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2019
Ketamine: a paradigm shift for depression research and treatment
Authors: Krystal, J.H., Abdallah C.G., Sanacora G., Charney D.S., Duman R.S. Ketamine as antidepressant - Review
Krystal, J.H., Abdallah C.G., Sanacora G., Charney D.S., Duman R.S. - 2019
The gap junction inhibitor INI-0602 attenuates mechanical allodynia and depression-like behaviors induced by spared nerve injury in rats
Authors: Zhang, X.-M., Wang L.-Z., He B., Xiang Y.-K., Fan L.-X., Wang Q., Tao L. Gap junction inhibitor INI-0602 on neuropathic pain by nerve injury and related effects on spinal cord BDNF/Nr2b expression, sucrose preference and response to stress in rats
Zhang, X.-M., Wang L.-Z., He B., Xiang Y.-K., Fan L.-X., Wang Q., Tao L. - 2019
Loss of FKBP5 affects neuron synaptic plasticity: an electrophysiology insight
Authors: Qiu, B., Xu Y., Wang J., Liu M., Dou L., Deng R., Wang C., Williams K.E., Stewart R.B., Xie Z., Ren W., Zhao Z., Shou W., Liang T., Yong W. Glucocorticoid receptor role on hippocampal neuron excitability sweet/bitter taste preference and response to stress in mice
Qiu, B., Xu Y., Wang J., Liu M., Dou L., Deng R., Wang C., Williams K.E., Stewart R.B., Xie Z., Ren W., Zhao Z., Shou W., Liang T., Yong W. - 2019
MicroRNA-186-5p controls GluA2 surface expression and synaptic scaling in hippocampal neurons
Authors: Silva, M.M., Rodrigues B., Fernandes J., Santos S.D., Carreto L., Santos M.A.S., Pinheiro P., Carvalho A.L. GluA2 AMPA receptor role in hippocampal neuron excitability/plasticity in rats: microRNA-186-5p role
Silva, M.M., Rodrigues B., Fernandes J., Santos S.D., Carreto L., Santos M.A.S., Pinheiro P., Carvalho A.L. - 2019
Flumazenil but not bicuculline counteract the impairing effects of anesthetic ketamine on recongition memory in rats. Evience for a functional interaction between the GABAA-benzodiazepine receptor and ketamine?
Authors: Lafioniatis, A., Bermperian V.C., Pitsikas N. Benzodiazepine receptor antagonist flumazenil or gABA antagonist bicuculline exposure effects on object recognition impairment by pre-training and post-training ketamine induced anethesia in rats
Lafioniatis, A., Bermperian V.C., Pitsikas N. - 2019
Acute administration of ketamine attenuates the impairment of social behaviors induced by social defeat stress exposure as juveniles via activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors
Authors: Hasegawa, S., Yoshimi A., Mouri A., Uchida Y., Hida H., Mishina M., Yamada K., Ozaki N., Nabeshima T., Noda Y. AMPA and NMDA receptor modulation on social defeat exposure effects on social interaction and related hippocampal/prefrontal neuronal protein levels in juvenile rats
Hasegawa, S., Yoshimi A., Mouri A., Uchida Y., Hida H., Mishina M., Yamada K., Ozaki N., Nabeshima T., Noda Y. - 2019
Hypothalamic endocannabinoid signalling modulates aversive responses related to panic attacks
Authors: Viana, T.G., Bastos J.R., Costa R.B., Hott S.C., Mansur F.S., Coimbra C.C., Resstel L.B., Aguiar D.C., Moreira F.A. Dorsomedial hypothalamic NMDA and endocannabinoid signaling on panic-like locomotor behavior and vardiovascular response in rats
Viana, T.G., Bastos J.R., Costa R.B., Hott S.C., Mansur F.S., Coimbra C.C., Resstel L.B., Aguiar D.C., Moreira F.A. - 2019
Ketamine normalizes binge drinking-induced defects in glutamatergic synaptic transmission and ethanol drinking behavior in female but not male mice
Authors: Crowley, N.A., Magee S.N., Feng M., Jefferson S.J., Morris C.J., Dao N.C., Brockway D.F., Luscher B. Ketamine exposure on alcohol binge drinking behavior and related prefrontal neuronal glutamate receptor expression/excitability in male and female mice
Crowley, N.A., Magee S.N., Feng M., Jefferson S.J., Morris C.J., Dao N.C., Brockway D.F., Luscher B. - 2019
Early life stress impairs fear memory and synaptic plasticity; a potential role for GluN2B
Authors: Lesuis, S.L., Lucassen P.J., Krugers H.J. Early life stress on hippocampal neuron excitabiulity/NMDA receptor-synaptic proiteins expression, response to stress and fear conditioning in adult mice
Lesuis, S.L., Lucassen P.J., Krugers H.J. - 2019
Amantadine enhances nigrostriatal and mesolimbic dopamine function in the rat brain in relation to motor and exploratory activity
Authors: Nikolaus, S., Wittsack, H.-J., Beu M., Antke C., Hautzel H., Wickrath F., Muller-Lutz A., De Souza Silva M.A., Huston J.P., Antoch G., Muller H.-W. NMDA antagonist amantadine exposure on brain D2/D3 binbding and locomotion/exploration/rearing/grooming in rats
Nikolaus, S., Wittsack, H.-J., Beu M., Antke C., Hautzel H., Wickrath F., Muller-Lutz A., De Souza Silva M.A., Huston J.P., Antoch G., Muller H.-W. - 2019
Interemisperic plasticity is mediated by maximal potentiation of callosal inputs
Authors: Petrus, E., Saar G., Ma Z., Dodd S., Isaac J.T.R., Koretsky A.P. Callosal NMDA/AMPA receptor mediated excitability and cortical interhemispheric connectivity in mice
Petrus, E., Saar G., Ma Z., Dodd S., Isaac J.T.R., Koretsky A.P. - 2019
Cholecystokinin release triggered by NMDA receptors produces LTP and sound-sound associative memory
Authors: Chen, X., Li X., Wong Y.T., Zheng X., Wang H., Peng Y., Feng H., Feng J., Baibado J.T., Jesky R., Wang Z., Xie H., Sun W., Zhang Z., Zhang X., He L., Zhang N., Zhang Z., Tang P., Su J., Hu L.-L., Liu Q., He X., Tan A., Sun X., Li M., Wong K., Wang X., Cheung H.-Y., Shum D.K.-Y., Yung K.K.L., Chan Y.-S., Tortorella M., Guo Y., Xu F., He J. CCK/NMDA signaling role in entorhinal-neocortical projection excitability and cue-cue associative learning in rats and mice
Chen, X., Li X., Wong Y.T., Zheng X., Wang H., Peng Y., Feng H., Feng J., Baibado J.T., Jesky R., Wang Z., Xie H., Sun W., Zhang Z., Zhang X., He L., Zhang N., Zhang Z., Tang P., Su J., Hu L.-L., Liu Q., He X., Tan A., Sun X., Li M., Wong K., Wang X., Cheung H.-Y., Shum D.K.-Y., Yung K.K.L., Chan Y.-S., Tortorella M., Guo Y., Xu F., He J. - 2019
A silent eligibility trace enables dopamine-dependent synaptic plasticity for reinforcement learning in the mouse striatum
Authors: Shindou, T., Shindou M., Watanabe S., Wickens J. Dopaminergic striatal neuron excitability modulation in mice
Shindou, T., Shindou M., Watanabe S., Wickens J. - 2019
Cyclohexane inhialation produces long-lasting alterations in the hippocampal integrity and reward-seeking behavior in the adult mouse
Authors: Campos-Ordonez, T., Zarate-Lopez D., Ibarra-Castaneda N., Buritica J., Gonzalez-Perez O. Cyclohexane exposure on hippocampal neuronal c-fos/NMDA receptor expression, apoptotic cell numebr and motor/operant learning performance in mice
Campos-Ordonez, T., Zarate-Lopez D., Ibarra-Castaneda N., Buritica J., Gonzalez-Perez O. - 2019
Sigma-1 receptor antagonist PD144418 suppresses food reinforced operant responding in rats
Authors: Tapia, M.A., Lee J.R., Gereau G.B., Moore J.M., Weise V.N., Mason K.L., Cessac M.E., Bodeen J.L., Miller D.K., Will M.J. Sigma-1 receptor antagonist PD144418 on appetitively rewarded operant responding in rats
Tapia, M.A., Lee J.R., Gereau G.B., Moore J.M., Weise V.N., Mason K.L., Cessac M.E., Bodeen J.L., Miller D.K., Will M.J. - 2019
Periconceptional maternal alcohol consumption leads to behavioural changes in adult and aged offspring and alters the expression of hippocampal genes associated with learning and memory and regulators of the epigenome
Authors: Lucia, D., Burgess D., Cullen C.L:, Dorey E.S., Rawashdeh O., Moritz K.M. Periconceptual maternal alcohol consumption on hippocampal NMDA receptor/BDNF/epigentic modifiers expression, exploratory activity, object recognition and spatial learning in male and female adult and aged reat offspring
Lucia, D., Burgess D., Cullen C.L:, Dorey E.S., Rawashdeh O., Moritz K.M. - 2019
The effects of early exposure to MK-801 during environmental enrichment on spatial memory, methamphetamine self-administration and cue-iduced renewal in rats
Authors: Zhang, P., Pan J., Mao Z., Xu X., Lin D., Wu B., Zhou W., Liu Y. Environmental enrichment rearing and MK-801 exposure effects on Morris water maze, methamphetamine operant self-admiistration and related brain NMDA receptor/c-fos expression in rats
Zhang, P., Pan J., Mao Z., Xu X., Lin D., Wu B., Zhou W., Liu Y. - 2019
Ablation of NMDA receptors in dopamine neurons disrupt attribution of incentive salience to reward-paired stimuli
Authors: Cieslak, P.E., Parkitna J.R. Dopaminergic neuron NMDA receptor role in Pavlovian/operant appetitive rewarded performing in mice
Cieslak, P.E., Parkitna J.R. - 2019
Molecular mechanisms underlying striatal synaptic plasticity: relevance to chronic alcohol consumption and seeking
Authors: Blackwell, K.T., Salinas A.G., Tewatia P., English B., Kotaleski J.H., Lovinger D.M. Striatal synaptic plasticity/excitability molecular mechanism computational model related to alcohol exposure
Blackwell, K.T., Salinas A.G., Tewatia P., English B., Kotaleski J.H., Lovinger D.M. - 2019
Altered connectivity in depression: GABA and glutamate neurotransmitter deficits and reversal by novel treatments
Authors: Duman, R.S., Sanacora G., Krystal J.H. Glutamate and GABA signaling in depression and stress related disorders - Review
Duman, R.S., Sanacora G., Krystal J.H. - 2019
The role of depressive subtypes within the neuroinflammation hypothesis of major depressive disorder
Authors: Woelfer, M., Kasties V., Kahlfuss S., Walter M. Neuroinflammation and depressive disorders - Review
Woelfer, M., Kasties V., Kahlfuss S., Walter M. - 2019
Acute ketamine administration attenuates lipopolysaccharide-induced depressive-like behavior by reversing abnormal regional homogeneity in the nucleus accumbens
Authors: Ji, M., Mao M., Li S., Zhang L., Qiu L., Li B., Xia J., Yang J. Ketamine exposure on lipopolysaccharide-induced changes in plasma pro-inflammatory mediators levels, caudatal/accumbal activity, locomotion/exploration and response to stress in rats
Ji, M., Mao M., Li S., Zhang L., Qiu L., Li B., Xia J., Yang J. - 2019
Impaired cognitive flexibility following NMDAR-GluN2B deletion is associated with altered orbitofrontal-striatal function
Authors: Marquardt, K., Josey M., Kenton J.A., Cavanagh J.F., Holmes A., Brigman J.L. Prefrontal and hippocampal GluN2B receptor role in prefrontal cortex/striatal neuron excitability and operant responding in mice
Marquardt, K., Josey M., Kenton J.A., Cavanagh J.F., Holmes A., Brigman J.L. - 2019
Progressive alterations in synaptic transmission and plasticity of area CA1 precede the cognitive impairment associated with neontal administration of MK-801
Authors: Hernandez-Frausto, M., Lopez-Rubalcava C., Galvan E.J. Neonatal MK-801 exposure on hippocampal neuronal developmental plasticity/excitability, prepulese inhibition of the startle reflex, social interaction and object recognition in adolescent and adult rats
Hernandez-Frausto, M., Lopez-Rubalcava C., Galvan E.J. - 2019
NMDA receptor deletion on dopamine neurons disrupts visual discrimination and reversal learning
Authors: Radke, A.K., Zweifel L.S., Holmes A. Dopaminergic neuron NR1 receptor role on operant/visual discrimination-based responding in mice
Radke, A.K., Zweifel L.S., Holmes A. - 2019
Effects of tipepidine on MK-801-induced cognitive impairment in mice
Authors: Miki, R., Honda I., Hamasaki R., Kawahara R., Soeda F., Shirasaki T., Misumi S., Takahama K. Antitussive tipepidine on ventral tegmental area neuron GIRK-channel dependent excitability, MK-801 effects on object recognition and spatial learning in mice
Miki, R., Honda I., Hamasaki R., Kawahara R., Soeda F., Shirasaki T., Misumi S., Takahama K. - 2019
Early enriched environment prevents cognitive impairment in an animal model of schizophrenia induced by MK-801: role of hippocampal BDNF
Authors: Faatehi, M., Basiri M., Nezhadi A., Shabani M., Masoumi-Ardakani Y., Soltani Z., Nozari M. Environmental enrichment rearing on early life MK-801 exposure effects on hippocampal BDNF levels and object recognition performance in male and female adult rats
Faatehi, M., Basiri M., Nezhadi A., Shabani M., Masoumi-Ardakani Y., Soltani Z., Nozari M. - 2019
Layer-specific involvement of endocannabinoid signaling in muscarinic-induced long-term depression in layer 2/3 pyramidal neurons of rat visual cortex
Authors: Joo, K., Cho K.-H., Youn S.-H., Jang H.-J., Rhie D.-J. Endocannabinoid modulation on visual cortex neuron muscarinic induced NMDA-dependent LTD in rats
Joo, K., Cho K.-H., Youn S.-H., Jang H.-J., Rhie D.-J. - 2019
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation
Authors: Moda-Sava, R.N., Murdock M.H., Parekh P.K., Fetcho R.N., Huang B.S., Huynh T.N., Witztum J., Shaver D.C., Rosenthal D.L:, Alway E.J., Lopez K., Meng Y., Nellissen L., Grosenick L., Milner T.A., Deisseroth K., Bito H., Kasai H., Liston C. Corticosterone as depressive/anxiogenic and ketamine as antidepressant effects on prefrontal cortex neuron plasticity, sucrose preference, exploratory behavior and response to stress in mice
Moda-Sava, R.N., Murdock M.H., Parekh P.K., Fetcho R.N., Huang B.S., Huynh T.N., Witztum J., Shaver D.C., Rosenthal D.L:, Alway E.J., Lopez K., Meng Y., Nellissen L., Grosenick L., Milner T.A., Deisseroth K., Bito H., Kasai H., Liston C. - 2019
Ketamine improved depressive-like behaviors via hippocampal glucocorticoid receptor in chronic stress induced-susceptible mice
Authors: Wang, W., Liu L., Yang X., Gao H., Tang Q.-K., Yin L.-Y., Yin X.-Y., Hao J.-R., Geng D.-Q., Gao C. Ketamine and nifepristone exposure on social defeat stress effects on hippocampal/prefrontal glucocorticoid receptor expression, plasma corticosterone levels, sucrose preference, locomotion/exploration, response to stress and social interaction in mice: resilience/susceptibility study
Wang, W., Liu L., Yang X., Gao H., Tang Q.-K., Yin L.-Y., Yin X.-Y., Hao J.-R., Geng D.-Q., Gao C. - 2019