2015

Contained in: Neuropharmacology, 2015: 88, 180-186

The benzodiazepine midazolam acts on the expression of the defensive behavior, but not on the processing of aversive information, produced by exposure to the elevated plus maze and electrical stimulations applied to the inferior colliculus of rats

Authors: Saito, V.M., Brandao M.L.

  Exploration and inferior colliculus electrical stimulation on fear response in rats: midazolam local microinjection effects
  Saito, V.M., Brandao M.L. - 2015

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   FEAR AND RELATED BEHAVIORS   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION
Contained in: Psychopharmacology, 2015: 232, 663-672

Anxiolytic effects of ketamine in animal models of posttraumatic stress disorder

Authors: Zhang, L.-M., Zhou W.-W., Ji Y.-J., Li Y., Zhao N., Chen H.-X., Xue R., Mei X.-G., Zhang Y.-Z., Wang H.-L., Li Y.-F.

  Ketamine on response to stress, locomotion/exploration, fear conditioning and hippocampal brain derived neurotrophic factor in mice
  Zhang, L.-M., Zhou W.-W., Ji Y.-J., Li Y., Zhao N., Chen H.-X., Xue R., Mei X.-G., Zhang Y.-Z., Wang H.-L., Li Y.-F. - 2015

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   N-METHYL-D-ASPARTATE (NMDA)   STRESS
Contained in: Behav. Brain Res., 2015: 292, 316-322

The voltage-gated sodium channel activator veratrine induces anxiogenic-like behaviors in rats

Authors: Saitoh, A., Makino Y., Hashimoto T., Yamada M., Gotoh L., Sugiyama A., Ohashi M., Tsukagoshi M., Oka J.-I., Yamada M.

  Veratrine, riluzale and diazepam on exploratory activity and response to stress in rats
  Saitoh, A., Makino Y., Hashimoto T., Yamada M., Gotoh L., Sugiyama A., Ohashi M., Tsukagoshi M., Oka J.-I., Yamada M. - 2015

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   DARK/LIGHT CONTEXT   GLUCOCORTICOIDS   GLUTAMATE   STRESS
Contained in: Behav. Brain Res., 2015: 292, 537-546

Ketamine induces anxiolytic effects in adult zebrafish: a multivariate statistics approach

Authors: De Campos, E.G., Bruni A.T., De Martinis B.S.

  Ketamine on exploratory activity in zebrafishes
  De Campos, E.G., Bruni A.T., De Martinis B.S. - 2015

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   DARK/LIGHT CONTEXT   N-METHYL-D-ASPARTATE (NMDA)
Contained in: Behav. Brain Res., 2015: 294, 123-130

The light spot test: measuring anxiety in mice in an automated home-cage environment

Authors: Aarts, E., Maroteaux G., Loos M., KoopmansB., Kavacevic J., Smit A.B., Verhage M., van der Sluis S., The Neuro-BSIK Mouse Phenomics Consortium

  Environmental light spot and exploratory activity in mice: diazepam effects
  Aarts, E., Maroteaux G., Loos M., KoopmansB., Kavacevic J., Smit A.B., Verhage M., van der Sluis S., The Neuro-BSIK Mouse Phenomics Consortium - 2015

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   LUMINANCE AND VISION   STRESS
Contained in: Behav. Brain Res., 2015: 294, 131-140

Higher detection sensitivity of anxiolytic effects of diazepam by ledge-free open arm with opaque walled closed arm elevated plus maze in male rats

Authors: Horii, Y., Kawaguchi M.

  Opaqueness/transparency of ewalls in elevated plus maze on exploratory activity and anxiety behavior in rats - Methods
  Horii, Y., Kawaguchi M. - 2015

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   METHODS IN NEUROSCIENCE AND BEHAVIOR
Contained in: Neuropharmacology, 2015: 95, 226-233

Effects of lorazepam and WAY-200070 in larval zebrafish light/dark choice test

Authors: Chen, F., Chen S., Liu S., Zhang C., Peng G.

  Estradiol and lorazepam on light-dark exploration and hypothalamic c-fos expression in zebrafish larvae
  Chen, F., Chen S., Liu S., Zhang C., Peng G. - 2015

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   DARK/LIGHT CONTEXT   GONADAL HORMONES   HYPOTHALAMUS   PROTEINS AND GENES
Contained in: Pharmacol. Biochem. Behav., 2015: 138, 111-116

The nitric oxide donor molsidomine induces anxiolytic-like behaviour in two different rat models of anxiety

Authors: Kalouda, T., Pitsikas N.

  Nitric oxide donor molsidomine and diazepam effects on locomotion/exploration in rats
  Kalouda, T., Pitsikas N. - 2015

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   DARK/LIGHT CONTEXT   NITRIC AND NITROUS OXIDE
Contained in: Neuropharmacology, 2015: 97, 322-328

Systemic administration of riluzole enhances recognition memory and facilitates extinction of fear memory in rats

Authors: Sugiyama, A., Saitoh A., Inagaki M., Oka J.-I., Yamada M.

  Riluzole, D-cycloserine and diazepam on object recognition learning, fear conditioning reconsolidation and extinction in rats
  Sugiyama, A., Saitoh A., Inagaki M., Oka J.-I., Yamada M. - 2015

  ANXIOLYTIC DRUGS   EXTINCTION   FEAR AND RELATED BEHAVIORS   N-METHYL-D-ASPARTATE (NMDA)
Contained in: J. Neurosci., 2015: 35, 15847-15859

Disruption of epithalamic left-right asymmetry increases anxiety in zebrafish

Authors: Facchin, L., Duboué E.R., Halpern M.E.

  Epithalamus asymmetry and exploratory behavior in zebrafishes: cortisol level and buspirone exposure effects
  Facchin, L., Duboué E.R., Halpern M.E. - 2016

  ANXIOLYTIC DRUGS   LATERALITY AND ASYMMETRICAL INTERVENTIONS   EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY
Contained in: Learn. Mem., 2015: 22, 385-400

Prediction error and trace dominance determine the fate of fear memories after post-training manipulations

Authors: Alfei, J.M., Monti R.I.F., Molina V.A., Bueno A.M., Urcelay G.P.

  Midazolam on reinforced and non-reinforced fear conditioning reactivation effects in rats
  Alfei, J.M., Monti R.I.F., Molina V.A., Bueno A.M., Urcelay G.P. - 2015

  ANXIOLYTIC DRUGS   FEAR AND RELATED BEHAVIORS   RECALL AND RECONSOLIDATION

2014

Contained in: Brain Res., 2014: 1575, 45-54

The extra-adrenal effects of metyrapone and oxasepam on ongoing cocaine self-administration

Authors: Guerin, G.F., Schmoutz C.D., Goeders N.E.

  Metyrapone and oxasepam on cocaine self-administration in adrenalectomized and control rats
  Guerin, G.F., Schmoutz C.D., Goeders N.E. - 2014

  ADRENO-CORTICO-TROPIC-HORMONE (ACTH)   ANXIOLYTIC DRUGS   PITUITARY-ADRENAL AXIS   OPERANT CONDITIONING   EXTINCTION   GLUCOCORTICOIDS
Contained in: Pharmacol. Biochem. Behav., 2014: 118, 79-86

Excitatory/inhibitoryequilibrium of the central amygdala nucleus gates anti-depressive and anxiolytic states in the hamster

Authors: Alò, R., Avolio E., Mele M., Storino F., Canonaco A., Carelli A., Canonaco M.

  Intra-amygdala AMPA antagonist and GABA-A agonist on response to stress and exploratory activity in hamsters
  Alò, R., Avolio E., Mele M., Storino F., Canonaco A., Carelli A., Canonaco M. - 2014

  AMYGDALA   ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   γ-AMINO-BUTYRIC ACID (GABA)   GLUTAMATE   STRESS
Contained in: Behav. Brain Res., 2014: 270, 68-74

Sex differences in diazepam effects and parvalbumin-positive GABA neurons in trait anxiety Long Evans rats

Authors: Ravenelle, R., Neugebauer N.M., Niedzielak T., Donaldson S.T.

  Amygdala, putamen and hippocampus parvalbumin-positive GABAergic neurons and diazepam effects on exploratory activity in male and female rats
  Ravenelle, R., Neugebauer N.M., Niedzielak T., Donaldson S.T. - 2014

  AMYGDALA   ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   GENDER   γ-AMINO-BUTYRIC ACID (GABA)   HIPPOCAMPUS, FORNIX AND SUBICULUM   STRIATUM
Contained in: Pharmacol. Biochem. Behav., 2014: 116, 69-74

Effect of post-training administration of cocaine, diazepam and their combination on a win-stay task

Authors: Cloke, J.M., Rkieh N., Leri F.

  Cocaine and diazepam on spatial memory consolidation in rats
  Cloke, J.M., Rkieh N., Leri F. - 2014

  ANXIOLYTIC DRUGS   SPATIAL ORIENTATION AND SPATIAL MEMORY   DOPAMINE   CONSOLIDATION
Contained in: Pharmacol. Biochem. Behav., 2014: 116, 96-106

Memory interfering effects of chlordiazepoxide on consummatory successive negative contrast

Authors: Ortega, L.A., Glueck A.C., Daniel A.M., Prado-Rivera M.A., White M.M., Papini M.R.

  Chlordiazepoxide on appetitive operant conditioning consolidation in rats of different strains
  Ortega, L.A., Glueck A.C., Daniel A.M., Prado-Rivera M.A., White M.M., Papini M.R. - 2014

  ANXIOLYTIC DRUGS   OPERANT CONDITIONING   STRAIN   CONSOLIDATION
Contained in: Pharmacol. Biochem. Behav., 2014: 11, 40-46

A possible mechanism for the anxiolytic-like effect of gallic acid in the rat elevated plus maze

Authors: Mansouri, M.T., Soltani M., Naghizadeh B., Farbood Y., Mashak A., Sarkaki A.

  Serotonin antagonist, GABA agonist and antagonist and buspirone effects on locomotion/exploration in rats
  Mansouri, M.T., Soltani M., Naghizadeh B., Farbood Y., Mashak A., Sarkaki A. - 2014

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   γ-AMINO-BUTYRIC ACID (GABA)   SEROTONIN
Contained in: Brain Res., 2014: 1554, 36-48

Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: the approximated activated of receptor subtypes may explain behavioral effects

Authors: Obradovic, A.Lj., Joksimovic S., Poe M.M., Ramerstorfer J., Varagic Z., Namjoshi O., Batinic B., Radulovic T., Markovic B., Roth B.L., Sieghart W., Cook J.M., Savic M.M.

  Sh-I-048A an diazepam on exploratory/locomotor activity and spatial learning in rats
  Obradovic, A.Lj., Joksimovic S., Poe M.M., Ramerstorfer J., Varagic Z., Namjoshi O., Batinic B., Radulovic T., Markovic B., Roth B.L., Sieghart W., Cook J.M., Savic M.M. - 2014

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   γ-AMINO-BUTYRIC ACID (GABA)
Contained in: Brain Res., 2014: 1555, 28-35

Central α- and β-thujone: similar anxiogenic-like effects and differential modulation on GABAA receptors in neonatal chicks

Authors: Rivera, E.M., Cid M.P., Zunino P., Baiardi G., Salvatierra N.A.

  Intracerebroventricular GABA-A antagonist on locomotion in chicks
  Rivera, E.M., Cid M.P., Zunino P., Baiardi G., Salvatierra N.A. - 2014

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   γ-AMINO-BUTYRIC ACID (GABA)
Contained in: Learn. Mem., 2014: 21, 785-793

Memory destabilization is critical for the success of the reactivation-extinction procedure

Authors: Pineyro, M.E., Ferrer Monti R.I., Alfei J.M., Bueno A.M., Urcelay G.P.

  Fear conditionint trace reactivation on subcessive extinction procedure effects in rats: midazolam treatment effects
  Pineyro, M.E., Ferrer Monti R.I., Alfei J.M., Bueno A.M., Urcelay G.P. - 2014

  ANXIOLYTIC DRUGS   EXTINCTION   FEAR AND RELATED BEHAVIORS   RECALL AND RECONSOLIDATION
Contained in: Hippocampus, 2014: 24, 615-627

Behavioral anxiolysis without reduction of hippocampal theta frequency after histamine application in the lateral septum of rats

Authors: Chee, S.-S.A., Menard J.L., Dringenberg L.I.C.

  Intra-lateral septum histone on hippocampal theta activity, neophobia and exploratory activity in rats: buspirone effects
  Chee, S.-S.A., Menard J.L., Dringenberg L.I.C. - 2014

  ANXIOLYTIC DRUGS   HIPPOCAMPUS, FORNIX AND SUBICULUM   HISTAMINE   NEOPHOBIA   SEPTUM   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION
Contained in: Brani Res. Bull., 2014: 104, 1-6

Duration of treatment and activation of α1-containing GABAA receptors variably affect the level of anxiety and seizure susceptibility after diazepam withdrawal in rats

Authors: Kovacevic, J., Timic T., Tiruveedhula V.V., Batinic B., Namjoshi O.A., Milic M., Joksimovic S., Cook J.M., Savic M.M.

  Diazepam and pentylentetrazole-induced seizures and exploratory activity in rats
  Kovacevic, J., Timic T., Tiruveedhula V.V., Batinic B., Namjoshi O.A., Milic M., Joksimovic S., Cook J.M., Savic M.M. - 2014

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   γ-AMINO-BUTYRIC ACID (GABA)
Contained in: Physiol. Behav., 2014: 130, 91-98

NCS-1 deficiency causes anxiety and depressive-like behavior with impaired non-aversive memory in mice

Authors: De Rezende, V.B., Rosa D.V., Comin C.M., Magno L.A.V., Rodrigues A.L.S., Vidigal P., Jeromin A., Quevedo J., Romano-Silva M.A.

  Neuronal calcium sensor-1 protein on exploratory activity, social interaction, object recognition, passive avoidance and response to stress in mice: diazepam and imipramine effects
  De Rezende, V.B., Rosa D.V., Comin C.M., Magno L.A.V., Rodrigues A.L.S., Vidigal P., Jeromin A., Quevedo J., Romano-Silva M.A. - 2014

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   AVOIDANCE   ENVIRONMENT AND SOCIAL BEHAVIOR   SEROTONIN   PROTEINS AND GENES   STRESS
Contained in: Science, 2014: 344, 1293-1297

Anxiety-like behavior in crayfish is controlled by serotonin

Authors: Fossat, P., Bacque-Cazenave J., De Deurwaerdere P., Delbecque J.-P., Cattaert D.

  Serotonin and chlordiazepoxide on exploratory behavior in crayfishes
  Fossat, P., Bacque-Cazenave J., De Deurwaerdere P., Delbecque J.-P., Cattaert D. - 2014

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   LUMINANCE AND VISION   SEROTONIN
Contained in: Behav. Brain Res., 2014: 271, 249-257

Dorsomedial hypothalamus CERF type 1 receptors selectively modulate inhibitory avoidance responses in the elevated T-maze

Authors: Silva, M.S.C.F., Pereira B.A., Cespedes I.C., Nascimento J.O.G., Bittencourt J.C., Viana M.B.

  Intra-hypothalamus corticotropin-releasing factor or corticotropin-releasing factor receptor 1 antagonist on locomotion/exploration and anxiety in rats
  Silva, M.S.C.F., Pereira B.A., Cespedes I.C., Nascimento J.O.G., Bittencourt J.C., Viana M.B. - 2014

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   CORTICO-RELEASING-FACTOR (CRF)   HYPOTHALAMUS
Contained in: Psychopharmacology, 2014: 231, 3207-3215

A comparison of cannabidiolic acid with other treatments for anticipatory nausea using a rat model of contextually elicited conditioned gaping

Authors: Rock, E.M., Limebeer C.L., Navaratnam R., Sticht M.A., Bonner N., Engeland K., Downey R., Morris H., Jackson M., Parker L.A.

  Cannabidiolic acid on fear conditioning and cannabinoids, CB1 antagonist, chlordiazepoxide and 5-HT1A antagonist on nause induced by conditioned taste aversion in rats
  Rock, E.M., Limebeer C.L., Navaratnam R., Sticht M.A., Bonner N., Engeland K., Downey R., Morris H., Jackson M., Parker L.A. - 2014

  ANXIOLYTIC DRUGS   CANNABINOIDS   FEAR AND RELATED BEHAVIORS   SEROTONIN   TASTE
Contained in: Behav. Brain Res., 2014: 273, 45-51

Influence of procedural variables on rat inhibitory avoidance and escape behaviors generated by the elevated T-maze

Authors: Pobbe, R.L.H., Lopes M.A., Vasconcelos A.T., Yamashita P.S.M., de Bortoli V.C., Zangrossi H.

  Benzodiazepines on exploratory activity in rats: pre-exposure, luminance and handling effects
  Pobbe, R.L.H., Lopes M.A., Vasconcelos A.T., Yamashita P.S.M., de Bortoli V.C., Zangrossi H. - 2014

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   HANDLING   LUMINANCE AND VISION   CONTEXTUAL PRE-EXPOSURE AND RETRAINING
Contained in: Behav. Brain Res., 2014: 274, 258-263

Genetic inactivation of midkine modulates behavioural responses to ethanol possibly by enhancing GABA(A) receptor sensitivity to GABA(A) acting drugs

Authors: Vicente-Rodriguez, M., Perez-Garcia C., Haro M., Ramos M.P., Herradon G.

  Midkine cytokine on locomotion/exploration and conditioned place preference by ethanol in mice: GABAergic modulation
  Vicente-Rodriguez, M., Perez-Garcia C., Haro M., Ramos M.P., Herradon G. - 2014

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   CLASSICAL PAVLOVIAN CONDITIONING   DOPAMINE   γ-AMINO-BUTYRIC ACID (GABA)   NEUROPEPTIDES

2013

Contained in: Pharmacol. Biochem. Behav., 2013: 103, 460-466

Morphine-induced anxiolytic-like effect in morphine-sensitized mice: involvement of ventral hippocampal nicotinic acetylcholine receptors

Authors: Rezayof, A., Assadpour S., Alijanpour S.

  Intra-hippocampal nicotinic receptor agonists and antagonists on morphine exploratory and anxiolytic effects in mice
  Rezayof, A., Assadpour S., Alijanpour S. - 2013

  ACETYLCHOLINE   ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   HIPPOCAMPUS, FORNIX AND SUBICULUM   OPIOIDS
Contained in: Brain Res., 2013: 1532, 21-31

GABA-A receptor modulators alter emotionally and hippocampal theta rhythm in an animal model of long-lasting anxiety

Authors: Ademar Hoeller, A., Duzzioni M., Duarte F.S., Leme L.R., Ramos Costa A.P., da Silva Santos E.C., de Pieri C.H., dos Santos A.A., Naime A.A., Farina M., Monteiro de Lima T.C.

  GABAergic modulation of theta rhythm activity and exploratory activity in rats
  Ademar Hoeller, A., Duzzioni M., Duarte F.S., Leme L.R., Ramos Costa A.P., da Silva Santos E.C., de Pieri C.H., dos Santos A.A., Naime A.A., Farina M., Monteiro de Lima T.C. - 2013

  ACETYLCHOLINE   ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   CEREBRAL CORTEX   γ-AMINO-BUTYRIC ACID (GABA)   HIPPOCAMPUS, FORNIX AND SUBICULUM