloid β overexpressing mice
Wang, S., Yang S., Liu W, Zhang Y., Xu P., Wang T., Ling T., Liu R. - 2016
Rolipram-induced improvement of cognitive function correlates with changes in hippocampal CREB phosphorylation, BDNF and Arc protein levels
Authors: Zhong, Y., Zhu Y., He T., Li W., Yan H., Miao Y. Rolipram on Morris water maze performance and hippocampal CREB/brain-derived neurotrophic factor/Arc expression impairment by streptozotocin-induced diabetic and control rats
Zhong, Y., Zhu Y., He T., Li W., Yan H., Miao Y. - 2016
Betaine reverses the memory impairments in a chronic cerebral hypoperfusion rat model
Authors: Chunjie, N., Huijuan N., Zhao Y., Jianzhao W., Xiaojian Z. Betaine on hypoperfusion-induced spatial Learning impairment and hippocampal synaptic protein levels, oxidative stress status in rats
Chunjie, N., Huijuan N., Zhao Y., Jianzhao W., Xiaojian Z. - 2016
Phenylethanoid glycosides of Pedicularis muscicola Maxim ameliorate high altitude-induced memory impairment
Authors: Zhou, B., Li M., Cao X., Zhang Q., Liu Y., Ma Q., Qiu Y., Luan F., Wang X. Phenilethanoid glycosides on hypobaric hypoxia induced spatial memory and hippocampal oxidative stress deficits in rats
Zhou, B., Li M., Cao X., Zhang Q., Liu Y., Ma Q., Qiu Y., Luan F., Wang X. - 2016
PMC-12, atraditional herbal medicine, enhances learning memory and hippocampal neurogenesis in mice
Authors: Park, H.R., Kim J.Y., Lee Y., Chun H.J., Choi Y.W., Shin H.K., Choi B.T., Kim C.M., Lee J. Orally PMC-12 extract administration on spatial learning, hippocampal brain-derived neurotrophic factor/CREB levels and neurogenesisi/plasticity in mice
Park, H.R., Kim J.Y., Lee Y., Chun H.J., Choi Y.W., Shin H.K., Choi B.T., Kim C.M., Lee J. - 2016