Search
2018
Peptides acting as cognitive enhancers
Authors: Asua, D., Bougamra G., Calleja-Felipe M., Morales M., Knafo S. FGL, PTD4-PI3KAc and PTEN peptides on learning and memory improvement - Review
Asua, D., Bougamra G., Calleja-Felipe M., Morales M., Knafo S. - 2018
Memory retrieval re-activates Erk1/2 signaling in the same set of CA1 neurons recruited during conditioning
Authors: Zamorano, C., Fernandez-Albert J., Storm D.R., Carné X., Sindreu C. Hippocampal extracellular signal-regulated kinase signaling related on contextual fear conditioning retrieval/reconsolidation and effects on basolateral amygdala c-fos expression in mice
Zamorano, C., Fernandez-Albert J., Storm D.R., Carné X., Sindreu C. - 2018
Effects of morphine on place conditioning and ERK1/2 phosphorylation in the nucleus accumbens of psychogenetically selected Roman low- and high-avoidance rats
Authors: Rosas, M., Porru S., Sabariego M., Piludu M.A., Giorgi O., Corda M.G., Acquas E. Conditioned place preference by morphine and related accumbal extracellular signal-regulated kinase 1/2 expression in Roman low- and high-avoidance rats
Rosas, M., Porru S., Sabariego M., Piludu M.A., Giorgi O., Corda M.G., Acquas E. - 2018
Xanthoceraside modulates NR2B-containing NMDA receptors at synapses and rescues learning-memory deficits in APP/PS1 transgenic mice
Authors: Zhu, L., Yang L., Zhao X., Liu D., Guo X., Liu P., Chi T., Ji X., Zou L. Xanthoceraside saponin on hippocampal neuron excitability/trophism, nest-building behavior, object recognition and Morris water maze performance in APP/PS1 and control mice
Zhu, L., Yang L., Zhao X., Liu D., Guo X., Liu P., Chi T., Ji X., Zou L. - 2018
Bidirectional modulation of glutamatergic synaptic transmission by metabotropic glutamate type 7 receptors at Schaffer collateral-CA1 hippocampal synapses
Authors: Martin, R., Ferrero J.J., Collado-Alsina A., Aguado C., Lujan R., Torres M., Sanchez-Prieto J. Glutamate type 7 receptor role in hippocampal neuron excitability in mice
Martin, R., Ferrero J.J., Collado-Alsina A., Aguado C., Lujan R., Torres M., Sanchez-Prieto J. - 2018
Integration of plasticity mechanisms within a single sensory neuron of C. elegans actuates a memory
Authors: Hawk, J.D., Calvo A.C., Liu P., Almoril-Porras A., Aljobeh A., Torruella-Suarez M.L., Ren I., Cook N., Greenwood J., Luo L., Wang Z.-W., Samuel A.D.T., Colon-Ramos D.A. Neuronal excitability/plasticity related to environmental temperature sensory information in nematodes
Hawk, J.D., Calvo A.C., Liu P., Almoril-Porras A., Aljobeh A., Torruella-Suarez M.L., Ren I., Cook N., Greenwood J., Luo L., Wang Z.-W., Samuel A.D.T., Colon-Ramos D.A. - 2018
Input-specific NMDAR-dependent potentiation of dendritic GABAergic inhibition
Authors: Chiu, C.Q., Martenson J.S., Yamazaki M., Matsume R., Sakimura K., Tomita S., Tavalin S.J., Higley M.J. NMDA modulation on GABAergic prefrontal inhibitory interneurons excitability in mice: optogenetic study
Chiu, C.Q., Martenson J.S., Yamazaki M., Matsume R., Sakimura K., Tomita S., Tavalin S.J., Higley M.J. - 2018
CAST: its molecular structure and phosphoryation-dependent regulation of presynaptic plasticity
Authors: Hamada, S., Ohtsuka T. Proteins and presynaptic plasticity - Review
Hamada, S., Ohtsuka T. - 2018
Recombinant tissue plasminogen activator induces long-term anxiety-like behaviors via the ERK1/2-GAD1-GABA cascade in the hippocampus of a rat model
Authors: Dong, M.-X., Li C.-M., Shen P., Hu Q.-C., Wei Y.-D., Ren Y.-F., Yu J., Gui S.-W., Liu Y.-Y., Pan J.-X., Xie P. Systemic recombinant tissue plasminogen activator on hippocampal extracellular signal-regulated kinase 1/2-GABA cascade, locomotion, exploration, rearing, response to stress, neophobia, sucrose preference and Morris water maze performance in rats
Dong, M.-X., Li C.-M., Shen P., Hu Q.-C., Wei Y.-D., Ren Y.-F., Yu J., Gui S.-W., Liu Y.-Y., Pan J.-X., Xie P. - 2018
Hippocampal mTOR signaling is required for the antidepressant effects of paroxetine
Authors: Xu, D., Sun Y., Wang C., Wang H., Wang Y., Zhao W., Bao G., Wang F., Cui Z., Jiang B. Hippocampal and prefrontal mammalian target of rapamycin signaling on paroxetine effects on stress-induced social interaction, sucrose preference and response to stress changes in mice
Xu, D., Sun Y., Wang C., Wang H., Wang Y., Zhao W., Bao G., Wang F., Cui Z., Jiang B. - 2018
Inhibition of Cdk5 rejuvenates inhibitory circuits and restores experience-dependent plasticity in adult visual cortex
Authors: Li, Y., Wang L., Zhang X., Huang M., Li S., Wang X., Chen L., Jiang B., Yang Y. Cyclin-dependent kinase 5 role in visual cortex neuron NR2B-GABA-A expression/excitability/plasticity in mice
Li, Y., Wang L., Zhang X., Huang M., Li S., Wang X., Chen L., Jiang B., Yang Y. - 3117
Direct pharmacological Akt activation rescues Alzheimer's disease like memory impairments and aberrant synaptic plasticity
Authors: Yi, J.H., Baek S.J., Heo S., Park H.J., Kwon H., Lee S., Jung J., Park S.J., Kim B.C., Lee Y.C., Ryu J.H., Kim D.H. Cospase 3/protein kinase B-Akt role in amyloid β-induced hippocampal long-term potentiation, object recognition, passive avoidance and spatial learning impairment in mice
Yi, J.H., Baek S.J., Heo S., Park H.J., Kwon H., Lee S., Jung J., Park S.J., Kim B.C., Lee Y.C., Ryu J.H., Kim D.H. - 2018
Estrogenic regulation of memory consolidation: a look beyond the hippocampus, ovaries, and females
Authors: Frick, K.M., Tuscher J.J., Koss W.A., Kim J., Taxier L.R. Estrogens and memory consolidation in females - Review
Frick, K.M., Tuscher J.J., Koss W.A., Kim J., Taxier L.R. - 2018
Modulation of sphingosine 1-posphatase (S1P) attenuates spatial learning and memory impairments in the valproic acid rat model of autism
Authors: Wu, H., Zhang Q., Gao J., Sun C., Wang J., Cao Y., Hao Y., Wu L. Sphingosine 1-posphatase on valproic acid-induced hippocampal apoptosis/calcium-calmodulin kinase II-CREB levels and spatial learning impariment in rats
Wu, H., Zhang Q., Gao J., Sun C., Wang J., Cao Y., Hao Y., Wu L. - 2018
Brain-region-specific molecular responses to maternbal separation and social defeat stress in mice
Authors: Sachs, B.D., Tran H.L., Folse E., Caron M.G. Early-life maternal separation and adult social defeat stress on accumbal/amygdalar/prefrontal signal transduction/gene expression in mice
Sachs, B.D., Tran H.L., Folse E., Caron M.G. - 2018
Two weeks of variable stress increases gamma-H2AX levels in the mouse bed nucleus of the stria terminalis
Authors: Hare, B.D., Thornton T.M., Rincon M., Golijanin B., King S.B., Jaworski D.M., Falls W.A. Stress on bed nucleus of the stria terminalis, prefrontal, amygdalar and hippocampal histone H2A-X/p38 mitogen-activated protein kinases/GSK3β expression in mice
Hare, B.D., Thornton T.M., Rincon M., Golijanin B., King S.B., Jaworski D.M., Falls W.A. - 2018
Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability
Authors: Lisman, J., Cooper K., Sehgal M., Silva A.J. CREB-dependent neuronal synaptic plasticity/excitability in memory processes - Review
Lisman, J., Cooper K., Sehgal M., Silva A.J. - 2018
Medial preoptic circuit induces hunting-like actions to target objects and prey
Authors: Park, S.-G., Jeong Y.-C., Kim D.-G., Lee M.-H., Shin A., Park G., Ryoo J., Hong J., Bae S., Kim C.-H., Lee P.-S., Kim D. Medial preoptic area neuron activity related to exploratory activity, aggressive, sexual and feeding behavior and spatial navigation in mice: optogenetic study
Park, S.-G., Jeong Y.-C., Kim D.-G., Lee M.-H., Shin A., Park G., Ryoo J., Hong J., Bae S., Kim C.-H., Lee P.-S., Kim D. - 2018
Insular cortex mediates approach and avoidance responses to social affective stimuli
Authors: Rogers-Carter, M.M., Varela J.A., Gribbons K.B., Pierce A.F., McGoey M.T., Ritchey M., Christianson J.P. Oxytocinergic modulation on insular cortex neuron excitability and social interaction with stressed conspecific of different age in rats: optogenetic study
Rogers-Carter, M.M., Varela J.A., Gribbons K.B., Pierce A.F., McGoey M.T., Ritchey M., Christianson J.P. - 2018
Protopanaxadiol derivative DDPU improves beavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy
Authors: Guo, X., Lv J., Lu J., Fan L., Huang X., Hu L., Wang J., Shen X. Protopanaxadiol derivative DDPU on cortical neurodegeneration, nesting behavior and Morris water maze performance in APP/PS1 mice
Guo, X., Lv J., Lu J., Fan L., Huang X., Hu L., Wang J., Shen X. - 2018
Reversible inactivation of interpeduncular nucleus impairs memory consolidation and retrieval but not learning in rats: a behavioral and molecular study
Authors: Khatami, L., Khodagholi F., Motamedi F. Interpeduncular nucelus inactivation on hippocampal CREB, c-fos p70 kinase expression, passive avoidance and Morris water maze acquisition, consolidation and retrieval in rats
Khatami, L., Khodagholi F., Motamedi F. - 2018
Dendritic structural plasticity and neuropsychiatry disease
Authors: Forrest, M.P., Parnell E., Penzes P. Dendritic spine pathology, structural plasticity and neuropsychiatric disease - Review
Forrest, M.P., Parnell E., Penzes P. - 2018
Active protection: learning-activated Raf/MAPK activity protects labile memory fron Rac1-independent forgetting
Authors: Zhang, X., Li Q., Wang L., Liu Z.-J., Zhong Y. Raf/MAPK activity related to olfactory aversive conditioning learning and memory in Drosophila: Rac1/c-AMP/Raf pathway study
Zhang, X., Li Q., Wang L., Liu Z.-J., Zhong Y. - 2018
Reduced expression of Na+/Ca2+ excahngers is associated with cognitive deficits seen in Alzheimer's disease model mice
Authors: Moriguchi, S., Kita S., Fukaya M., Osnai M., Inagaki R., Sasaki Y., Izumi H., Horie K., Takeda J., Saito T., Sakagami H., Saido T.C., Iwamoto T., Fukunaga K. Brain NCX proteins (Na+/Ca++ exchangers) expression and hippocampal excitability, plasticity, calcium calmodulin-dependent kinase activity, object recognition, passive avoidance and spatial learning in Alzheimer's disease mouse model APP mice
Moriguchi, S., Kita S., Fukaya M., Osnai M., Inagaki R., Sasaki Y., Izumi H., Horie K., Takeda J., Saito T., Sakagami H., Saido T.C., Iwamoto T., Fukunaga K. - 2018
HSP70 facilitates memory consolidation of fear conditioning through MAPK pathway in the hippocampus
Authors: Porto, R.R., Dutra F.D., Crestani A.P., Holsinger R.M.D., Quillfeldt J.A., de Bittencourt Jr. P.I.H., de Oliveira Alvares L. Hippocampal heat shock 70 proteins and mitogen-activated protein kinase/extracellular signal regulated kinase pathway role during fear conditioning consolidation in rats
Porto, R.R., Dutra F.D., Crestani A.P., Holsinger R.M.D., Quillfeldt J.A., de Bittencourt Jr. P.I.H., de Oliveira Alvares L. - 2018
Quantitative proteomic analysis reveals synaptic dysfunction in the amygdala of rats susceptible to chornic mild stress
Authors: Zhou, M., Liu Z., Yu J., Li S., Tang M., Zeng L., Wang H., Xie H., Peng L., Huang H., Zhou C., Xie P., Zhou J. Stress on amygdala proteins, calcium-calmodulin kinase II and glutamatergic receptors expression, sucrose preference and response to stress in rats
Zhou, M., Liu Z., Yu J., Li S., Tang M., Zeng L., Wang H., Xie H., Peng L., Huang H., Zhou C., Xie P., Zhou J. - 2018
Antidepression action of BDNF requires and is mimicked by Gαi1/3 expression in the hippocampus
Authors: Marshall, J., Zhou X., Chen G., Yang S., Li Y., Wang Y., Zhang Z., Jiang Q., Birnbaumer L., Cao C. Hippocampal Gα1/3 protein role in Brain-derived neurotrophic factor-TrkB signaling effects on neuronal plasticity in mice: role in response toi stress and depressive behavior
Marshall, J., Zhou X., Chen G., Yang S., Li Y., Wang Y., Zhang Z., Jiang Q., Birnbaumer L., Cao C. - 2018
GPR30 activation improves memory and facilitates DHPG-induced LTD in the hippocampal CA3 of middle-aged mice
Authors: Xu, W., Cao J., Zhou Y., Wang L., Zhu G. G protein-coupled estrogen receptor 1 (GPR1/30) role in hippocampal neuron glutamate-BDNF-TrkB signaling excitability, fear conditioning and Morris water maze performance in male and female mice of different age
Xu, W., Cao J., Zhou Y., Wang L., Zhu G. - 2018
Running exercise mitigates the negative consequences of chronic stress on dorsal hippocampal long-term potentiation in male mice
Authors: Miller, R.M., Marriott D., Trotter J., Hammond T., Lyman D., Call T., Walker B., Christensen N., Haynie D., Badura Z., Homan M., Edwards J.G. Exercise and stress on plasma corticosterone levels hippocampal neuron excitability/NMDA-AMPA-BDNF-Dopamine 1/5 receptor-TrkB-glucocorticoid receptor expression and spatial learning in mice
Miller, R.M., Marriott D., Trotter J., Hammond T., Lyman D., Call T., Walker B., Christensen N., Haynie D., Badura Z., Homan M., Edwards J.G. - 2018
Development of the fear regulation system from early adolescence to young adulthood in female mice
Authors: Matsuda, S., Matsuzawa D., Ishii D., Tomizawa H., Shimizu E. Fear conditioning acquisition and extinction development and related prefrontal/hippocampal extracellular signal-regulated kinase expression in female mice
Matsuda, S., Matsuzawa D., Ishii D., Tomizawa H., Shimizu E. - 2018