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2015
AVCRI104P3, a novel multitarget compound with cognition-enhancing and anxiolytic activities: studies in cognitively poor middle-aged mice
Authors: Gimenez-Llort, L., Ratia M., Perez B., Camps P., Munoz-Torrero D., Badia A., Clos M.V. Anticholinesterasic AVCRI104P3 and huprine X on exploratory activity and Morris water maze performance in middle-aged mice
Gimenez-Llort, L., Ratia M., Perez B., Camps P., Munoz-Torrero D., Badia A., Clos M.V. - 2015
LY293558 prevents soman-induced pathophysiological alterations in the basolateral amygdala and the development of anxiety
Authors: Prager, E.M., Figueiredo T.H., Long II R.P., Aroniadou-Anderjaska V., Apland J.P., Braga M.F.M. AMPA antagonist on soman-induced basolateral amygdala neuron excitability changes, exploratory acftivity and startle reflex response in rats
Prager, E.M., Figueiredo T.H., Long II R.P., Aroniadou-Anderjaska V., Apland J.P., Braga M.F.M. - 2015
Individual differences in the behavioral effects of nicotine: a review of the preclinical animal literature
Authors: Falco, A.M., Bevins R.A. Nicotine-induced behavior individual differences - Review
Falco, A.M., Bevins R.A. - 2015
Sodium selenite supplementation during pregnancy and lactation promotes anxiolysis and improves mnemnic performance in wistar rats'offspring
Authors: Laureano-Melo, R., do Imperio G.E., da Silva-Almeida C., Kluck G.E.G., de Azevedo Cruz Seara F., da Rocha F.F., Bezerra da Silveira A.L:, Reis L.C., Ortiga-Carvalho T.M., da Silva Cortes W. Sodium selenite during pregnancy and lactation on hippocampal acetylcholinesterase/TH expression, grooming, response to stress and object recognition in rat's offspring
Laureano-Melo, R., do Imperio G.E., da Silva-Almeida C., Kluck G.E.G., de Azevedo Cruz Seara F., da Rocha F.F., Bezerra da Silveira A.L:, Reis L.C., Ortiga-Carvalho T.M., da Silva Cortes W. - 2015
Modulatory effects of an NMDAR partial agonist in MK-801-induced memory impairment
Authors: Vishnoi, S., Raisudin S., Parvez S. D-cycloserine modulation of MK-801 effects on exploratory activity, conditioned taste aversion, object recognition and prefrontal acetylcholinesterase/monoamine oxidase/dopamine/c-fos expression in female rats
Vishnoi, S., Raisudin S., Parvez S. - 2015
Acute administration of nicotine into the higher order auditory Te2 cortex soecifically decreases the fear-related charge of remote emotional memories
Authors: Cambiaghi, M., Grosso A., Renna A., Concina G., Sacchetti B. Intra-temporal cortex nicotine on exploratory activity, auditory startle reflex, auditory fear conditioning acquisition, retrieval and reconsolidation in rats
Cambiaghi, M., Grosso A., Renna A., Concina G., Sacchetti B. - 2015
Evidence for the involvement of NMDA receptors in the antidepressant-like effect of nicotine in mouse forced swimming and tail suspension tests
Authors: Haj-Mirzaian, A., Kordjazy N., Haj-Mirzaian A., Ostadhadi S., Ghasemi M., Amiri S., Faizi M., Dehpour A.R. NMDA receptor modulation on nicotine effects on response to stress and locomotion/exploration in mice
Haj-Mirzaian, A., Kordjazy N., Haj-Mirzaian A., Ostadhadi S., Ghasemi M., Amiri S., Faizi M., Dehpour A.R. - 2015
Omega-3 polyunsaturated fatty acids in large doses attenuate seizures, cognitive impairment, and hippocampal oxidative DNA damage in young kindled rats
Authors: Abdel-Wahab, B.A., Al-Qahtani J.M., El-Safty S.A. Omega-3 fatty acids on pentylenetetrazole kindling-induced hippocampal oxidative stress, passive avoidance and exploratory activity impairment in rats
Abdel-Wahab, B.A., Al-Qahtani J.M., El-Safty S.A. - 2015
Omega 3 polyunsaturated fatty acids enhance the protective effect of levetiracetam against seizures, cognitive impairment and hippocampal oxidative DNA damage in young kindled rats
Authors: Abdel-Wahab, B.A., Shaikh I.A., Khateeb M.M., Habeeb S.M. Omega-3 and levetiracetam on hippocampal oxidative stress, exploratory and congitive impairment by kindling in rats
Abdel-Wahab, B.A., Shaikh I.A., Khateeb M.M., Habeeb S.M. - 2015
Chronic unpredictable mild stress induces parallel reductions of 15-PGDH in the hypothalamus and lungs in rats
Authors: Guo, J.-Y., Bian H., Yao Y. Stress on brain 15-PGDH and PGE2 prostaglandins, sucrose preference and exploratory activity in rats
Guo, J.-Y., Bian H., Yao Y. - 2015
Antidepressant-like effects of oleoylethanolamide in a mouse model of chronic unpredictable mild stress
Authors: Jin, P., Yu H.-L., Tian-Lan, Zhang F., Quan Z.-S. Oleoylethanolamide on stress-induced prefrontal/hippocampal vbrain-derived neurorophic factor, serum sdreno-cortico-tropic-hormone/corticosterone, exploratory activity, rearing and neophobia in mice
Jin, P., Yu H.-L., Tian-Lan, Zhang F., Quan Z.-S. - 2015
Blunted hypothalamo-pituitary adrenal axis response to predator odor predicts high stress reactivity
Authors: Whitaker, A.M., Gilpin N.W. Predator odor stress and hypothalamo-pituitary-adrenal axis response on exploratory activity in rats
Whitaker, A.M., Gilpin N.W. - 2015
Comparative effects of intranasal neuropeptide Y and HS014 in preventing anxiety and depressive-like behavior elicited by single prolonged stress
Authors: Sabban, E.L., Serova L.I., Alaluf L.G., Laukova M., Peddu C. Neuropeptide Y or melanocortin receptor 4 antagonist on response to stress, exploratory activity and ACTH/corticosterone plasma levels in rats
Sabban, E.L., Serova L.I., Alaluf L.G., Laukova M., Peddu C. - 2015
Disruption of peri-adolescent endocannabinoid signaling modulates adult neuroendocrine and behavioral responses to stress in male rats
Authors: Lee, T.T.-Y., Hill M.N., Hillard C.J., Gorzalka B.B. Peri-adolescent CB1 antagonist exposure on exploratory activity, response to stress, corticosterone/ACTH plasma levela and brain endocannabinoid receptor expression in adult rats
Lee, T.T.-Y., Hill M.N., Hillard C.J., Gorzalka B.B. - 2015
Acute isoproterenol induces anxiety-like behavior in rats and increases plasma content of extracellular vesicles
Authors: Leo, G., Guescini M., Genedani S., Stocchi V., Carone C., Filaferro M., Sisti D., Marcoli M., Maura G., Cortelli P., Guidolin D., Fuxe K., Agnati L.F. Isoproterenol on locomotion/exploration in rats
Leo, G., Guescini M., Genedani S., Stocchi V., Carone C., Filaferro M., Sisti D., Marcoli M., Maura G., Cortelli P., Guidolin D., Fuxe K., Agnati L.F. - 2015
Estradiol replacement enhances fear memory formation, impairs extinction and reduces COMT expression levels in the hippocampus of ovariectomized female mice
Authors: McDermott, C.M., Liu D., Ade C., Schrader L.A. 17β-estradiol on exploratory activity, hippocampal catechol-O-methyltransferase, pain sensitivity, fear conditioning acquisition and extinction in female mice
McDermott, C.M., Liu D., Ade C., Schrader L.A. - 2015
Statins enhance cognitive performance in object location test in albino Swiss mice: involvement of beta-adrenoceptors
Authors: Vandresen-Filho, S., Franca L.M., Alcantara-Junior J., Nogueira L.C., Marques de Brito T., Lopes L., Mesquita Junior F., Vanzeler M.L., Bertoldo D.B., Dias P.G., Colla A.R.S., Hoeller A., Duzzioni M., Rodrigues A.L.S., de Lima T.C.M., Tasca C.I., Viola G.G. Statins and β-adrenergic antagonist propranolol on exploratory activity and object location test in mice
Vandresen-Filho, S., Franca L.M., Alcantara-Junior J., Nogueira L.C., Marques de Brito T., Lopes L., Mesquita Junior F., Vanzeler M.L., Bertoldo D.B., Dias P.G., Colla A.R.S., Hoeller A., Duzzioni M., Rodrigues A.L.S., de Lima T.C.M., Tasca C.I., Viola G.G. - 2015
High aggression in rats is associated with elevated stress, anxiety-like behavior, and altered catecholamine content in the brain
Authors: Patki, G., Atrooz F., Alkadhi I., Solanki N., Salim S. Aggressive behavior on locomotion/exploration, hippocampal/amygdalar(prefrontal epinephrine/norepinephrine/dopamine levels and plasma corticosterone in rats of different strains
Patki, G., Atrooz F., Alkadhi I., Solanki N., Salim S. - 2015
Acute systemic LPS-mediated inflammation induces lasting changes in mouse cortical neuromodulation and behavior
Authors: Ming, Z., Sawicki G., Bekar L.K. Systemic lipopolysaccharide injection on cortical acetilcholine/serotonin/norepinephrine response, object recognition, exploratory activity and response to stress in mice
Ming, Z., Sawicki G., Bekar L.K. - 2015
The co-occurrence of zinc deficiency and social isolation has the opposite effects on mood compared with either condition alone due to changes in the central norepinephrine system
Authors: Mitsuya, H., Omata N., Kiyono Y., Mizuno T., Murata T., Mita K., Okazawa H., Wada Y. Social stress and zinc deficiency on exploratory activity, response to stress and brain norepinephrine levels in rats
Mitsuya, H., Omata N., Kiyono Y., Mizuno T., Murata T., Mita K., Okazawa H., Wada Y. - 2015
CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice
Authors: Onaka, Y., Shintani N., Nakazawa T., Haba R., Ago Y., Wang H., Kanoh T., Hayata-Takano A., Hirai H., Nagata K.Y., Nakamura M., Hashimoto R., Matsuda T., Waschek J.A., Kasai A., Nagayasu K., Baba A., Hashimoto H. Prostaglandin CRTH2 receptor role on locomotion/exploration, response to stress, neophobia, social interaction and brain norepinephrine in mice: corticosterone and pituitary adenylate cyclase-activating polypeptide modulation
Onaka, Y., Shintani N., Nakazawa T., Haba R., Ago Y., Wang H., Kanoh T., Hayata-Takano A., Hirai R., Nagata K., Nakamura M., Hashimoto R., Matsuda T., Waschek J.A., Kasai A., Nagayasu K., Baba A., Hashimoto H. - 2015
Neurochemical and electrophysiological deficits in the ventral hippocampus and selective behavioral alterations caused by high-fat diet in female C57BL/6 mice
Authors: Krishna, S., Keralapurath M.M., Lin Z., Wagner J.J., De La Serre C.B., Harn D.A., Filipov N.M. High-fat diet on brain monoamine levels, hippocampal excitability, exploratory activity and response to stress in mice
Krishna, S., Keralapurath M.M., Lin Z., Wagner J.J., De La Serre C.B., Harn D.A., Filipov N.M. - 2015
CRH engagement of the locus coeruleus noradrenergic system mediates stress-induced anxiety
Authors: McCall, J.G., Al-Hasani R., Siuda E.R., Hong D.Y., Norris A.J., Ford C.P., Bruchas M.R. Stress-induced noradrenergic locus coeruleus neuron firing and exploratori activity in mice: corticotropin-releasing hormone modulation
McCall, J.G., Al-Hasani R., Siuda E.R., Hong D.Y., Norris A.J., Ford C.P., Bruchas M.R. - 2015
Early prenatal exposure to LPS results in anxiety- and depression-related behaviors in adulthood
Authors: Depino, A.M. Prenatal lipopolysaccharide exposition on hippocampal norepinephrine/serotonin/reelin glycoprotein expression/neurogenesis, response to stress and exploratory activity in mouse offspring
Depino, A.M. - 2015
Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters
Authors: Aboul-Fotouh, S. Nicotinic antagonist mecamylamine on response to stress, sucrose preference social interaction, exploratory activity and prefrontal BDNF/serotonin/norepinephrine levels in rats
Aboul-Fotouh, S. - 2015
Hippocampal long-term potentiation that is eloicited by perforant path stimulation of that occurs in conjuction with spatial learning is tightly controlled by beta-adrenoceptors and the locus coeruleus
Authors: Hansen, N., Manahan-Vaughan D. Locus coeruleus stimulation on hippocampal long-term potentiation evolked by novel spatial exploration in rats
Hansen, N., Manahan-Vaughan D. - 2015
Activation of serotonin2C receptors in the lateral habenular nucleus increases the expression of depression-related behaviors in the hemiparkinsonian rat
Authors: Han, L.-N., Zhang L., Li L.-B., Sun Y.-N., Wang Y., Chen L., Guo Y., Zhang Y.-M., Zhang Q.-J., Liu J. Intra-lateral habenula 5-HT2C agonist or antagoinist on local glutamate neuron firing, brain monoamine levels, sucrose preference, exploratory activity and response to stress in unilateral substantia nigra 6-OHDA-lesioned and control rats
Han, L.-N., Zhang L., Li L.-B., Sun Y.-N., Wang Y., Chen L., Guo Y., Zhang Y.-M., Zhang Q.-J., Liu J. - 2015
Activation of 5-HT1A receptors in the medial subdivision of the central nucleus of the amygdala produces anxiolytic effects in a rat model of Parkinson's disease
Authors: Sun, Y.-N., Wang T., Wang Y., Han L.-N., Li L.-B., Zhang Y.-M., Liu J. Amygdala 5-HT1A modulation of locomotion/exploration, amygdalar GABAergic neuron firing and brain monoamine levels in 6-OHDA unilateral medial forebrain bundle lesioned and control rats
Sun, Y.-N., Wang T., Wang Y., Han L.-N., Li L.-B., Zhang Y.-M., Liu J. - 2015
Serotonin6 receptors in the dorsal hippocampus regulate depressive-like behaviors in unilateral 6-hydroxydopamine-lesioned Parkinson's rats
Authors: Liu, K.-C., Li J.-Y., Tan H.-H., Du C.-X., Xie W., Zhang Y.-M., Ma W.-L., Zhang L. Hippocampal 5-HT6 receptor modulation of brain monoamine levels, exploratory activity, sucrose preference and response to stress in unilateral 6-OHDA medial forebrain bundle lesioned and control rats
Liu, K.-C., Li J.-Y., Tan H.-H., Du C.-X., Xie W., Zhang Y.-M., Ma W.-L., Zhang L. - 2015
Serotonergic interaction between medial prefrontal cortex and mesotelencephalic system underlies cognitive and affective deficits in hemiparkinsonian rats
Authors: Petri, D., De Souza Silva M.A., Chao O.Y.-H., Schnitzler A., Huston J.P. Serotonergic modulation of prefrontal/medial forebrain bundle disconnection in rats: object recognition, locomotion/exploration, response to stress and prefrontal/striatal monoamine level study
Petri, D., De Souza Silva M.A., Chao O.Y.-H., Schnitzler A., Huston J.P. - 2015