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2016
BE360, a new selective estrogen receptor modulator, produces antidepressant and antidementia effects through the enhancement of hippocampal cell proliferation in olfactory bulbectomized mice
Authors: Nakagawasai, O., Nemoto W., Onogi H., Moriya T., Lin J.-R., Odaira T., Yaoita F., Ogawa T., Ohta K., Endo Y., Tan-No K. Estrogen receptor ligands on spatial learning, sucrose preference, hippocampal neurogenesis and CREB, brain derived neurotrophic factor expression in olfactory bulbectomized and control mice
Nakagawasai, O., Nemoto W., Onogi H., Moriya T., Lin J.-R., Odaira T., Yaoita F., Ogawa T., Ohta K., Endo Y., Tan-No K. - 2016
Object and spatial memory after neonatal perirhinal lesions in monkeys
Authors: Weiss, A.R., Bachevalier J., Neonatal or adult perirhinal lesions on recognition and spatial memory in monkeys
Weiss, A.R., Bachevalier J., - 2016
Chronic cerebral hypoperfusion induces long-lasting cognitive deficits accompanied by long-term hippocampal silent synapses increase in rats
Authors: Wang, Z., Fan J., Wang J., Li Y., Duan D., Du G., Wang Q. Cerebral hyperfusion on spatial learning, hippocampal AMPA, NMDA receptor expression, neuron number and dendritic spine density in rats
Wang, Z., Fan J., Wang J., Li Y., Duan D., Du G., Wang Q. - 2016
Effects of age, experience and inter-alpha inhibitor proteins on working memory and neuronal plasticity after neonatal hypoxia-ischemia
Authors: Gaudet, C.M., Lim Y.-P., Stonestreet B.S., Threlkeld S.W. Neonatal hypoxia-ischemia and inter-α inhibitor proteins exposure on hippocampal neuron plasticity, damage and Morris water maze performance in rats of different age
Gaudet, C.M., Lim Y.-P., Stonestreet B.S., Threlkeld S.W. - 2016
Delayed administration IL-1β neutralizing antibody improves cognitive function after transient global ischemia in rats
Authors: Zhao, B., Zou C., Zhou P. After transient ischemia interleukin-1β antobody administration on hippocampal neuron survival and Morris water maze performance in rats
Zhao, B., Zou C., Zhou P. - 2016
Dentate gyrus supports slope recognition memory, shades of grey-context pattern separation and recognition memory, and CA3 supports pattern completion for object memory
Authors: Kesner, R.P., Kirk R.A., Yu Z., Polansky C., Musso N.D. Hippocampal lesions on enviromental recognition memory in the rat
Kesner, R.P., Kirk R.A., Yu Z., Polansky C., Musso N.D. - 2016
Learning impairment by minimal cortical injury in a mouse model of Alzheimer's disease
Authors: Zou, J., Wang M., Uchiumi O., Shui Y., Ishigaki Y., Liu X., Tajima N., Akai T., Iizuka H., Kato N. Parietal cortex lesions by local glutamate injection on neuron excitability and Morris water maze performance in 3xTg Alzheimer's model and control mice
Zou, J., Wang M., Uchiumi O., Shui Y., Ishigaki Y., Liu X., Tajima N., Akai T., Iizuka H., Kato N. - 2016
Effect of delta opioid recetpro activation on spatial cognition and neurogenesis in cerebral ischemic rats
Authors: Wang, S.-Y., Duan Y.-L., Zhao B., Wang X.-R., Zhao Z., Zhang G.-M. Delta opioid modulation on spatial learning and hippocampal neurogenesis and apoptosis in cerebral ischemic and control rats
Wang, S.-Y., Duan Y.-L., Zhao B., Wang X.-R., Zhao Z., Zhang G.-M. - 2016
Pedunculopontine tegmental nucleus lesions impair probabilistic reversal learning by reducing sensitivity to positive reward feedback
Authors: Syed, A., Baker P.M., Ragozzino M.E. Pedunculopontine tegmental nucleus lesions and spatial discrimination learning in rats
Syed, A., Baker P.M., Ragozzino M.E. - 2016
Perirhinal cortex supports tactual discrimination tasks with increasing levels of complexity: retrograde effect
Authors: Ramos, J.M.J. Hippocampal and perirhinal lesions onm appetitive spatial learning in rats: tactual information study
Ramos, J.M.J. - 2016
Real-space path integration is imapired in Alzheimer's disease and mild cognitive impairment
Authors: Mokrisova, I., Laczo J., Andel R., Gazova I., Vyhnalek M., Nedelska Z., Levcik D., Cerman J., Vlcek K., Hort J. Hippocampal volume and entorhinal and inferior parietal cortex thickness on path integration impairment in humans
Mokrisova, I., Laczo J., Andel R., Gazova I., Vyhnalek M., Nedelska Z., Levcik D., Cerman J., Vlcek K., Hort J. - 2016
Icariside II, a novel phosphodiesterase-5 inhibitor, attenuates streptozotocin-induced cognitive deficits in rats
Authors: Yin, C., Deng Y., Gao J., Li X., Liu Y., Gong Q. Phosphodiesterase-5 inhibitor icariside II on hippocampal neuronal damage by intracerebroventricular sterptozotocin and related Morris water maze performance impairment in rats
Yin, C., Deng Y., Gao J., Li X., Liu Y., Gong Q. - 2016
Rosemary extract improves cognitive deficits in a rats model of repetitive mild traumatic brain injury associated with reduction of astrocytosis and neuronal degeneration in hippocampus
Authors: Song, H., Xu L., Zhang R., Cao Z., Zhang H., Yang L., Guo Z., Qu Y., Yu J. Rosemary extract on mild traumatic brain injury induced hippocampal neurodegeneration-inflammation and spatial learning impairment in rats
Song, H., Xu L., Zhang R., Cao Z., Zhang H., Yang L., Guo Z., Qu Y., Yu J. - 2016
Neuroprotective and memory enhancing effects of auraptene in a rat model of vascular dementia: experimental study and histopathological evaluation
Authors: Ghanbarabadi, M., Iranshahi M., Amoueian S., Mehri S., Motamedshariaty V.S., Mohajeri S.A. Citrus coumarin auraptene on brain ischemia-induced Morris water maze impairment and hippocampal lipid peroxidation, glutathione levels in rats
Ghanbarabadi, M., Iranshahi M., Amoueian S., Mehri S., Motamedshariaty V.S., Mohajeri S.A. - 2016
Early immature neuronal death is partially involved in memory impairment induced by cerebral ischemia
Authors: Yi, J.H., Cho S.Y., Jeon S.J., Jung J.W., Park M.S., Kim D.H., Ryu J.H. Cerebral ischemia on Morris water maze and hippocampal long-term potentiation, neurogenesis and neuron survival impairment in mice
Yi, J.H., Cho S.Y., Jeon S.J., Jung J.W., Park M.S., Kim D.H., Ryu J.H. - 2016
Hydroxysafflor yellow A increases BDNF and NMDARs in the hippocampus in a vascular dementia rat model
Authors: Xing, M., Sun Q., Wang Y., Cheng Y., Zhang N. Hydroxysafflor yellow A on Morris water maze performance, hippocampal long-term potentiation, brain-derived neurotrophic factor and NMDA expression and neurodegeneration in a vascular dementia rat model
Xing, M., Sun Q., Wang Y., Cheng Y., Zhang N. - 2016
Long-term electromagnetic pulse exposure induces Abeta deposition and cognitive dysfunction through oxidative stress and overexpression of APP and BACE1
Authors: Jiang, D.-P., Li J., Zhang J., Xu S.-L., Kuang F., Lang H.-Y., Wang Y.-F., An G.-Z., Li J., Guo G.-Z. Chronic electromagnetic field exposure on spatial learning and hippocampal neurodegeneration in rats
Jiang, D.-P., Li J., Zhang J., Xu S.-L., Kuang F., Lang H.-Y., Wang Y.-F., An G.-Z., Li J., Guo G.-Z. - 2016
Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus
Authors: Wang, P., Cao Y., Yu J., Liu R., Bai B., Qi H., Zhang Q., Guo W., Zhu H., Qu L. Flavonoid baicalin on ischemia-induced Morris water maze impairment and hippocampal calcium-calmodulin kinase II phosphorylation and neurodegeneration in gerbils
Wang, P., Cao Y., Yu J., Liu R., Bai B., Qi H., Zhang Q., Guo W., Zhu H., Qu L. - 2016
Icariside II, a novel phosphodiesterase-5 inhibitor, attenuates streptozotocin-induced coignitive deficits in rats
Authors: Yin, C., Deng Y., Gao J., Li X., Liu Y., Gong Q. Phosphodiesterase-5 inhibitor icariside II on streptozotocin-induced Morris water maze impairment, hippocampal neurodegeneration and phosphodiesterase type 5 protein, amyloid β1-42 levels in rats
Yin, C., Deng Y., Gao J., Li X., Liu Y., Gong Q. - 2016
MicroRNA-128-3p impaired water maze learning by suppressing doublecortin expression in both wild type and Aβ-42 infused mice
Authors: Chen, J., Li W., Li Y., He S., Li L., Liang L., Song Y., Qin D., Zheng H. MicroRNA-128-3p on spatial learning in control and amyloid β1-42 intracerebroventricular injected mice
Chen, J., Li W., Li Y., He S., Li L., Liang L., Song Y., Qin D., Zheng H. - 2016
Effects of metformin on inflammation and short-term memory in streptozotocin-induced diabetic mice
Authors: Oliveira, W.H., Nunes A.K., Franca M.E.R., Santos L.A., Los D.B., Rocha S.W., Barbosa K.P., Rodrigues G.B., Peixoto C.A. Metformin on streptozotocin-induced neuron degeneration, inflammation and spatial learning impairment in mice
Oliveira, W.H., Nunes A.K., Franca M.E.R., Santos L.A., Los D.B., Rocha S.W., Barbosa K.P., Rodrigues G.B., Peixoto C.A. - 2016
Comparable reduction in Zif268 levels and cytochrome oxidase activity in the retrosplenial cortex follo9wing mamillothalamic tract lesions
Authors: Frizzati, A., Milczarek M.M., Sengpiel F., Thomas K.L:, Dillingham C.M., Vann S.D. Mammillo-thalamic tract lesions on spatial learning and hippocampal and retroplenial cortex zif268 and cytochrome oxidase expression in rats
Frizzati, A., Milczarek M.M., Sengpiel F., Thomas K.L:, Dillingham C.M., Vann S.D. - 2016
Insulin potentiates the therapeutic effect of memantine against central STZ-induced spatial learning and memory deficit
Authors: Bahramian, A., Rastegar K., Namavar M.R., Moosavi M. Systemic memantin and/or intracerebroventricular insulin on intracerebroventricular streptozotocin-induced brain cell degeneration and Morris water maze impairment in rats
Bahramian, A., Rastegar K., Namavar M.R., Moosavi M. - 2016
Postischemia fish oil treatment restores long-term retrograde memory and dendritic density: an analysis of the time window of efficacy
Authors: Bacarin, C.C., Godinho J., de Oliveira R.M.W., Matsushita M., Gohara A.K., Cardozo-Filho L., de Carvalho Lima J., previdelli I.S., Melo S.R., Dal Molin Ribeiro M.H., Milani H. Fish oil on ischemic effects on hippocampal and cortical neuron death and plasticity and spatial memory in the rat
Bacarin, C.C., Godinho J., de Oliveira R.M.W., Matsushita M., Gohara A.K., Cardozo-Filho L., de Carvalho Lima J., previdelli I.S., Melo S.R., Dal Molin Ribeiro M.H., Milani H. - 2016
Global hypoxia induced impairment in learning and spatial memory is associated with precocious hippocampal aging
Authors: Biswal, S., Sharma D., Kumar K., Nag T.C., Barhwal K., Hota S.K., Kumar B. Global hypoxia on hippocampal neuron degenration and Morris water maze performance in young adult and aged rats
Biswal, S., Sharma D., Kumar K., Nag T.C., Barhwal K., Hota S.K., Kumar B. - 2016
Cannula implantation into the lateral ventricle does not adversely affect recognition or spatial working memory
Authors: Seyer, B., Pham V., Albiston A.L., Chai S.Y. Lateral ventricle cannulation and spatial and recognition working memory in rats - Technique
Seyer, B., Pham V., Albiston A.L., Chai S.Y. - 2016
Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer's disease
Authors: Shishido, H., Kishimoto Y., Kawai N., Toyota Y., Ueno M., Kubota T., Kirino Y., Tamiya T. Traumatic brain injury on hippocampal amyloid-β deposition and spatial learning deficit in Alzheimer's disease model mice
Shishido, H., Kishimoto Y., Kawai N., Toyota Y., Ueno M., Kubota T., Kirino Y., Tamiya T. - 2016
Morin reverses neuroptahological and cognitive impairments in APPswe/PS1dE9 mice by trageting multiple pathogenic mechanisms
Authors: Du, Y., Qu J., Zhang W., Bao M., Zhou Q., Zhang Z., Li Z., Miao J. Bioflavonoid morin on hippocampal and cortical neurodegeneration, synaptic protein and amyloid β levels and spatial learning in APP and control mice
Du, Y., Qu J., Zhang W., Bao M., Zhou Q., Zhang Z., Li Z., Miao J. - 2016
Icariin, a major consitutent from Epimedium brevicornum, attenuates ibotenic acid-induced excitotoxicity in rat hippocampus
Authors: Zong, N., Li F., Deng Y., Shi J., Jin F., Gong Q. Flavonoid icariin on hippocampal neurotoxicity and Morris water maze performance impairment induced by intra-nucleus basalis magnocellularis ibotenic acid microinjection in rats
Zong, N., Li F., Deng Y., Shi J., Jin F., Gong Q. - 2016
Peririhinal cortex lesions that impair object recognition memory spare landmark discriminations
Authors: Nelson, A.J.D., Olarte-Sanchez C.M., Amin E., Aggleton J.P. Perirhinal cortex lesions on object recognition and Morris water maze performance in rats
Nelson, A.J.D., Olarte-Sanchez C.M., Amin E., Aggleton J.P. - 2016