Themes: NOOTROPICS

2017

Contained in: Eur. J. Neurosci., 2017: 46, 1937-1953

Everyday memory: towards a translationally effective method of modelling the encoding, forgetting and enhancement of memory

Authors: Nonaka, M., Fitzpatrick R., Lapira J., Wheeler D., Spooner P.A., Corcoles-Parada M., Munoz-Lopez M., Tully T., Peters M., Morris R.G.M.

  Gene activation related to training and retraining in spatial/operant rewarded task in rats: rolipram exposure effects
  Nonaka, M., Fitzpatrick R., Lapira J., Wheeler D., Spooner P.A., Corcoles-Parada M., Munoz-Lopez M., Tully T., Peters M., Morris R.G.M. - 2017

  SPATIAL ORIENTATION AND SPATIAL MEMORY   OPERANT CONDITIONING   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   CONTEXTUAL PRE-EXPOSURE AND RETRAINING   RECALL AND RECONSOLIDATION   PROTEINS AND GENES
Contained in: Neuropharmacology, 2017: 126, 168-178

Maslinic acid ameliorates NMDA receptor blockade-induced schizophrenia-like behaviors in mice

Authors: Jeon, S.J., Kim E., Lee J.S., Oh H.K., Zhang J., Kwon Y., Jang D.S., Ryu J.H.

  Maslinic acid exposure on cataleptic behavior, MK-801-induced effects on prefrontal extracellular signal-regulated kinase and CREB levels, acoustic startle reflex and related prepulse inhibition, locomotor activity, social interaction and object recognition in mice
  Jeon, S.J., Kim E., Lee J.S., Oh H.K., Zhang J., Kwon Y., Jang D.S., Ryu J.H. - 2017

  STARTLE REFLEX   LOCOMOTOR ACTIVITY   ENVIRONMENT AND SOCIAL BEHAVIOR   NOOTROPICS   CEREBRAL CORTEX   PROTEINS AND GENES   PROTEIN KINASES   CONDITIONED AND UNCONDITIONED INHIBITION

2016

Contained in: Behav. Brain Res., 2016: 297, 155-164

The dual-acting H3 receptor antagonist and AChE inhibitor UW-MD-71 dose-dependently enhances memory retrieval and reverses dizocilpine-induced memory impairment in rats

Authors: Khan, N., Saad A., Nurulain S.M., Darras F.H., Decker M., Sadek B.

  Acetylcholinesterase inhibitors on locomotor activity, passive avoidance acquisition, consolidation and retrieval in rats: histaminergic modulation effects
  Khan, N., Saad A., Nurulain S.M., Darras F.H., Decker M., Sadek B. - 2016

  ACETYLCHOLINE   LOCOMOTOR ACTIVITY   AVOIDANCE   DARK/LIGHT CONTEXT   HISTAMINE   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS   RECALL AND RECONSOLIDATION   CONSOLIDATION
Contained in: Physiol. Behav., 2016: 154, 114-125

Protective effect of tetrahydropalmatine against D-galactose induced memory impairment in rat

Authors: Qu, Z., Zhang J., Yang H., Huo L., Gao J., Chen H., Gao W.

  Tetrahydropalmatine on D-galactose induced brain stress/acetylcholine levels, Morris water maze performance and locomotion/exploration impairment in rats
  Qu, Z., Zhang J., Yang H., Huo L., Gao J., Chen H., Gao W. - 2016

  ACETYLCHOLINE   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NITRIC AND NITROUS OXIDE   NOOTROPICS
Contained in: Psychopharmacology, 2016: 233, 599-613

A novel acetylcholinesterase inhibitor and calcium channel blocker SCR-1693 improves Aβ25-35-impaired mouse cognitive function

Authors: Zhang, Z., Chen R., An W., Wang C., Liao G., Dong X., Bi A., Yin Z., Luo L.

  Acetylcholinesterase inhibitor and calcium channel blocker on amyloid-β25-35-induced hippocampal neuron loss/excitability/CREB-Calcium calmodulin kinase II levels and spatial learning impairment in mice
  Zhang, Z., Chen R., An W., Wang C., Liao G., Dong X., Bi A., Yin Z., Luo L. - 2016

  ACETYLCHOLINE   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   PROTEIN KINASES   PROTEINS AND GENES
Contained in: Psychopharmacology, 2016: 233, 761-771

Effects of the nicotinic agonist varenicline on the performance of tasks of cognition in aged and middle-aged rhesus and pigtail monkeys

Authors: Terry, A.V. Jr., Plagenhoef M., Callahan P.M.

  Nicotinic agonist varenicline on spatial learning in aged and middle-aged monkeys
  Terry, A.V. Jr., Plagenhoef M., Callahan P.M. - 2016

  ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   AGE   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS
Contained in: Behav. Brain Res., 2016: 302, 73-80

Nicotinic α7 and α4β2 agonists enhance the formation and retrieval of recognition memory: potential mechanisms for cognitive performance enhancement in neurological and psychiatric disorders

Authors: McLean, S.L., Grayson B., Marsh S., Zarroug S.H.O., Harte M.K., Neill J.C.

  Donepezil, risperidone, nicotinic α7 and α4β2 agonists on object recognition acquisition and retrieval in rats
  McLean, S.L., Grayson B., Marsh S., Zarroug S.H.O., Harte M.K., Neill J.C. - 2016

  ACETYLCHOLINE   NOOTROPICS   RECALL AND RECONSOLIDATION
Contained in: Behav. Brain Res., 2016: 302, 142-151

The positive allosteric modulator of α7 nicotinic acetylcholine receptors, 3-furan-2-yl-N-p-tolyl-acrylamide, enhances memory processes and stimulates ERK1/2 phosphorylation in mice

Authors: Targowska-Duda, K.M., Wnorowski A., Budzynska B., Jozwiak K., Biala G., Arias H.R.

  α7 nicotinic acetylcholine agonists on locomotor activity, prefrontal/hippocampal extracellular signal-regulated kinase 1/2 expression, passive avoidance acquisition and consolidation in mice
  Targowska-Duda, K.M., Wnorowski A., Budzynska B., Jozwiak K., Biala G., Arias H.R. - 2016

  ACETYLCHOLINE   LOCOMOTOR ACTIVITY   AVOIDANCE   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   PROTEIN KINASES   CONSOLIDATION
Contained in: Neurosci. Lett., 2016: 612, 261-268

Effects of novel tacrine-related cholinesterase inhibitors in the reversal of 3-quinuclidinyl benzilate-induced cognitive deficit in rats - Is there a potential for Alzheimer's disease treatment?

Authors: Misik, J., Korabecny J., Nepovimova E., Kracmarova A., Kassa J.

  Cholinesterase inhibitors on 3-quinuclidinyl benzilate-induced cognitive deficit in rats
  Misik, J., Korabecny J., Nepovimova E., Kracmarova A., Kassa J. - 2016

  ACETYLCHOLINE   AVOIDANCE   SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS
Contained in: Neurobiol. Learn. Mem., 2016: 127, 34-41

The action of neuropeptide AF on passive avoidance learning. Involvement of neurotransmitters

Authors: Palotai, M., Telegdy G., Bagosi Z., Jaszberenyi M.

  Neuropeptide AF on passive avoidance consolidation in mice
  Palotai, M., Telegdy G., Bagosi Z., Jaszberenyi M. - 2016

  EPINEPHRINE AND NOREPINEPHRINE   ACETYLCHOLINE   DOPAMINE   OPIOIDS   NEUROPEPTIDES   NITRIC AND NITROUS OXIDE   NOOTROPICS   SEROTONIN   CONSOLIDATION
Contained in: Psychopharmacology, 2016: 233, 1235-1243

Antidepressant, anxiolytic and procognitive effects of rivastigmine and donepezil in the chronic mild stress model in rats

Authors: Papp, M., Gruca P., Lason-Tyburkiewicz M., Willner P.

  Rivastigmine and donepezil on chronic mild stress effects on locomotion/exploration, sucrose preference and object recognition in rats
  Papp, M., Gruca P., Lason-Tyburkiewicz M., Willner P. - 2016

  ACETYLCHOLINE   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   NOOTROPICS   STRESS
Contained in: Neurobiol. Learn. Mem., 2016: 130, 149-158

Concurrent assessment of memory for object and place: evidence for different preferential importance of perirhinal cortex and hippocampus and for promnestic effect of a neurokinin-3 R agonist

Authors: Chao, O.Y., Huston J.P., Nikolaus S., de Sozua Silva M.A.

  Neurokinin-3 R agonist on object location/recognition in perirhinal or hippocampal lesioned rats
  Chao, O.Y., Huston J.P., Nikolaus S., de Sozua Silva M.A. - 2016

  ACETYLCHOLINE   CENTRAL NERVOUS SYSTEM LESIONS   PERIRHINAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Behav. Brain Res., 2016: 303, 26-33

The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses

Authors: Vanmierlo, T., Creemers P., Akkerman S., van Duinen M., Sambeth A., De Vry J., Uz T., Blokland A., Prickaerts J.

  Phosphodiesterase type 4 inhibitors on spatial learning and recovery from ketamine/xylazine-induced anesthesia in mice
  Vanmierlo, T., Creemers P., Akkerman S., van Duinen M., Sambeth A., De Vry J., Uz T., Blokland A., Prickaerts J. - 2016

  ANESTHESIA   SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS   PROTEINS AND GENES
Contained in: Neuropharmacology, 2016:105, 72-83

D5 receptor agonist 027075 promotes cognitive function recovery and neurogenesis in a Aβ1-42-induced mouse model

Authors: Shen, L., Yan M., He L.

  D5 agonist, antagonist and donepezil on cortical neuron cAMP-acetylcholine content, platicity, neurogenesis, locomotion, exploration, Morris water maze, active and passive avoidance in intracerebroventricular Aβ1-42 injected and control mice
  Shen, L., Yan M., He L. - 2016

  ACETYLCHOLINE   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   AVOIDANCE   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   DOPAMINE   NOOTROPICS   NEUROGENESIS AND PLASTICITY
Contained in: Neuropharmacology, 2016: 105, 106-113

Subtype-selective nicotine acetylcholine receptor agonists can improve cognitive flexibility in an attentional set shifting task

Authors: Wood, C., Kohli S., Malcolm E., Allison C., Shoaib M.

  Acetylcholine nicotinic agonist and ketamine on appetitive operant discrimination task in rats
  Wood, C., Kohli S., Malcolm E., Allison C., Shoaib M. - 2016

  ACETYLCHOLINE   OPERANT CONDITIONING   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS
Contained in: Behav. Brain Res., 2016: 297, 91-103

Rosmarinic acid prevents against memory deficits in ischemic mice

Authors: Fonteles, A.A., de Souza C.M., de Sousa Neves J.C., Menezes A.P.F. Santos do Carmo M.R., Fernandes F.D.P., de Araujo P.R., de Andrade G.M.

  Rosmarinic acid cerebral ischemia effects on locomotion/exploration, spatial learning, neuroprotection and striatal/hippocampal brain derived neurotrophic factor/synaptophysin levels in mice
  Fonteles, A.A., de Souza C.M., de Sousa Neves J.C., Menezes A.P.F. Santos do Carmo M.R., Fernandes F.D.P., de Araujo P.R., de Andrade G.M. - 2016

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NOOTROPICS   STRIATUM
Contained in: Brain Res. Bull., 2016: 120, 144-150

Tempol prevents chronic leep-deprivation induced memory impairment

Authors: Alzoubi, K.H., Khabour O.F., Albawaana A.S., Alhashimi F.H., Athamneh R.Y.

  Tempol on sleep deprivation effects on exploratory activity, spatial learning and hippocampal oxidative stress in rats
  Alzoubi, K.H., Khabour O.F., Albawaana A.S., Alhashimi F.H., Athamneh R.Y. - 2016

  EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   SLEEP
Contained in: Behav. Brain Res., 2016: 305, 65-75

Protective effect of resveratrol against chronic intermittent hypoxia-induced spatial memory deficits, hippocampal oxidative DNA damage and increased p47Phox NADPH oxidase expression in young rats

Authors: Abdel-Wahab, B.A., Abdel-Wahab M.M.

  Resveratrol on hypoxia-induced exploratory activity, Morris water maze, oxidative stress impairment and DNA damage in young rats
  Abdel-Wahab, B.A., Abdel-Wahab M.M. - 2016

  EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   PROTEINS AND GENES
Contained in: Brain Res. Bull., 2016: 122, 62-70

Involvement of NMDA receptors and L-ariginine/nitric oxide/cyclic guanosine monophosphate pathway in the antidepressant-like effects of topiramate in mice forced swimming test

Authors: Ostadhadi, S., Khan M.I., Norouzi-Javidan A., Chamanara M., Jazaeri F., Zolfaghari S., Dehpour A.-R.

  NMDA, L-arginine, sildenafil, L-NAME and MK-801 on topiramate effects on response to stress and exploratory activity in mice
  Ostadhadi, S., Khan M.I., Norouzi-Javidan A., Chamanara M., Jazaeri F., Zolfaghari S., Dehpour A.-R. - 2016

  EXPLORATORY ACTIVITY   N-METHYL-D-ASPARTATE (NMDA)   NITRIC AND NITROUS OXIDE   NOOTROPICS   STRESS
Contained in: Behav. Brain Res., 2016: 306, 137-145

Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property

Authors: Lee, H.E., Jeon S.J., Ryu B., Park S.J., Ko S.Y., Lee Y., Kim E., Lee S., Kim H., Jang D.S., Ryu J.H.

  C-glucosylflavone swertisin on locomotion/exploration, scopolamine-induced passive avoidance/spatial learning impairment and cortical and hippocampal protein kinase A/CREB expression in mice: adenosine A1 receptor modulation
  Lee, H.E., Jeon S.J., Ryu B., Park S.J., Ko S.Y., Lee Y., Kim E., Lee S., Kim H., Jang D.S., Ryu J.H. - 2016

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   AVOIDANCE   ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   PROTEIN KINASES   PROTEINS AND GENES
Contained in: Neuroscience, 2016: 326, 69-83

Rolipram improves cognition, reduces anxiety- and despair-like behaviors and impacts hippocampal neuroplasticity after transient global cerebral ischemia

Authors: Soares, L.M., de Vry J., Steinbusch H.W.M., Milani H., Prickaerts J., De Oliveira R.M.W.

  Rolipram on transient cerebral ischemia effects on hippocampal plasticity and neurodegeneration, response to stress and exploratory activity in mice
  Soares, L.M., de Vry J., Steinbusch H.W.M., Milani H., Prickaerts J., De Oliveira R.M.W. - 2016

  EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   STRESS
Contained in: NeuroReport, 2016: 27, 652-658

Protective effects of myricetin on chronic stress-induced cognitive deficits

Authors: Wang, Q.-M., Wang G.-L., Ma Z.-G.

  Myricetin on stress effects on plasma adreno-cortico-tropic-hormone, Morris water maze performance and hippocampal brain derived neurotrophic factor in mice
  Wang, Q.-M., Wang G.-L., Ma Z.-G. - 2016

  ADRENO-CORTICO-TROPIC-HORMONE (ACTH)   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NOOTROPICS   STRESS
Contained in: Behav. Brain Res., 2016: 308, 24-37

Dimethyl fumarate attenuate intracerebroventricular streptozotocin-induced spatial memory impairment and hippocampal neurodegenration in rats

Authors: Majkutewicz, I., Kurowska E., Podlacha M., Myslinska D., Grembecka B., Rucinski J., Plucinska K., Jerzemowska G., Wrona D.

  Dimethylfumarate on intracerebroventricular streptozotocin-induced Morris water maze performance impairment and hippocampal and nucleus basalis magnocellularis neurodegeneration in rats
  Majkutewicz, I., Kurowska E., Podlacha M., Myslinska D., Grembecka B., Rucinski J., Plucinska K., Jerzemowska G., Wrona D. - 2016

  ACETYLCHOLINE   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   PROTEINS AND GENES
Contained in: Brain Res., 2016: 1644, 141-148

β-glucan attenuated scopolamine induced cognitive impairment via hippocampal acetylcholinesterase inhibition in rats

Authors: Haider, A., Inam W., Khan S.A., Hifza, Mahmood W., Abbas G.

  β-glucan and donepezil on hippocampal acetylcholinesterase activity, scopolamine-induced Morris water maze and locomotor impairment in rats
  Haider, A., Inam W., Khan S.A., Hifza, Mahmood W., Abbas G. - 2016

  ACETYLCHOLINE   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Brain Res., 2016: 1642, 219-225

Analysis of anti-depressant potential of curcumin against depression induced male albino wistar rats

Authors: Chang, X., Wang L., Li J., Wu D.

  Curcumin on olfactory bulbectomy effects on locomotion/exploration/rearing, rsponse to stress and hippocampal and cortical dopamine, norepinephrine and serotonin levels in rats
  Chang, X., Wang L., Li J., Wu D. - 2016

  EPINEPHRINE AND NOREPINEPHRINE   EXPLORATORY ACTIVITY   AVOIDANCE   CENTRAL NERVOUS SYSTEM LESIONS   CEREBRAL CORTEX   DOPAMINE   STEROTYPED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   SEROTONIN   STRESS
Contained in: Brain Res., 2016: 1643, 1-9

Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death

Authors: Wang, X., Hu X., Yang Y., Takata T., Sakurai T.

  Nicotinamide mononucleotide on intracerebroventricular amyloid β oligomers effects on Morris water maze performance and hippocampal long-term potentiation and neurodegeneration in rats
  Wang, X., Hu X., Yang Y., Takata T., Sakurai T. - 2016

  EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   NOOTROPICS
Contained in: Neurosci. Lett., 2016: 627, 185-191

Protective effect of lycopene on high-fat diet-induced cognitive impairment in rats

Authors: Wang, Z., Fan J., Wang J., Li Y., Xiao L., Duan D., Wang Q.

  Lycopene on high-fat diet-induced hippocampal neuron damage, plasticity, exploratory activity, Morris water maze performance and object recognition impairment in rats
  Wang, Z., Fan J., Wang J., Li Y., Xiao L., Duan D., Wang Q. - 2016

  EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   FEEDING AND DRINKING   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   NEUROGENESIS AND PLASTICITY
Contained in: Neurobiol. Learn. Mem., 2016: 131, 131-136

Protective effects of resveratrol on aging-induced cognitive impairment in rats

Authors: Gocmez, S.S., Gacar N., Utkan T., Gacar T., Scarpace P.J., Tumer N.

  Resveratrol and aging on locomotor activity, passive avoidance, Morris water maze and plasma and hippocampal tumor necrosis factor α and interleukin-1β protein levels in rats
  Gocmez, S.S., Gacar N., Utkan T., Gacar T., Scarpace P.J., Tumer N. - 2016

  LOCOMOTOR ACTIVITY   AVOIDANCE   SPATIAL ORIENTATION AND SPATIAL MEMORY   AGE   NOOTROPICS   PROTEINS AND GENES
Contained in: Pharmacol. Biochem. Behav., 2016: 142, 85-90

The memory enhancing effect of erucic acid on scopolamine-induced cognitive impairment in mice

Authors: Kim, E., Ko H.J., Jeon S.J., Lee S., Lee H.E., Kim H.N., Woo E.-R., Ryu J.H.

  Euric acid on spatial learning and passive avoidance in normal and scopolamine-treated mice: hippocampal extracellular signal-regulated kinase and CREB modulation
  Kim, E., Ko H.J., Jeon S.J., Lee S., Lee H.E., Kim H.N., Woo E.-R., Ryu J.H. - 2016

  AVOIDANCE   ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   GENDER   NOOTROPICS   PROTEIN KINASES   PROTEINS AND GENES
Contained in: Neurobiol. Learn. Mem., 2016: 131, 46-55

GPR40 receptor activation leads to CREB phosphorylation and improves cognitive performance in an Alzheimer's disease mouse model

Authors: Khan, M.Z., Zhuang X., He L.

  GPR40 receptor role in hippocampal CREB expression and nerve growth factor, brain derived neurotrophic factor and neurotrophin 3/4 levels , intracerebroventricular amyloid β1-42 on hole-board test, Morris water maze, passive avoidance and object recognition impairment in mice
  Khan, M.Z., Zhuang X., He L. - 2016

  AVOIDANCE   SPATIAL ORIENTATION AND SPATIAL MEMORY   NEUROTROPHIC FACTORS   NOOTROPICS   PROTEINS AND GENES