2016

Contained in: Science, 2016: 351, 1440-1443

Diversity in neural firing dynamics supports both rigid and learned hippocampal sequences

Authors: Grosmark, A.D., Buzsaki G.

  Hippocampal neuron firing related to sleep and exploratory orientation experience in rats
  Grosmark, A.D., Buzsaki G. - 2016

  EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROGENESIS AND PLASTICITY   SLEEP
Contained in: Neuroscience, 2016: 321, 210-221

Disruption of 5-HT1A function in adolescence but not early adulthood leads to sustained increases of anxiety

Authors: Garcia-Garcia, A.L., Meng Q., Richardson-Jones J., Dranovsky A., Leonardo E.D.

  Serotonergic functional role in body temperature, exploratory activity, neophobia, sucrose preference, response to stress and circadian corticosterone levels in adolescent and early adult mice
  Garcia-Garcia, A.L., Meng Q., Richardson-Jones J., Dranovsky A., Leonardo E.D. - 2016

  EXPLORATORY ACTIVITY   AGE   GLUCOCORTICOIDS   NEOPHOBIA   SEROTONIN   STRESS   BODY TEMPERATURE
Contained in: Brain Res. Bull., 2016: 122, 54-61

Blunted inflammation mediated by NF-κB activation in hippocampus alleviates chronic normobaric hypoxia-induced anxiety-like behavior in rats

Authors: Fan, J., Fan X., Li Y., Guo J., Xia D., Ding L., Zheng Q., Wang W., Xue F., Chen R., Liu S., Hu L., Gong Y.

  Nuclear factor-κB transcription factor inhibitor pyrrolidine dithiocarbamate on hypoxia effects on exploratory activity and hippocampal inflammatory response in rats
  Fan, J., Fan X., Li Y., Guo J., Xia D., Ding L., Zheng Q., Wang W., Xue F., Chen R., Liu S., Hu L., Gong Y. - 2016

  EXPLORATORY ACTIVITY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROPEPTIDES   PROTEINS AND GENES
Contained in: Brain Res. Bull., 2016: 122, 62-70

Involvement of NMDA receptors and L-ariginine/nitric oxide/cyclic guanosine monophosphate pathway in the antidepressant-like effects of topiramate in mice forced swimming test

Authors: Ostadhadi, S., Khan M.I., Norouzi-Javidan A., Chamanara M., Jazaeri F., Zolfaghari S., Dehpour A.-R.

  NMDA, L-arginine, sildenafil, L-NAME and MK-801 on topiramate effects on response to stress and exploratory activity in mice
  Ostadhadi, S., Khan M.I., Norouzi-Javidan A., Chamanara M., Jazaeri F., Zolfaghari S., Dehpour A.-R. - 2016

  EXPLORATORY ACTIVITY   N-METHYL-D-ASPARTATE (NMDA)   NITRIC AND NITROUS OXIDE   NOOTROPICS   STRESS
Contained in: Neurosci. Behav. Physiol., 2016: 46, 461-466

Repeated inflammation-related pain syndrome in neonatal male rats alters adaptive behavior during the adolescent period of development

Authors: Butkevich, I.P., Mikhailenko V.A., Lavrova Y.A., Ulanova N.A.

  Neonatal maternal deprivation and nociceptive stimulation on response to stress, exploratory activity and Morris water maze performance in adolescent rats
  Butkevich, I.P., Mikhailenko V.A., Lavrova Y.A., Ulanova N.A. - 2016

  EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   ENVIRONMENT AND SOCIAL BEHAVIOR   NOCICEPTION   STRESS
Contained in: Neurosci. Lett., 2016: 619, 131-136

Water column depth and light intensity modulate the zebrafish preference response in the black/white test

Authors: Cordova, S.D., dos Santos T.G., de Oliveira D.L.

  Water depth and light intensity on black-white prefrence test in zebrafishes
  Cordova, S.D., dos Santos T.G., de Oliveira D.L. - 2016

  EXPLORATORY ACTIVITY   DARK/LIGHT CONTEXT   LUMINANCE AND VISION
Contained in: Eur. J. Neurosci., 2016: 43, 979-989

Searching for cognitive enhancement in the Morris water maze: better and worse performance in D-amino acid oxidase knockout (Dao-/-) mice

Authors: Pritchett, D., Taylor A.M., Barkus C., Engle S.J., Brandon N.J., Sharp T., Foster R.G., Harrison P.J., Peirson S.N., Bannerman D.M.

  D-aminoacid oxidase role in spatial learning and exploratory activity in mice
  Pritchett, D., Taylor A.M., Barkus C., Engle S.J., Brandon N.J., Sharp T., Foster R.G., Harrison P.J., Peirson S.N., Bannerman D.M. - 2016

  EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   N-METHYL-D-ASPARTATE (NMDA)
Contained in: Psychopharmacology, 2016: 233, 1445-1454

Concentration, population, and context-dependent effects of AM251 in zebrafish

Authors: Tran, S., Chatterjee D., Facciol A., Gerlai R.

  CB1 antagonist exposure on response to stress, exploratory activity and brain dopamine/serotonin levels in zebrafishes of different strains
  Tran, S., Chatterjee D., Facciol A., Gerlai R. - 2016

  EXPLORATORY ACTIVITY   CANNABINOIDS   STRAIN   FEAR AND RELATED BEHAVIORS   STRESS
Contained in: Pharmacol. Biochem. Behav., 2016: 144, 13-19

Home tank water versus novel water differentially affect alcohol-induced locomotor activity and anxiety related behaviours in zebrafish

Authors: Tran, S., Facciol A., Gerlai R.

  Ethanol exposure and environment on locomotion/exploration in zebrafishes
  Tran, S., Facciol A., Gerlai R. - 2016

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY
Contained in: Pharmacol. Biochem. Behav., 2016: 144, 78-84

Differentail effects of a short-term high-fat diet in an animal model of depression in rats treated with the 5-HT3 receptor antagonist, ondansetron, the 5-HT3 receptor agonist, 2-methy-5-HT, and the SSRI, fluoxetine

Authors: Sumaya, I.C., Dailey D., Catlett S.L.

  Fish-fat diet on 5-HT3 agonists, antagonists and fluoxetine effects on response to stress and exploratroy activity in rats
  Sumaya, I.C., Dailey D., Catlett S.L. - 2016

  EXPLORATORY ACTIVITY   FEEDING AND DRINKING   SEROTONIN   STRESS
Contained in: Proc. Natl. Acad. Sci. USA, 2016: 113, 4500-4505

Individual differences in frontolimbic circuitry and anxiety emerge with adolescent changes in endocannabinoid signaling across species

Authors: Gee, D.G., Fetcho R.N., Jing D., Li A., Glatt C.E., Drysdale A.T., Cohen A.O., Dellarco D.V., Yang R.R., Dale A.M., Jernigan T.L., Lee F.S., Casey B.J., PING Consortium

  Endocannabinoid signaling on frontolimbic circuit functioning and emotionality/exploratory activity in humans and mice of different age
  Gee, D.G., Fetcho R.N., Jing D., Li A., Glatt C.E., Drysdale A.T., Cohen A.O., Dellarco D.V., Yang R.R., Dale A.M., Jernigan T.L., Lee F.S., Casey B.J., PING Consortium - 2016

  EXPLORATORY ACTIVITY   BRAIN IMAGING   CANNABINOIDS   CEREBRAL CORTEX   AGE
Contained in: Neurosci. Lett., 2016: 620, 33-37

Intracerebellar vermis histamine facilitates memory consolidation in the elevated T maze model

Authors: Silva-Marques, B., Gianlorenco A.C.L., Mattioli R.

  Intracerebellar vermis histamine on exploratory activity habituation consolidation in mice
  Silva-Marques, B., Gianlorenco A.C.L., Mattioli R. - 2016

  EXPLORATORY ACTIVITY   CEREBELLUM   HABITUATION AND SENSITIZATION   HISTAMINE   CONSOLIDATION
Contained in: Psychopharmacology, 2016: 233, 1739-1749

Knockdown of hippocampal cysteinyl leukotriene receptor 1 prevents depressive behavior and neuroinflammation induced by chronic mild stress in mice

Authors: Yu, X.-B., Dong R.-R., Wang H., Lin J.-R., An Y.-Q., Du Y., Tang S.-S., Hu M., Long Y., Sun H.-B., Kong L.-Y., Hong H.

  Hippocampal cysteinyl leokotriene receptor 1 on neophobia, exploratory activity, response to stress and related neuroinflammation in mice: fluoxetine exposure effects
  Yu, X.-B., Dong R.-R., Wang H., Lin J.-R., An Y.-Q., Du Y., Tang S.-S., Hu M., Long Y., Sun H.-B., Kong L.-Y., Hong H. - 2016

  EXPLORATORY ACTIVITY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEOPHOBIA   NEUROPEPTIDES   SEROTONIN   STRESS
Contained in: Physiol. Behav., 2016: 160, 59-65

Evaluating "anxiety" and social behavior in jundià (Rhamdia quelen)

Authors: Abreu, M.S., Giacomini A.C.V.V., Koakoski G., Piato A.L., Barcellos J.G.

  Stress and fluoxetiune or cotical levels, exploratory activity and social behavior in fishes
  Abreu, M.S., Giacomini A.C.V.V., Koakoski G., Piato A.L., Barcellos J.G. - 2016

  EXPLORATORY ACTIVITY   ENVIRONMENT AND SOCIAL BEHAVIOR   GLUCOCORTICOIDS   SEROTONIN   STRESS
Contained in: Behav. Brain Res., 2016: 306, 26-35

Routine handling methods affect behaviour of three-spined sticklebacks in a novel test of anxiety

Authors: Thompson, R.R.J., Paul E.S., Radford A.N., Purser J., Mendl M.

  Handling on exploratory activity in fishes
  Thompson, R.R.J., Paul E.S., Radford A.N., Purser J., Mendl M. - 2016

  EXPLORATORY ACTIVITY   DARK/LIGHT CONTEXT   HANDLING
Contained in: Behav. Brain Res., 2016: 306, 52-63

The role of the medial prefrontal cortex in upfating reward value and avoiding perseveration

Authors: Laskowski, C.S., Williams R.J., Martens K.M., Gruber A.J., Fisher K.G., Euston D.R.

  Prefrontal cortex lesions on exploratory activity and spatial learning in rats
  Laskowski, C.S., Williams R.J., Martens K.M., Gruber A.J., Fisher K.G., Euston D.R. - 2016

  EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX
Contained in: Behav. Brain Res., 2016: 306, 71-83

Substrain and light regime effects on integrated anxiety-related behavioral z-scores in male C57BL/6 mice - Hypomagnesaemia has only a small effect on avoidance behavior

Authors: Labots, M., Zheng X., Moattari G., Lozeman-van't Klooster J.G., Baars J.M:, Hesseling P., Lavrijsen M., Kirchhoff S., Ohl F., van Lith H.A.

  Mg2+-deficient diet and environmental light condition on exploratory activity and plasma corticosterone/Mg2+ levels in C57BL/6 mice of different substrains
  Labots, M., Zheng X., Moattari G., Lozeman-van't Klooster J.G., Baars J.M:, Hesseling P., Lavrijsen M., Kirchhoff S., Ohl F., van Lith H.A. - 2016

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   DARK/LIGHT CONTEXT   STRAIN   GLUCOCORTICOIDS   LUMINANCE AND VISION
Contained in: Behav. Brain Res., 2016: 306, 91-105

Predator-scent stress, ethanol consumptioc and the opioid system in an animal model of PTSD

Authors: Manjoch, H., Vainer E., Matar M., Ifergane G., Zohar J., Kaplan Z., Cohen H.

  Stress, housing condition and opioid system modulation on ethanol consumption, conditioned place preference, exploratory activity, startle reflex, unconditioned fear and hippocampal opioid receptors expression in rats
  Manjoch, H., Vainer E., Matar M., Ifergane G., Zohar J., Kaplan Z., Cohen H. - 2016

  EXPLORATORY ACTIVITY   ENVIRONMENT AND SOCIAL BEHAVIOR   CLASSICAL PAVLOVIAN CONDITIONING   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   OPIOIDS   SMELL   STARTLE REFLEX   STRESS
Contained in: Behav. Brain Res., 2016: 306, 137-145

Swertisin, a C-glucosylflavone, ameliorates scopolamine-induced memory impairment in mice with its adenosine A1 receptor antagonistic property

Authors: Lee, H.E., Jeon S.J., Ryu B., Park S.J., Ko S.Y., Lee Y., Kim E., Lee S., Kim H., Jang D.S., Ryu J.H.

  C-glucosylflavone swertisin on locomotion/exploration, scopolamine-induced passive avoidance/spatial learning impairment and cortical and hippocampal protein kinase A/CREB expression in mice: adenosine A1 receptor modulation
  Lee, H.E., Jeon S.J., Ryu B., Park S.J., Ko S.Y., Lee Y., Kim E., Lee S., Kim H., Jang D.S., Ryu J.H. - 2016

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   AVOIDANCE   ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   PROTEIN KINASES   PROTEINS AND GENES
Contained in: Eur. J. Neurosci., 2016: 43, 1006-1015

The antidepressant-like effect of chronic guanosine treatment is associated with increased hippocampal neuronal differentiation

Authors: Bettio, L.E.B., Neis V.B., Pazini F.L:, Brocardo P.S., Patten A.R., Gil-Mohapel J., Christie B.R., Rodrigues A.L.S.

  Guanosine or fluoxetine on response to stress, exploratory activity and hippocampal neuron proliferation in mice
  Bettio, L.E.B., Neis V.B., Pazini F.L:, Brocardo P.S., Patten A.R., Gil-Mohapel J., Christie B.R., Rodrigues A.L.S. - 2016

  EXPLORATORY ACTIVITY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROGENESIS AND PLASTICITY   SEROTONIN   STRESS
Contained in: Eur. J. Neurosci., 2016: 43, 1016-1033

Diffuse traumatic axonal injury in mice induced complex behavioural alterations that are normalized by neutralization of interleukin-1β

Authors: Ekmark-Lewen, S., Flygt J., Fridgeiursdottir G.A., Kiwanuka O., Hanell A., Meyerson B.J., Mir A.K., Gram H., Lewen A., Clausen F., Hillered L., Marklund N.

  Central fluid percussion injury and related interleukin-1β levels on locomotion/exploration and Morris water maze performance in mice
  Ekmark-Lewen, S., Flygt J., Fridgeiursdottir G.A., Kiwanuka O., Hanell A., Meyerson B.J., Mir A.K., Gram H., Lewen A., Clausen F., Hillered L., Marklund N. - 2016

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROPEPTIDES
Contained in: Neurosci. Res. 2016: 105, 75-79

Increased stereotypy in conditional Cxcr4 knockout mice

Authors: Cash-Padgett, T., Sawa A., Jaaro-Peled H.

  Chemokine CXCR4 gene expression on locomotion/exploration, response to stress and startle reflex in mice
  Cash-Padgett, T., Sawa A., Jaaro-Peled H. - 2016

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   PROTEINS AND GENES   STARTLE REFLEX   STRESS
Contained in: Neuroscience, 2016: 324, 321-329

Ablation of fast-spiking interneurons in the dorsal striatum, recapitulating abnormalities seen post-mortem in Tourette syndrome, produces anxiety and elevated grooming

Authors: Xu, M., Li L., Pittenger C.

  Dorsal striatal fast-spiking interneuron on locomotion/exploration, prepulse inhibition of startle reflex, fear conditioning and related grooming behavior in mice
  Xu, M., Li L., Pittenger C. - 2016

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   FEAR AND RELATED BEHAVIORS   STEROTYPED BEHAVIORS   CONDITIONED AND UNCONDITIONED INHIBITION   STARTLE REFLEX   STRIATUM
Contained in: Neuroscience, 2016: 325, 175-187

Effects of early and late neonatal bromocriptine treatment on hypothalamic neuropeptides, dopaminergic reward system and behavior of adult rats

Authors: Carvalho, J.C., Lisboa P.C., De Oliveira E., Peixoto-Silva N., Pinheiro C.R., Fraga M.C., Claudio-Neto S., Franci C.R., Manhaes A.C., Moura E.G.

  Dopaminergic bromocriptine neonatal exposure on ventral tegmental area, nucleus accumbens and dorsal striatum dopamine levels, locomotion/exploration and feeding in adult rats
  Carvalho, J.C., Lisboa P.C., De Oliveira E., Peixoto-Silva N., Pinheiro C.R., Fraga M.C., Claudio-Neto S., Franci C.R., Manhaes A.C., Moura E.G. - 2016

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   DOPAMINE   FEEDING AND DRINKING   MELANOCITE STIMULATING HORMONE (MSH) AND MELANIN   NEUROPEPTIDES   NUCLEUS ACCUMBENS   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   STRIATUM
Contained in: Neurosceinec, 2016: 326, 105-116

Effects of enriched environment on alterations in the prfrontal cortex GFAP- and S100B-immunopositive atsrocytes and behavioral deficits in MK-801-treated rats

Authors: Rahati, M., Nozari M., Eslami H., Shabani M., Basiri M.

  Environmental enrichment on exploratory activity, passive avoidance and prefrontal astroglia-associated protein impairment by MK-801 in rats
  Rahati, M., Nozari M., Eslami H., Shabani M., Basiri M. - 2016

  EXPLORATORY ACTIVITY   AVOIDANCE   ENVIRONMENT AND SOCIAL BEHAVIOR   CEREBRAL CORTEX   N-METHYL-D-ASPARTATE (NMDA)   PROTEINS AND GENES
Contained in: Neuroscience, 2016: 326, 69-83

Rolipram improves cognition, reduces anxiety- and despair-like behaviors and impacts hippocampal neuroplasticity after transient global cerebral ischemia

Authors: Soares, L.M., de Vry J., Steinbusch H.W.M., Milani H., Prickaerts J., De Oliveira R.M.W.

  Rolipram on transient cerebral ischemia effects on hippocampal plasticity and neurodegeneration, response to stress and exploratory activity in mice
  Soares, L.M., de Vry J., Steinbusch H.W.M., Milani H., Prickaerts J., De Oliveira R.M.W. - 2016

  EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   STRESS
Contained in: Neurobiol. Learn. Mem., 2016: 131, 182-191

Genetic evidence for chromosome 4 loci influencing learning and memory

Authors: Anselmi, M., Correa F.J., Santos J.R., Silva A.F., Cunha J.A., Leao A.H.F., Campelo C.L.C., Ribeiro A.M., Silva R.H., Izidio G.S.

  Chromosome 4 loci on exploratory activity, spatial learning, fear conditioning and object recognition in male and female rats of different strain
  Anselmi, M., Correa F.J., Santos J.R., Silva A.F., Cunha J.A., Leao A.H.F., Campelo C.L.C., Ribeiro A.M., Silva R.H., Izidio G.S. - 2016

  EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   STRAIN   GENDER   FEAR AND RELATED BEHAVIORS   PROTEINS AND GENES
Contained in: Proc. Natl. Acad. Sci. USA, 2016: 113, E2705-E2713

IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline

Authors: Fu, A.K.Y., Hung K.-W., Yuen M.Y.F., Zhou X., Mak D.S.Y., Chan I.C.W., Cheung T.H., Zhang B., Fu W.-Y., Liew F.Y., Ip N.Y.

  Interleukin-33 on hippocampal neuron excitability, exploratory activity and fear conditioning in APP/PS1 and control mice
  Fu, A.K.Y., Hung K.-W., Yuen M.Y.F., Zhou X., Mak D.S.Y., Chan I.C.W., Cheung T.H., Zhang B., Fu W.-Y., Liew F.Y., Ip N.Y. - 2016

  EXPLORATORY ACTIVITY   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   NEUROPEPTIDES   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION
Contained in: Physiol. Behav., 2016: 161, 38-46

Pre- and postnatal dietary protein deficiency influences anxiety, memory and social behaviour in the African striped mouse Rhabdomys

Authors: Pillay, N., Rimbach R., Rymer T.

  Pre- and post-natal dietary protein deficiency on exploratory activity, object recognition and social behavior in African striped mice
  Pillay, N., Rimbach R., Rymer T. - 2016

  EXPLORATORY ACTIVITY   AGGRESSIVE AND DEFENSIVE BEHAVIOR   ENVIRONMENT AND SOCIAL BEHAVIOR   FEEDING AND DRINKING
Contained in: Physiol. Behav., 2016: 161, 166-173

Hippocampal neurogenesis dysfunction linked to depressive-like behaviors in a neuroinflammation induced model of depression

Authors: Tang, M., Lin W., Pan Y., Guan X., Li Y.

  Intracerebroventricular lipopolysaccharide on hippocampal neurogenesis, saccharine prefrence, response to stress and exploratory activity in rats
  Tang, M., Lin W., Pan Y., Guan X., Li Y. - 2016

  EXPLORATORY ACTIVITY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROPEPTIDES   NEUROGENESIS AND PLASTICITY   STRESS