Search
2017
Effect of Salvia miltiorrhiza root extract on brain acetylcholinesterse and butyrylcholinesterase activities, their mRNA levels and memory evaluation in rats
Authors: Ozarowski, M., Mikolajczak P.L., Piasecka A., Kujawski R., Bartkowiak-Wieczorek J., Bogacz A., Szulc M., Kaminska E., Kujawska M., Gryszczynska A., Kachlicki P., Buchwald W., Klejewski A., Seremak-Mrozikiewicz A. Huperzine A and Salvia root extract on hippocampal, cortical acetyl-butyryl cholinesterase levels, locomotor activity and passive avoidance performance in scopolamine-injected and control rats
Ozarowski, M., Mikolajczak P.L., Piasecka A., Kujawski R., Bartkowiak-Wieczorek J., Bogacz A., Szulc M., Kaminska E., Kujawska M., Gryszczynska A., Kachlicki P., Buchwald W., Klejewski A., Seremak-Mrozikiewicz A. - 2017
Edaravone attenuates intracerebroventricular streptozotocin-induced cognitive impairment in rats
Authors: Reeta, K.H., Singh D., Gupta Y.K. Free radical scavenger edaravane on intracerebroventricular streptosotocin-induced hippocampal/cortical oxidative stress/acetylcholinesterase levels, passive avoidance and Morris water maze performance impairment in rats
Reeta, K.H., Singh D., Gupta Y.K. - 2017
The neuroprotective effect of memantine on methamphetamine-induced cognitive deficits
Authors: Long, J.-D., Liu Y., Jiao D.-L., Wang Y.-J., Zan G.-Y., Ju Y.-Y., Zhao M., Liu J.-G. NMDA antagonist memantine on methamphetamine exposure-induced cortical Bcl-2/caspase-3 protein expression and object recognition memory impairment in mice
Long, J.-D., Liu Y., Jiao D.-L., Wang Y.-J., Zan G.-Y., Ju Y.-Y., Zhao M., Liu J.-G. - 2017
The ameliorating effect of 1-palmitoyl-2-linoleoyl-3-acetylglycerol on scopolamine-induced memory impairment vua acetylcholinesterase inhibition and LTP activation
Authors: Jeon, S.J., Kim B., Park H.J., Zhang J., Kwon Y., Kim D.H., Ryu J.H. 1-palmitoyl-2-linoleoyl-3-acetylglycerol (PLAG) and donezepil on scopolamine-induced brain acetylcholinesterase levels, hippocampal neuron excitability, CREB, extracellular signal-regulated kinase, calcium calmodulin kinase II levels, locomotion, exploration, passive avoidance and spatial learning impairment in mice
Jeon, S.J., Kim B., Park H.J., Zhang J., Kwon Y., Kim D.H., Ryu J.H. - 2017
Geniposide ameliorates cognitive deficits by attenuating the cholinergic defect and amyloidosis in middle-aged Alzheimer model
Authors: Zhao, C., Zhang H., Li H., Lv H., Liu X., Li Z., Xin W., Wang Y., Zhang W. Glycoside geniposide oh hippocampal cholinergic function/neuroprotection, hippocampal/cortical amyloid βaccumulation and Morris water maze performance in APP/PS1 middle-aged Alzheimer's model mice
Zhao, C., Zhang H., Li H., Lv H., Liu X., Li Z., Xin W., Wang Y., Zhang W. - 2017
Long-term cilostazol administration ameliorates memory decline in senescence-accelerated mouse prone 8 (SAMP8) through a dual effect on cAMP and blood-brain barrier
Authors: Yanai, S., Toyohara J., Ishiwata K., Ito H., Endo S. Phosphodiesterase inhibitor cilostazol on hippocampal, amygdalar CREB phosphorylation, pain sensitivity and fear conditioning in SAMP1 and SAMP8 (senescence-accelerated model) middle-age mice
Yanai, S., Toyohara J., Ishiwata K., Ito H., Endo S. - 2017
FFPM, a PDE4 inhibitor, reverses learning and memory deficits in APP/PS1 transgenic mice via cAMP/PKA/CREB signaling and anti-inflammatory effects
Authors: Guo, H., Cheng Y., Wang C., Wu J., Zou Z., Niu B., Yu H., Wang H., Xu J. Phosphodiesterase 4 inhibitor on hippocampal brain-derived neurotrophic factor, protein kinase A, cAMP, CREB and cytokines expression, passive avoidance and Morris water maze performance in APP/PS1 Alzheimer's disease model mice
Guo, H., Cheng Y., Wang C., Wu J., Zou Z., Niu B., Yu H., Wang H., Xu J. - 2017
Tongxinluo improves cognition by decreasing β-amyloid in spontaneous hypertensive rats
Authors: Fei, Y.-L., Lv H.-J., Li Y.-B., Liu J., Qian W.-N., Ma K.-G., Li H.-b., Qu Q.-M. Tongxinluo on hippocampal amyloid βlevels and Morris water maze performance in spontaneously hypertensive rats: β-secretase role
Fei, Y.-L., Lv H.-J., Li Y.-B., Liu J., Qian W.-N., Ma K.-G., Li H.-b., Qu Q.-M. - 2017
Tropisetron sensitizes α7 containing nicotinic receptors to low levels of acetylcholine in vitro and improves memory-related task performance in young and aged animals
Authors: Callahan, P.M., Bertrand D., Bertrand S., Plagenhoef M.R., Terry A.V. Jr. 5-HT3 antagonist, α7-32nAchR agonist tropisetron on oocyte excitability, object recognition in rats of different age/strain and operant responding in male and female aged monkeys
Callahan, P.M., Bertrand D., Bertrand S., Plagenhoef M.R., Terry A.V. Jr. - 2017
Overexpression of phosphodiesterase-4 subtypes involved in surgery-induced neuroinflammation and cognitive dysfunction in mice
Authors: Wang, W., Zhang X., Feng Z., Wang D., Zhang H., Sui B., Zhang Y., Zhao W., Fu Q., Xu Z., Mi W. Phosphodiesterase-4 inhibitor rolipram on surgery effects on hippocampal cytokines/CREB levels, locomotion/exploration, fear conditioning and Morris water maze performance in mice
Wang, W., Zhang X., Feng Z., Wang D., Zhang H., Sui B., Zhang Y., Zhao W., Fu Q., Xu Z., Mi W. - 2017
Inhibitory effect of punicalagin on lipopolysaccharide-induced neuroinflammation, oxidative stress and memory impairment via inhibition of nuclear factor-kappaB
Authors: Kim, Y.E., Hwang C.J., Lee H.P., Kim C.S., Son D.J., Ham Y.W., Hellstrom M., Han S.-B., Kim H.S., Park E.K., Hong J.T. Punicalagin on lipopolysaccharide-induced brain neuroinflammation/oxidative stress, Morris water maze and passive avoidance impairment in mice
Kim, Y.E., Hwang C.J., Lee H.P., Kim C.S., Son D.J., Ham Y.W., Hellstrom M., Han S.-B., Kim H.S., Park E.K., Hong J.T. - 2017
Short-term treatment with flumazenil restores long-term object memory in a mouse model of Down syndrome
Authors: Colas, D., Chuluun B., Garner C.C., Heller H.C. GABA-A antagonist flumazenil on object recognition performance in Trisomic 16 and control mice
Colas, D., Chuluun B., Garner C.C., Heller H.C. - 2017
Protective effect of dapsone on cognitive impairment induced by propofol involves hippocampal autophagy
Authors: Yang, N., Li L., Li Z., Ni C., Cao Y., Liu T., Tian M., Chui D., Guo X. Dapsone on propofol-induced hippocampal autophagy and Morris water maze impairment in old rats
Yang, N., Li L., Li Z., Ni C., Cao Y., Liu T., Tian M., Chui D., Guo X. - 2017
Effect of insulin on spatial memory in aluminum chloride-induced dementia in rats
Authors: Nampoothiri, M., Kumar N., Ramalingayya G.V., Kutty N.G., Krishnadas N., Rao C.M. Glucose rivastigmine and insulin on aluminum chloride-induced hippocampal and frontal oxidative stress, acetylcholine levels and spatial learning impairment in mice
Nampoothiri, M., Kumar N., Ramalingayya G.V., Kutty N.G., Krishnadas N., Rao C.M. - 2017
Short-term green tea supplementation prevents recognition memory deficits and ameliorates hippocampal oxidative stress induced by different stroke models in rats
Authors: Altermann, C.D.C., Souza M.A., Schimidt H.L., Izaguirry A.P., Martins A., Garcia A., Santos F.W., Mello-Carpes P.B. Green tea supplementation on transient ischemia or intracerebral hemorrhage-induced hippocampal oxidative stress, exploration, grooming and object recognition impairment in rats
Altermann, C.D.C., Souza M.A., Schimidt H.L., Izaguirry A.P., Martins A., Garcia A., Santos F.W., Mello-Carpes P.B. - 2017
Ellagic acid ameliorates learning and memory deficits in a rat model of Alzheimer's disease: an exploration of underlying mechanisms
Authors: Kiasalari, Z., Heydarifard R., Khalili M., Afshin-Majd S., Baluchnejadmojarad T., Zahedi E., Sanaierad A., Roghani M. Systemic ellagic acid on intra-hippocampal amyloid β25-35 effects on hippocampal neuron damage, acetylcholinesterase, oxidative stress levels, passive avoidance, object recognition and spatial learning deficit in rats
Kiasalari, Z., Heydarifard R., Khalili M., Afshin-Majd S., Baluchnejadmojarad T., Zahedi E., Sanaierad A., Roghani M. - 2017
The protective effect of astaxanthin on learning and memory deficits and oxidative stress in a mouse model of repeated cerebral ischemia/reperfusion
Authors: Xue, Y., Qu Z., Fu J., Zhen J., Wang W., Cai Y., Wang W. Carotenoid astaxanthin on cerebral ischemia effects on hippocampal neuron damage/oxidative stress and Morris water maze performance in mice
Xue, Y., Qu Z., Fu J., Zhen J., Wang W., Cai Y., Wang W. - 2017
(-)-Epigallocatechin-3-gallate ameliorates memory impairment and rescues the abnormal synaptic protein levels in the frontal cortex and hippocampus in a mouse model of Alzheimer's disease
Authors: Guo, Y., Zhao Y., Nan Y., Wang X., Chen Y., Wang S. Green tea polyphenolic (-)-epigallocatechin-3-gallate on hippocampal, frontal synaptic proteins/amyloidβ1-42 levels, locomotor activity and spatial learning in SAMP8 and control mice
Guo, Y., Zhao Y., Nan Y., Wang X., Chen Y., Wang S. - 2017
Co-modulation of an allosteric modulator of nicotinic receptor-cholinergic inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse
Authors: Freret, T., Lelong-Boulouard V., Lecouflet P., Hamidouche K., Dauphin F., Boulouard M. Galantamine and 5-HT4 agonist on passive avoidance and spatial memory in scopolamine-induced memory deficit and control mice
Freret, T., Lelong-Boulouard V., Lecouflet P., Hamidouche K., Dauphin F., Boulouard M. - 2017
MAM-E17 rat model impairments on a novel continuous performance task: effects of potential cognitive enhancing drugs
Authors: Mar, A.C., Nilsson S.R.O., Gamallo-Lana B., Lei M., Dourado T., Alsio J., Saksida L.M., Bussey T.J., Robbins T.W. Nootropics effects on "continuous operant" performance in adult rat offspring by dams methylazoxymethanol acetate/MAM exposed on gestational day 17
Mar, A.C., Nilsson S.R.O., Gamallo-Lana B., Lei M., Dourado T., Alsio J., Saksida L.M., Bussey T.J., Robbins T.W. - 2017
Neuroprotective effect of ipriflavone against scopolamine-induced memory impairment in rats
Authors: Hafez, H.S., Ghareeb D.A., Saleh S.R., Abady M.M., El Demellawy M.A., Hussien H., Abdel-Monem N. Ipriflavone and donepezil on scopolamine exposure effects on hippocampal acetylcholine, brain-derived neurotrophic factor, CREB, extracellular signal-regulated kinase, oxidative stress, neuronal damage levels and Morris water maze performance in rats
Hafez, H.S., Ghareeb D.A., Saleh S.R., Abady M.M., El Demellawy M.A., Hussien H., Abdel-Monem N. - 2017
Protective effects of kinetin against aluminum chloride and D-galactose induced cognitive impairment and oxidative damage in mouse
Authors: Wei, Y., Liu D., Zheng Y., Li H., Hao C., Ouyang W. Kinetin cytokinin on aluminum chloride and D-galactose effects on cortical, hippocampal acetylcholine, acetylcholinesterase, amytlogenic proteins, oxidative damage levels and Morris water maze performance in mice
Wei, Y., Liu D., Zheng Y., Li H., Hao C., Ouyang W. - 2017
A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat
Authors: Hussein, A.M., Aher Y.D., Kalaba P., Aher N.Y., Dragacevic V., Radoman B., Ilic M., Leban J., Beryozkina T., Ahmed A.B.M.A., Urban E., Langer T., Lubec G. CE125 dopamine re-uptake inhibitor on response to stress, locomotion, exploration and spatial learning in rats
Hussein, A.M., Aher Y.D., Kalaba P., Aher N.Y., Dragacevic V., Radoman B., Ilic M., Leban J., Beryozkina T., Ahmed A.B.M.A., Urban E., Langer T., Lubec G. - 2017
Supplementation with zinc in rats enhances memory and reverses an age-dependent increase in plasma copper
Authors: Sandusky-Beltran, L.A., Manchester B.L., McNay E.C. Zinc supplementation on hippocampal copper levels, exploratory activity, spatial learning and object recogntion in young and adult rats
Sandusky-Beltran, L.A., Manchester B.L., McNay E.C. - 2017
Piracetam attenuates LPS-induced neuroinflammation and cognitive impairment in rats
Authors: Tripathi, A., Paliwal P., Krishnamurthy S. Piracetam on lipopolysaccharide-induced effects on hippocampal and prefrontal neuroinflammation, locomotion/exploration and spatial learning in rats
Tripathi, A., Paliwal P., Krishnamurthy S. - 2017
Quercetin ameliorates chronic unpredicted stress-induced behavioral dysfunction in male Swiss albino mice by modulating hippocampal insulin signaling pathway
Authors: Mehta, V., Singh T.R., Udayabanu M. Quercitin on stress effects on hippocampal neurogenesis/insulin expression levels, locomotor activity, response to stress and passive avoidance performance in mice
Mehta, V., Singh T.R., Udayabanu M. - 2017
Behavioural pharamcology of the α5-GABAA receptor antagonist S44819: enhacement and remediation of cognitive performance in preclinical models
Authors: Gacsalyi, I., Moricz K., Gigler G., Wellmann J., Nagy K., Ling I., Barkoczy J., Haller J., Lambert J.J., Szenasi G., Spedding M., Antoni F.A. α5-GABA-A antagonist S44819 on social interaction, response to stress, object recognition, social avoidance, fear conditioning extinction, fear potentiated startle and spatial learning in mice: effects on ketamine and phencyclidine amnesic exposure
Gacsalyi, I., Moricz K., Gigler G., Wellmann J., Nagy K., Ling I., Barkoczy J., Haller J., Lambert J.J., Szenasi G., Spedding M., Antoni F.A. - 2017
Piracetam inhibits ethanol (EtOH)-induced memory deficit by mediating multiple pathways
Authors: Yang, Y., Feng J., Xu F., Wang J. Piracetam on ethanol-induced effects on hippocampal neuron excitability/plasticity damage and spatial learning deficit in rats
Yang, Y., Feng J., Xu F., Wang J. - 2017
Ferulic acid attenuates diabets-induced cognitive impairment in rats via regulation of PTP1B and insulin signaling pathway
Authors: Wang, H., Sun X., Zhang N., Ji Z., Ma Z., Fu Q., Qu R., Ma S. Fenolic ferulic acid on streptozotocin-induced effects on hippocampal cell neuroinflammation, neurodegeneration and apoptosis and Morris water maze performance in rats
Wang, H., Sun X., Zhang N., Ji Z., Ma Z., Fu Q., Qu R., Ma S. - 2017
M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory
Authors: Volmar, C.-H., Salah-Uddin H., Janczura K.J., Halley P., Lambert G., Wodrich A., Manoah S., Patel N.H., Sartor G.C., Mehta N., Miles N.T.H., Desse S., Dorcius D., Cameron M.D., Brothers S.P., Wahlestedt C. Histone deacetylase inhibitor M344 on β-amyloid inducing neurodisregulation and object recognition/spatial learning impairment in mice
Volmar, C.-H., Salah-Uddin H., Janczura K.J., Halley P., Lambert G., Wodrich A., Manoah S., Patel N.H., Sartor G.C., Mehta N., Miles N.T.H., Desse S., Dorcius D., Cameron M.D., Brothers S.P., Wahlestedt C. - 2017