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2015
Pharmacologcal depletion of serotonin in the basolateral amygdala complex reduces anxiety and disrupts fear conditioning
Authors: Johnson, P.L., Molosh A., Fitz S.D., Arendt D., Deehan G.A., Federici L.M., Bernabe C., Engleman E.A., Rodd Z.A., Lowry C.A., Shekhar A. Basolateral amygdala serotonin depletion by 5-7-DHT on fear conditioning, social interaction and exploratory activity in rats
Johnson, P.L., Molosh A., Fitz S.D., Arendt D., Deehan G.A., Federici L.M., Bernabe C., Engleman E.A., Rodd Z.A., Lowry C.A., Shekhar A. - 2015
Immediate post-defeat infusions of the noradrenergic receptor antagonist propranolol impair the consolidation of conditioned defeat in male Syrian hamsters
Authors: Gray, C.L., Krebs-Kraft D.L., Solomon M.B., Norvelle A., Parent M.B., Huhman K.L. Propranolol on locomotion/exploration/grooming and conditioned defeat consolidation in hamsters
Gray, C.L., Krebs-Kraft D.L., Solomon M.B., Norvelle A., Parent M.B., Huhman K.L. - 2015
Activation and blockade of serotonin7 receptors in the prelimbic cortex regulate depressive-like behaviors in a 6-hydroxydopamine-induced Parkinson's disease rat model
Authors: Zhang, Q.J., Du C.X., Tan H.H., Zhang L., Li L.B., Zhang J., Niu X.L., Liu J. Prefrontal 5-HT7 receptor modulation on locomotion/exploration, sucrose preference, response to stress and brain dopamine/serotonin/norepinephrine levels in unilateral substantia nigra/ventral tegmental area 6-OHDA-lesioned and control rats
Zhang, Q.J., Du C.X., Tan H.H., Zhang L., Li L.B., Zhang J., Niu X.L., Liu J. - 2015
Enhancing tyrosine hydroxylase and tryptophan hydorxylase expression and improving oxidative stress involved in the antidepressant effect of sodium valproate on rats undergoing chronic unpredicted stress
Authors: Qiu, H.-M., Yang J.-X., Jiang X.-H., Hu X.-Y., Liu D., Zhou Q.-X. Sodium valproate on stress effects on prefrontal tyrosine/tryptophan hydorxylase level, response to stress, exploratory activity and oxidative stress level in rats
Qiu, H.-M., Yang J.-X., Jiang X.-H., Hu X.-Y., Liu D., Zhou Q.-X. - 2015
Role of hippocampal β-adrenergic and glucocorticoid receptors in the novelty-induced enhancement of fear extinction
Authors: Liu, J.-F., Yang C., Deng J.-H., Yan W., Luo Y.-X., Shi H.-S., Meng S.-Q., Chai B.-S., Fang Q., Chai N., Xue Y.-X., Sun J., Chen C., Wang X.-Y., Wang J.-S., Lu L. Intra-hippocampal propranolol, glucocorticoid antagonist, protein kinase A and extracellular signal-regulated kinase 1/2 inhibitors pre novelty-induced open field exposition administration on consolidate fear conditioning extinction and subcessive reinstatement in rats
Liu, J.-F., Yang C., Deng J.-H., Yan W., Luo Y.-X., Shi H.-S., Meng S.-Q., Chai B.-S., Fang Q., Chai N., Xue Y.-X., Sun J., Chen C., Wang X.-Y., Wang J.-S., Lu L. - 2015
Negative energy balance blocks neural and behavioral responses to acute stress by "silencing" central glucagon-like peptide 1 signaling in rats
Authors: Maniscalco, J.W., Zheng H., Gordon P.J., Rinaman L. Fasting on exploratory activity, stratle reflex response, response to stress and brain c-fos expression in rats: noradrenergic prolactin-releasing peptide and glucagon-like peptide 1 neuron role
Maniscalco, J.W., Zheng H., Gordon P.J., Rinaman L. - 2015
Neurotransmitter-mediated anxiogenic action of PACAP-38 in rats
Authors: Telegdy, G., Adamik A. Neurotransmitter modulation of pituitary adenylate cyclase-activating polypeptide-38 effects onexploratory activity in rats
Telegdy, G., Adamik A. - 2015
Repeated stressor exposure enhances contextual fear memory in a beta-adrenergic receptor-dependent process and increases impulsivity in a non-beta receptor-dependent fashion
Authors: Camp, R.M., Johnson J.D. Stress and propranolol on exploratory activity, fear conditioning and passive avoidance in rats
Camp, R.M., Johnson J.D. - 2015
Early-life stress induces anxiety-like behaviors and activity imbalances in the medial prefrontal coertx and amygdala in adult rats
Authors: Ishikawa, J., Nishimura R., Ishikawa A. Early-life stress on exploratory grooming, rearing and freezing behaviors and related prefrontal and amygdalar c-fos expression in adult rats
Ishikawa, J., Nishimura R., Ishikawa A. - 2015
Neuronal circuits for fear and anxiety
Authors: Tovote, P., Fadok J.P., Luthi A. Fear and anxiety - Review
Tovote, P., Fadok J.P., Luthi A. - 2015
Dorsal periaqueductal gray post-stimulation freezing is counteracted by neurokinin-1 receptor antagonism in the central nucleus of the amygdala in rats
Authors: Carvalho, M.C., Santos J.M., Brandao M.L. Amygdalar substance P modulation of freezing induced by periaqueductal gray stimulation in rats
Carvalho, M.C., Santos J.M., Brandao M.L. - 2015
Selective information routing by ventral hippocampal CA1 projection neurons
Authors: Ciocchi, S., Passecker J., Malagon-Vina H., Mikus N., Klausberger T. Ventral hippocampal neuron firing during spatial learning and exploration in rats
Ciocchi, S., Passecker J., Malagon-Vina H., Mikus N., Klausberger T. - 2015
Chronic stress induces anxiety via an amygdalar intracellular cascade that impairs endocannabinoid signaling
Authors: Qin, Z., Zhou X., Pandey N.R., Vecchiarelli H.A., Stewart C.A., Zhang X., Lagace D.C., Brunel J.M., Beique J.-C., Stewart A.F.R., Hill M.N., Chen H.-H. Amygdalar CB1 receptor role in neuron excitability, passive avoidance, neophobia, exploratory activity and response to stress in male and female mice: mGluR5 and extracellular signal-regulated kinase modulation
Qin, Z., Zhou X., Pandey N.R., Vecchiarelli H.A., Stewart C.A., Zhang X., Lagace D.C., Brunel J.M., Beique J.-C., Stewart A.F.R., Hill M.N., Chen H.-H. - 2015
Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats
Authors: Glover, M.E., Pugh P.C., Jackson N.L., Cohen J.L., Fant A.D., Akil H., Clinton S.M. Prenatal/perinatal dam paroxetine exposureon maternal behavior and response to stress, locomotion/exploration in low- and high-responder rat offspring of different ages
Glover, M.E., Pugh P.C., Jackson N.L., Cohen J.L., Fant A.D., Akil H., Clinton S.M. - 2015
The effects of social defeat on behavior and dopaminergic markers in mice
Authors: Jin, H.-M., Shrestha Muna S., Bagalkot T.R., Cui Y., Yadav B.K., Chung Y.-C. Social stress on locomotion/exploration, response to stress, Morris water maze performance, social interaction and prefrontal, amygdalar and hippocampal dopamine receptor expression in mice
Jin, H.-M., Shrestha Muna S., Bagalkot T.R., Cui Y., Yadav B.K., Chung Y.-C. - 2015
Genetic mapping of ASIC4 and contrasting phenotype to ASIC1a in modulating innate fear and anxiety
Authors: Lin, S.-H., Chien Y.-C., Chiang W.-W., Liu Y.-Z., Lien C.-C., Chen C.-C. ASIC gene brain expression on spontaneous and conditioned behaviors of mice
Lin, S.-H., Chien Y.-C., Chiang W.-W., Liu Y.-Z., Lien C.-C., Chen C.-C. - 2015
Impairment in the aversive memory of mice in the inhibitory avoidance task but not in the elevated plus maze through intra-amygdala injections of histamine
Authors: Daher, F., Mattioli R. Intra-amygdala histamine injection on passive avoidance and exploratory activity in mice
Daher, F., Mattioli R. - 2015
Free and Easy Wanderer Plus (FEWP) improves behavioral deficits in an animal model of post-traumatic stress disorder by stimulating allopregnanolone biosynthesis
Authors: Qiu, Z.-K., Zhang G.-H., He J.-L., Ma J.-C., Zeng J., Shen D., Shen Y.-G., Chen J.-S., Liu C.-Y. "Free and easy wanderer plus" chinese medicine on locomotion/exploration and fear conditioning impairment induced by stress in male rats: brain allopregnenolone levels study
Qiu, Z.-K., Zhang G.-H., He J.-L., Ma J.-C., Zeng J., Shen D., Shen Y.-G., Chen J.-S., Liu C.-Y. - 2015
Forebrain NR2B overexpression enhancing fear acquisition and long-term potentiation in the lateral amygdala
Authors: Duan, Y., Zhou S., ma J., Yin P., Cao X. Forebrain NR2B receptor expression on thalamus-lateral amygdala projection excitability, exploraory activity, response to stress and fear conditioning in mice
Duan, Y., Zhou S., ma J., Yin P., Cao X. - 2015
Inactivation of BRD7 results in impaired cognitive behavior and reduced synaptic plasticity of the medial prefrontal cortex
Authors: Xu, Y., Cao W., Zhou M., Li C., Luo Y., Wang H., Zhao R., Jiang S., Yang J., Liu Y., Wang X., Li X., Xiong W., ma J., Peng S., Zeng Z., Li X., Tan M., Li G. Brain BRD7 protein expression on plasticity, response to stress, exploratory activity and cognitive behavior in mice
Xu, Y., Cao W., Zhou M., Li C., Luo Y., Wang H., Zhao R., Jiang S., Yang J., Liu Y., Wang X., Li X., Xiong W., ma J., Peng S., Zeng Z., Li X., Tan M., Li G. - 2015
Effects of phoenixin-14 on anxiolytic-like behavior in mice
Authors: Jiang, J.H., He Z., Peng Y.L:, Jin W.D., Mu J., Xue H.X., Wang Z., Chang M., Wang R. Phoenixin 14 neuropeptide intracerebroventricular or intra-hypothalamus or intra-amygdala on exploratory activity in mice: gonadotrophin, vasopressin/oxytocin modulation
Jiang, J.H., He Z., Peng Y.L:, Jin W.D., Mu J., Xue H.X., Wang Z., Chang M., Wang R. - 2015
NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDA-GluN2B antagonism
Authors: Kiselycznyk, C., Jury N.J., Halladay L.R., Nakazawa K., Mishina M., Sprengel R., Grant S.G.N., Svenningsson P., Holmes A. NMDAR, AMPAR and PSD-95 protein on exploratory activity and response to stress in mice: intra-prefrontal cortex and amygdala GluN2B antagonist effects
Kiselycznyk, C., Jury N.J., Halladay L.R., Nakazawa K., Mishina M., Sprengel R., Grant S.G.N., Svenningsson P., Holmes A. - 2015
Long-term effects of early adolescent stress: dysregulation of hypothalamic-pituitary-adrenal axis and central corticotropin releasing factor receptor 1 expression in adult male rats
Authors: Li, C., Liu Y., Yin S., Lu C., Liu D., Jiang H., Pan F. Stress on exploratory activity, spatial learning, corticotropin-releasing factor receptor 1 brain expression in rats: treadmill exercise and dexametazone administration effects
Li, C., Liu Y., Yin S., Lu C., Liu D., Jiang H., Pan F. - 2015
Strain and sex differences in brain and behaviour of adult rats: learning and memory, anxiety and volumetric estimates
Authors: Keeley, R.J., Bye C., Trow J., McDonald R.J. Brain volume, exploratory activity, fear conditioning and spatial learning in male and female rats of different strains
Keeley, R.J., Bye C., Trow J., McDonald R.J. - 2015
Part II: strain- and sex-specific effects of adolescent exposure to THC on adult brain and behaviour: variants of learning, anxiety and volumetric estimates
Authors: Keeley, R.J., Trow J., Bye C., McDonald R.J. Adolescent cannabinoid exposure on brain volume; spatial learning, fear conditioning and exploratory activity in adult male and female rats of different strain
Keeley, R.J., Trow J., Bye C., McDonald R.J. - 2015
5-HT1B autoreceptors differentially modulate the expression of conditioned fear in a circuit-specific manner
Authors: Liu, Y., Kelly M.A., Sexton T.J., Neumaier J.F. Amygdalar 5-HT1B role on fear conditioning and exploratory activity in mice
Liu, Y., Kelly M.A., Sexton T.J., Neumaier J.F. - 2015
Activating positive memory engrams suppresses depression-like behaviour
Authors: Ramirez, S., Liu X., MacDonald C.J., Moffa A., Zhou J., Redondo R.L., Tonegawa S. Glutamatergic hippocampus-amygdala-nucleus accumbens circuit on exploratory activity, response to stress, sucrose preference neophobia and hippocampal neurogenesis in mice
Ramirez, S., Liu X., MacDonald C.J., Moffa A., Zhou J., Redondo R.L., Tonegawa S. - 2015
Activation of 5-HT2a receptors in the basolateral amygdala promotes defeat-induced anxiety and the acquisition of conditioned defeat in Syrian hamsters
Authors: Clinard, C.T., Bader L.R., Sullivan M.A., Cooper M.A. Intra-basolateral amygdala 5-HT2A agonist or antagonist on social stress, exploratory activity and spatial learning in hamsters
Clinard, C.T., Bader L.R., Sullivan M.A., Cooper M.A. - 2015
Third trimester-equivalent ethanol exposure increases anxiety-like behavior and glutamatergic transmission in the basolateral amygdala
Authors: Baculis, B.C., Diaz M.R., Valenzuela C.F. Prenatal ethanol exposure on dams maternal care, exploratory activity and basolateral amygdala neuron excitability in adolescent rat offspring
Baculis, B.C., Diaz M.R., Valenzuela C.F. - 2015
Regulating anxiety with extrasynaptic inhibition
Authors: Botta, P., Demmou L., Kasugai Y., Markovic M., Xu C., Fadok J.P., Lu T., Poe M.M., Xu L., Cook J.M., Rudolph U., Sah P., Ferraguti F., Luthi A. Amygdala GABAergic modulation of protein kinase Cδ activity on exploratory activity and fear conditioning in mice
Botta, P., Demmou L., Kasugai Y., Markovic M., Xu C., Fadok J.P., Lu T., Poe M.M., Xu L., Cook J.M., Rudolph U., Sah P., Ferraguti F., Luthi A. - 2015