Themes: AGE

2012

Contained in: Nat. Rev. Neurosci., 2012: 13, 240-250

The ageing cortical synapse: hallmarks and implications for cognitive decline

Authors: Morrison, J.H., Baxter M.G.

  Cortical and hippocampal synaptic aging and plasticity: oestrogen role - Review
  Morrison, J.H., Baxter M.G. - 2012

  CEREBRAL CORTEX   AGE   GONADAL HORMONES   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROGENESIS AND PLASTICITY   REVIEWS AND COMMENTARIES
Contained in: Nat. Neurosci., 2012: 15, 1184-1191

Decision-making in the adolescent brain

Authors: Blakemore, S.-J., Robbins T.W.

  Decision making in adolescent brain - Review
  Blakemore, S.-J., Robbins T.W. - 2012

  CEREBRAL CORTEX   AGE   NUCLEUS ACCUMBENS   NEUROGENESIS AND PLASTICITY   REVIEWS AND COMMENTARIES   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   STRIATUM   SUBSTANTIA NIGRA
Contained in: Proc. Natl. Acad. Sci. USA, 2012: 109, 16318-16323

Altered fear learning across development in both mouse and human

Authors: Pattwell, S.S., Duhoux S., Hartley C.A., Johnson D.C., Jing D., Elliott M.D., Ruberry E.J., Powers A., Mehta N., Yang R.R., Soliman F., Glatt C.E., Casey B.J., Ninan I., Lee F.S.

  Fear extinction in mice and humans of different age: prefrontal excitability role
  Pattwell, S.S., Duhoux S., Hartley C.A., Johnson D.C., Jing D., Elliott M.D., Ruberry E.J., Powers A., Mehta N., Yang R.R., Soliman F., Glatt C.E., Casey B.J., Ninan I., Lee F.S. - 2012

  CEREBRAL CORTEX   AGE   EXTINCTION   FEAR AND RELATED BEHAVIORS
Contained in: Neurosci. Lett., 2012: 529, 155-160

Protective role of vitamin E and C against oxidative stress caused by intermittent cold exposure in aging rat's frontoparietal cortex

Authors: Devi, S.A., Manjula K.R., Subramanyam M.V.V.

  Vitamin E and C on intermittent cold exposure stress in rats of different age: fronto-parietal oxidative stress effects
  Devi, S.A., Manjula K.R., Subramanyam M.V.V. - 2012

  CEREBRAL CORTEX   AGE   FEEDING AND DRINKING   STRESS   BODY TEMPERATURE
Contained in: Exp. Brain Res., 2012: 216, 35-40

Compromised encoding of proprioceptively determined joint angles in older adults: the role of working memory and attentional load

Authors: Goble, D.J., Mousigian M.A., Brown S.H.

  Proprioception and attention/working memory in humans
  Goble, D.J., Mousigian M.A., Brown S.H. - 2012

  AGE
Contained in: Proc. Natl. Acad. Sci. USA, 2012: 109, 4290-4295

Development of GABAergic inputs controls the contribution of maturing neurons to the adult hippocampal network

Authors: Li, Y., Aimone J.B., Xu X., Callaway E.M., Gage F.H.

  GABAergic modulation of hippocampal excitability in mice
  Li, Y., Aimone J.B., Xu X., Callaway E.M., Gage F.H. - 2012

  AGE   γ-AMINO-BUTYRIC ACID (GABA)   HIPPOCAMPUS, FORNIX AND SUBICULUM   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION
Contained in: Behav. Brain Res., 2012: 230, 158-166

Increased sensitivity to alcohol induced changes in ERK MAP kinase phosphorylation and memory disruption in adolescent as compared to adult C57BL/6J mice

Authors: Spanos, M., Besheer J., Hodge C.W.

  Sensitivity to alcohol on brain extracellular signal-regulated kinase expression and object recognition in mice of different age
  Spanos, M., Besheer J., Hodge C.W. - 2012

  AGE   PROTEIN KINASES
Contained in: Neurosci. Lett., 2012: 516,161-165

Hippocampal calbindin-1 immunoreactivity correlate of recognition memory performance in aged mice

Authors: Soontornniyomkij, V., Risbrough V.B., Young J.W., Soontornniyomkij B., Jeste D.V., Achim C.L.

  Hippocampal calbindin-1 expression on recognition memory in young and aged mice
  Soontornniyomkij, V., Risbrough V.B., Young J.W., Soontornniyomkij B., Jeste D.V., Achim C.L. - 2012

  AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM
Contained in: Physiol. Behav., 2012: 106, 417-422

Flavor learning in weanling rats and its retention

Authors: Ueji, K., Yamamoto T.

  Ontogeny of flavour learning in rats
  Ueji, K., Yamamoto T. - 2012

  AGE   TASTE
Contained in: Nat. Neurosci., 2012: 15, 1111-1113

Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities

Authors: Oliveira, A.M.M., Hemstedt T.J., Bading H.

  Hippocampal Dnmt3a2 gene expression and cognition in mice of different age: NMDA modulation
  Oliveira, A.M.M., Hemstedt T.J., Bading H. - 2012

  AGE   FEAR AND RELATED BEHAVIORS   γ-AMINO-BUTYRIC ACID (GABA)   HIPPOCAMPUS, FORNIX AND SUBICULUM   N-METHYL-D-ASPARTATE (NMDA)   PROTEINS AND GENES
Contained in: Neurosci. Lett., 2012: 530, 53-58

Melatonin supplementation delays the decline of adult hippocampal neurogenesis during normal aging of mice

Authors: Ramirez-Rodriguez, G., Vega-Rivera N.M., Benitez-King G., Castro-Garcia M., Ortiz-Lopez L.

  Melatonin on hippocampal adult neurogenesis in mice of different age
  Ramirez-Rodriguez, G., Vega-Rivera N.M., Benitez-King G., Castro-Garcia M., Ortiz-Lopez L. - 2012

  AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM   MELATONIN   NEUROGENESIS AND PLASTICITY

2011

Contained in: Behav. Brain Res., 2011: 216, 136-145

Prefrontal cortex, calorie restriction and stress during aging: studies on dopamine and acetylcholine release, BDNF and working memory

Authors: Del Arco, A., Segovia G., de Blas M., Garrido P., Acuna-Castroviejo D., Pamplona R., Mora F.

  Caloric restriction on response to stress, locomotion, learning and prefrontal acetylcholine, dopamine and BDNF in aged rats
  Del Arco, A., Segovia G., de Blas M., Garrido P., Acuna-Castroviejo D., Pamplona R., Mora F. - 2011

  ACETYLCHOLINE   AMYGDALA   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   AGE   DOPAMINE   FEEDING AND DRINKING   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   STRESS
Contained in: Behav. Brain Res., 2011: 219, 197-204

Memory enhancing effects of saffron in aged mice are correlated with antioxidant protection

Authors: Papandreou, M.A., Tsachaki M., Efthimiopoulos S., Cordopatis P., Lamari F.N., Margarity M.

  Effects of saffron extract on passive avoidance, brain acetylcholinesterase and antioxidant activity in adult and aged mice
  Papandreou, M.A., Tsachaki M., Efthimiopoulos S., Cordopatis P., Lamari F.N., Margarity M. - 2011

  ACETYLCHOLINE   AVOIDANCE   AGE   NOOTROPICS
Contained in: Neuroscience, 2011: 197, 280-292

The coumarin scopoletin potentiates acetylcholine release from synaptosomes, amplifies hippocampal long-term potentiation and ameliorates anticholinergic- and age-impaired memory

Authors: Hornick, A., Lieb A., Vo N.P., Rollinger J.M., Stuppner H., Prast H.

  Acetylcholinesterase inhibitor, nicotinic acetylcholine receptor agonists and antagonists on hippocampal long-term potenttiation in mice. Intracerebroventricular acetylcholinesterase inhibition on locomotion/exploration, T-maze and object recognition in adult and old mice
  Hornick, A., Lieb A., Vo N.P., Rollinger J.M., Stuppner H., Prast H. - 2011

  ACETYLCHOLINE   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   N-METHYL-D-ASPARTATE (NMDA)
Contained in: Brain Res., 2011: 1371, 150-160

Long-term social isolation exacerbates the impairment of spatial working memory in APP/PS1 transgenic mice

Authors: Huang, H.-J., Liang K.-C., Ke H.-C., Chang Y.-Y., Hsieh-Li H.M.

  Social isolation on Aβ-amyloid-induced learning and neuronal impairment in mice of different age
  Huang, H.-J., Liang K.-C., Ke H.-C., Chang Y.-Y., Hsieh-Li H.M. - 2011

  EPINEPHRINE AND NOREPINEPHRINE   ACETYLCHOLINE   AMYGDALA   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   ENVIRONMENT AND SOCIAL BEHAVIOR   AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM   N-METHYL-D-ASPARTATE (NMDA)   SEROTONIN
Contained in: Neuropharmacology, 2011: 60, 223-234

Chronic treatment with the α2-adrenoceptor antagonist fluparoxan prevents age-relateddeficits in spatial working memory in APPxPS1 transgenic mice without altering β-amyloid plaque load or astrocytosis

Authors: Scullion, G.A., Kendall D.A., Marsden C.A., Sunter D., Pardon M.-C.

  α2-adrenergic antagonist on brain β-amyloid, locomotory and cognitive deficit by aging in mice
  Scullion, G.A., Kendall D.A., Marsden C.A., Sunter D., Pardon M.-C. - 2011

  EPINEPHRINE AND NOREPINEPHRINE   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   AGE   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM
Contained in: Neurobiol. Learn. Mem., 2011: 96, 166-172

Norepinephrine mediates contextual fear learning and hippocampal pCREB in juvenile rats exposed to predator odor

Authors: Kabitzke, P.A., Silva L., Wiedenmayer C.

  Propranolol on unconditioned and conditioned fear and related hippocampal CREB expression in infant and juvenile rats
  Kabitzke, P.A., Silva L., Wiedenmayer C. - 2011

  EPINEPHRINE AND NOREPINEPHRINE   AGE   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   SMELL   PROTEINS AND GENES
Contained in: Proc. Natl. Acad. Sci. USA, 2011: 108, 1182-1187

Selective early-acquired fear memories undergo temporary suppression during adolescence

Authors: Pattwell, S.S., Bath K.G., Casey B.J., Ninan I., Lee F.S.

  Object recognition and fear memory at different age in mice: role of hippocampal phosphatidylinositol-3 kinase/mitogen-activated protein kinase and amygdalar excitability
  Pattwell, S.S., Bath K.G., Casey B.J., Ninan I., Lee F.S. - 2011

  AMYGDALA   PERIRHINAL CORTEX   AGE   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   PROTEIN KINASES   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION
Contained in: Neurosci. Lett., 2011: 499, 93-98

Multi-decade hippocampal and amygdala volume analysis: equal variability and limited age effect

Authors: Mouiha, A., Duchesne S.

  Age and sex on hippocampal and amygdalar volume in humans
  Mouiha, A., Duchesne S. - 2011

  AMYGDALA   AGE   GENDER   HIPPOCAMPUS, FORNIX AND SUBICULUM
Contained in: Behav. Brain Res., 2011: 225, 192-200

Age increases anxiety and reactivity of the fear/anxiety circuit in Lewis rats

Authors: Meyza, K.Z., Boguszewski P.M., Nikolaev E., Zagrodzka J.

  Exploration and response to stress on amygdalar, hippocampal and hypothalamic c-fos expression in rats of different age
  Meyza, K.Z., Boguszewski P.M., Nikolaev E., Zagrodzka J. - 2011

  AMYGDALA   EXPLORATORY ACTIVITY   AGE   LUMINANCE AND VISION   HYPOTHALAMUS   HIPPOCAMPUS, FORNIX AND SUBICULUM   PROTEINS AND GENES   STRESS
Contained in: J. Neurosci., 2011: 31, 4991-4999

The role of the medial prefrontal cortex in innate fear regulation in infants, juvenile, and adolescents

Authors: Chan, T., Kyere K., Davis B.R., Shemyakin A., Kabitzke P.A., Shair H.N., Barr G.A., Wiedenmayer C.P.

  Prefrontal role on innate fear and prefrontal, amygdalar and periaqueductal c-fos expression in male and female rats of different ages
  Chan, T., Kyere K., Davis B.R., Shemyakin A., Kabitzke P.A., Shair H.N., Barr G.A., Wiedenmayer C.P. - 2011

  AMYGDALA   NEURAL REVERSIBLE INACTIVATIONS   CEREBRAL CORTEX   AGE   GENDER   FEAR AND RELATED BEHAVIORS   PROTEINS AND GENES
Contained in: J. Neurosci., 2011: 31, 13157-13167

Feedback timing modulates brain systems for learning in humans

Authors: Foerde, K., Shohamy D.

  Operant conditioning in Parkinson's disease and control humans of different age
  Foerde, K., Shohamy D. - 2011

  AMYGDALA   LATERALITY AND ASYMMETRICAL INTERVENTIONS   BRAIN IMAGING   CENTRAL NERVOUS SYSTEM LESIONS   OPERANT CONDITIONING   PERIRHINAL CORTEX   CEREBRAL CORTEX   AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM   STRIATUM   SUBSTANTIA NIGRA
Contained in: Hippocampus, 2011: 21, 461-466

A medial temporal lobe division of labor: insights from memory in aging and early Alzheimer disease

Authors: Wolk, D.A., Dunfee K.L., Dickerson B.C., Aizenstein H.J., DeKosky S.T.

  Medial temporal lobe and memory in aging and early Alzheimer disease subjects
  Wolk, D.A., Dunfee K.L., Dickerson B.C., Aizenstein H.J., DeKosky S.T. - 2011

  LATERALITY AND ASYMMETRICAL INTERVENTIONS   CENTRAL NERVOUS SYSTEM LESIONS   ENTORHINAL CORTEX   PERIRHINAL CORTEX   CEREBRAL CORTEX   AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM
Contained in: Proc. Natl. Acad. Sci. USA, 2011: 108, 7212-7217

Deficit in switching between functional brain networks underlies the impact of multitasking on working memory in older adults

Authors: Clapp, W.C., Rubens M.T., Sabharwal J., Gazzaley A.

  Functional brain networks during working memory in younger and older adult humans
  Clapp, W.C., Rubens M.T., Sabharwal J., Gazzaley A. - 2011

  LATERALITY AND ASYMMETRICAL INTERVENTIONS   BRAIN IMAGING   PERIRHINAL CORTEX   CEREBRAL CORTEX   AGE
Contained in: Hippocampus, 2011: 21, 531-646

Deafferentation enhances neurogenesis in the young and middle aged hippocampus but not in the aged hippocampus

Authors: Shetty, A.K., Hattiangady B., Rao M.S., Shuai B.

  Unilateral hippocampal deafferentation on neurogenesis and plasticity in rats of different age
  Shetty, A.K., Hattiangady B., Rao M.S., Shuai B. - 2011

  LATERALITY AND ASYMMETRICAL INTERVENTIONS   CENTRAL NERVOUS SYSTEM LESIONS   AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROGENESIS AND PLASTICITY
Contained in: Hippocampus, 2011: 21, 803-814

Functional phenotyping of successful aging in long-term memory: preserved performance in the absence of neural compensation

Authors: Duzel, E., Schutze H., Yonelinas A.P., Heinze H.-J.

  Brain activity during encoding in young and aged humans
  Duzel, E., Schutze H., Yonelinas A.P., Heinze H.-J. - 2011

  LATERALITY AND ASYMMETRICAL INTERVENTIONS   BRAIN IMAGING   AGE
Contained in: Behav. Brain Res., 2011: 225, 160-168

Age differences in spatial working memory contributions to visuomotor adaptation and transfer

Authors: Langan, J., Seidler R.D.

  Age differences in spatial working memory and brain activity in humans
  Langan, J., Seidler R.D. - 2011

  LATERALITY AND ASYMMETRICAL INTERVENTIONS   BRAIN IMAGING   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   AGE
Contained in: J. Neurosci., 2011: 31, 10882-10890

Heritability of working memory brain activation

Authors: Blokland, G.A.M., McHanon K.L., Thompson P.M., Martin N.G., de Zubicaray G.I., Wright M.J.

  Age and sex on brain activation during working memory in humans
  Blokland, G.A.M., McHanon K.L., Thompson P.M., Martin N.G., de Zubicaray G.I., Wright M.J. - 2011

  LATERALITY AND ASYMMETRICAL INTERVENTIONS   BRAIN IMAGING   CEREBRAL CORTEX   AGE   GENDER
Contained in: J. Neurosci., 2011: 31, 13236-13245

Frontotemporal connections in episodic memory and aging: a diffusion MRI tractography study

Authors: Metzler-Baddeley, C., Jones D.K., Belaroussi B., Aggleton J.P., O'Sullivan M.J.

  Age and brain activity during object location in humans
  Metzler-Baddeley, C., Jones D.K., Belaroussi B., Aggleton J.P., O'Sullivan M.J. - 2011

  LATERALITY AND ASYMMETRICAL INTERVENTIONS   BRAIN IMAGING   SPATIAL ORIENTATION AND SPATIAL MEMORY   PERIRHINAL CORTEX   CEREBRAL CORTEX   AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM
Contained in: J. Neurosci., 2011: 31, 14284-14290

Caudate dopamine D1 receptor density is associated with individual differences in frontoparietal connectivity during working memory

Authors: Rieckmann, A., Karlsson S., Fischer H., Backman L.

  Caudate D1 receptor density on fronto-parietal activity during working memory in humans
  Rieckmann, A., Karlsson S., Fischer H., Backman L. - 2011

  LATERALITY AND ASYMMETRICAL INTERVENTIONS   BRAIN IMAGING   CEREBRAL CORTEX   AGE   STRIATUM