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2015
Effects of methylphenidate on the behavior of male 5xFAD mice
Authors: Schneider, F., Baldauf K., Wetzel W., Reymann K.G. Methylphenidate on locomotion/exploration and Morris water maze performance in 5xFAD and control 6- and 9-month-old mice
Schneider, F., Baldauf K., Wetzel W., Reymann K.G. - 2015
Increased ultrasonic vocalizations and risk-taking in rat pups of sleep-deprived dams
Authors: Gulia, K.K., Patel N., Kumar V.M. Exploratory activity and vocalization in rat pups from sleep-deprived dams
Gulia, K.K., Patel N., Kumar V.M. - 2015
Age-dependent effects of environmental enrichment on spatial memory and neurochemistry
Authors: Mora-Gallegos, A., Rojas-Carvajal M., Salas S., Saborio-Arce A., Fornaguera-Trias J., Brenes J.C. Rearing/exploration, spatial learning, hippocampal GABA/glutamate and ventral striatal dopamine in young and middle age rats
Mora-Gallegos, A., Rojas-Carvajal M., Salas S., Saborio-Arce A., Fornaguera-Trias J., Brenes J.C. - 2015
Postoperative cognitive dysfunction and microglial activation in associated brain regions in old rats
Authors: Hovens, I.B., van Leeuwen B.L., Nyakas C., Heineman E., van der Zee E.A., Schoemaker R.G. Post-operative impaired cognition, spontaneous behaviors and brain microglial activation by abdominal surgery in old rats
Hovens, I.B., van Leeuwen B.L., Nyakas C., Heineman E., van der Zee E.A., Schoemaker R.G. - 2015
Balance deficit enhances anxiety and balance training decreases anxiety in vestibular mutant mice
Authors: Shefer, S., Gordon C., Avraham K.B., Mintz M. Vestibular role in locomotion/exploration in mice of different age
Shefer, S., Gordon C., Avraham K.B., Mintz M. - 2015
The effects of Ginkgo biloba extract on cognitive functions in aged female rats: the role of oxidative stress and brain-derived neurotrophic factor
Authors: Belviranli, M., Okudan N. Ginkgo biloba extract on exploratory activity and Morris water maze perfomance in female rats of different age
Belviranli, M., Okudan N. - 2015
The different effects of maternal separation on spatial learning and reversal learning in rats
Authors: Wang, Q., Li M., Du W., Shao F., Wang W. Maternal separation on exploratory activity and spatial learning in rats of different age
Wang, Q., Li M., Du W., Shao F., Wang W. - 2015
Neuronal analysis and behaviour in prenatally gamma-irradiated rats
Authors: Kokosova, N., Tomasova L., Kiskova T., Smajda B. Prenatal gamma irradiation on adult hippocampal neurogenesis, exploration/grooming and Morris water maze performance in 2 and 3 months aged rats
Kokosova, N., Tomasova L., Kiskova T., Smajda B. - 2015
Flavonoid Chrysin prevents age-related cognitive decline via attenuation of oxidative stress and modulation of BDNF levels in aged mouse brain
Authors: Souza, L.C., Antunes M.S., Filho C.B., Del Fabbro L., de Gomes M.G., Rossito Goes A.T., Donato F., Prigol M., Boeira S.P., Jesse C.R. Flavonoid Chrysin on oxidative stress, brain derived neurotrophic factor levels, exploratory activity and Morris water maze performance in adult and aged mice
Souza, L.C., Antunes M.S., Filho C.B., Del Fabbro L., de Gomes M.G., Rossito Goes A.T., Donato F., Prigol M., Boeira S.P., Jesse C.R. - 2015
Neurobehavioural effects of exposure to fluoride in the earliest stages of rat development
Authors: Bartos, M., Gumilar F., Bras C., Gallegos C.E., Giannuzzi L., Cancela L.M., Minetti A. Prenatal/postnatal fluoride exposure on exploratory activity and grooming in 45 and 90 day old male and female rat offspring
Bartos, M., Gumilar F., Bras C., Gallegos C.E., Giannuzzi L., Cancela L.M., Minetti A. - 2015
Mice age - Does the age of the mother predict offspring behaviour?
Authors: Lerch, S., Brandwein C., Dormann C., Gass P., Chourbaji S. Mother age on offspring conditioned and unconditioned behaviors in mice
Lerch, S., Brandwein C., Dormann C., Gass P., Chourbaji S. - 2015
Acute social defeat stress increases the conditioned rewarding effects of cocaine in adult but not in adolescent mice
Authors: Montagud-Romero, S., Aguilar M.A., Maldonado C., Manzanedo C., Minarro J., Rodriguez-Arias M. Social defeat stress on conditioned place preference, exploratory activity and blood corticosterone levels in adolescent and adult mice
Montagud-Romero, S., Aguilar M.A., Maldonado C., Manzanedo C., Minarro J., Rodriguez-Arias M. - 2015
Reversal of age-associated cognitive deficits is accompanied by increased plasticity-related gene expression after chronic antidepressant administration in middle-aged mice
Authors: Li, Y., Abdourahman A., Tamm J.A., Pehrson A.L., Sanchez C., Gulinello M. Vartioxetine and fluoxetine on hippocampal plasticity, response to stress, exploratory activity, novel object place/recognition, social preference in mice of different age
Li, Y., Abdourahman A., Tamm J.A., Pehrson A.L., Sanchez C., Gulinello M. - 2015
Cognitive impairment and morphological changes in the dorsal hippocampus of very old female rats
Authors: Morel, G.R., Andersen T., Pardo J., Zuccolilli G.O., Cambiaggi V.L., Herenu C.B., Goya R.G. Hippocampal neuron degeneration, exploratory activity and spatial learning in female rats of different age
Morel, G.R., Andersen T., Pardo J., Zuccolilli G.O., Cambiaggi V.L., Herenu C.B., Goya R.G. - 2015
Chronic maternal hyperglycemia induced during mid-pregnancy in rats increases rage expression, augments hippocampal excitability, and alters behavior of the offspring
Authors: Chandna, A.R., Kuhlmann N., Bryce C.A., Greba Q., Campanucci V.A., Howland J.G. Chronic maternal hyperglicemia on RAGE protein expression, hippocampal neuron excitability, exploratory activity, prepulse inhibition of startle reflex, operant conditioning and object recognition in rat offspring
Chandna, A.R., Kuhlmann N., Bryce C.A., Greba Q., Campanucci V.A., Howland J.G. - 2015
Use of a force-sensing automated open field apparatus in a longitudinal study of multiple behavioral deficits in CAG140 Huntington's disease model mice
Authors: Fowler, S.C., Muma N.A. Locomotion/exploration and rearing in "CAG140" mutated mice of different age
Fowler, S.C., Muma N.A. - 2015
Combined administration of levetiracetam and valproic acid attenuates age-related hyperactivity of CA3 place cells, reduces place field area, and increases spatial information content in aged rat hippocampus
Authors: Robitsek, J., Ratner M.H., Stewart T., Eichenbaum H., Farb D.H. Levetiracetam and valpoic acid on exploration-dependent hippocampal place cell firing in rats of different age
Robitsek, J., Ratner M.H., Stewart T., Eichenbaum H., Farb D.H. - 2015
Loss of MeCP2 in parvalbumin- and somatostatin-expressing neurons in mice leads to distinct Rett syndrome-like phenotypes
Authors: Ito-Ishida, A., Ure K., Chen H., Swann J.W., Zoghbi H.Y. MeCP2 gene on hippocampal/cortical/striatal parvalbumin/somatostatin expressing neurons, social interaction, fear conditioning, startle reflex and motor coordination in mice of different age
Ito-Ishida, A., Ure K., Chen H., Swann J.W., Zoghbi H.Y. - 2015
Interaction of ApoE3 and ApoE4 isoforms with an ITM2b/BRI2 mutation linked to the Alzheimer disease-like Danish dementia: effects on learning and memory
Authors: Biundo, F., Ishiwari K., Del Prete D., D'Adamio L. ApoE3/4 glycoprotein on exploratory activity, object recognition and spatial learning in mice of different age
Biundo, F., Ishiwari K., Del Prete D., D'Adamio L. - 2015
Lower foraging efficiency in immatures drives spatial segregation with breeding adults in a long-lived pelagic seabird
Authors: Fayet, A.L., Freeman R., Shoji A., Padget O., Perrins C.M., Guilford T. Foraging in immature and adult Manx shearwater seabirds
Fayet, A.L., Freeman R., Shoji A., Padget O., Perrins C.M., Guilford T. - 2015
Time-place learning over a lifetime: absence of memory loss in trained old mice
Authors: Mulder, C.K., Reckman G.A.R., Gerkema M.P., Van der Zee E.A. Exploratory behavior, circadian activity and spatial learning in mice of different age
Mulder, C.K., Reckman G.A.R., Gerkema M.P., Van der Zee E.A. - 2015
Sleep deprivation during late pregnancy produces hyperactivity and increased risk-taking behavior in offspring
Authors: Radhakrishnan, A., Aswathy B.S., Kumar V.M., Gulia K.K. Late pregnancy sleep deprivation on locomotion/exploration/grooming in rat offspring
Radhakrishnan, A., Aswathy B.S., Kumar V.M., Gulia K.K. - 2015
Treadmill exercise enhances synaptic plasticity, but does not alter β-amyloid deposition in hippocampi of aged APP/PS1 transgenic mice
Authors: Zhao, G., Liu H.L., Zhang H., Tong X.J. Treadmill exercise on Morris water maze performance and hippocampal neuron excitability/β-amyloid level in APP/PS1 mice of different age
Zhao, G., Liu H.L., Zhang H., Tong X.J. - 2015
Adolescent rats are resistant to the development of ethanol-induced chronic tolerance and ethanol-induced conditioned aversion
Authors: Pautassi, R.M., Godoy J.C., Molina J.C. Ethanol on locomotor activity, body hypothermia and conditioned taste aversion induction in adolescent and adult rats
Pautassi, R.M., Godoy J.C., Molina J.C. - 2015
Spinocerebellar ataxia type 6 protein aggregates cause deificts in motor learning and cerebellar plasticity
Authors: Mark, M.D., Krause M., Boele H.-J., Kruse W., Pollok S., Kuner T., Dalkara D., Koekkoek S., De Zeeuw C.I., Herlitze S. Spinocerebellar ataxia typ6 protein on cerebellar neuron damage and excitability, locomotor coordination and eyeblink conditioning in mice
Mark, M.D., Krause M., Boele H.-J., Kruse W., Pollok S., Kuner T., Dalkara D., Koekkoek S., De Zeeuw C.I., Herlitze S. - 2015
Age moderates the effect of acute dopamine depletion on passive avoidance learning
Authors: Kelm, M.K., Boettiger C.A.Enhancement of memory consolidation by the histone deacetylase inhibitor sodium butyrate in aged rats
Authors: Blank, M., Werenicz A., Velho L.A., Pinto D.F., Fedi A.C., Lopes M.W., Peres T.V., Leal R.B., Dornelles A.S., Roesler R. Histone deacetylase inhibitor on passive avoidance consolidation in rats of different age
Blank, M., Werenicz A., Velho L.A., Pinto D.F., Fedi A.C., Lopes M.W., Peres T.V., Leal R.B., Dornelles A.S., Roesler R. - 2015
Cognitive impairments and neuronal injury in different brain regions of a genetic rat model of absence epilepsy
Authors: Jafarian, M., Karimzadeh F., Alipour F., Attari F., Lotfinia A.A., Speckmann E.-J., Zarrindast M.-R., Gorji A. Passive avoidance and hippocampal, cortical caspase-3 expression, apoptotic neurons in WAR/RiJ and Wistar rats of 2- and 6-months-old
Jafarian, M., Karimzadeh F., Alipour F., Attari F., Lotfinia A.A., Speckmann E.-J., Zarrindast M.-R., Gorji A. - 2015
Sex-dependent modulation of age-related cognitive decline by the L-type calcium channel gene Cacna1c (Cav 1.2)
Authors: Zanos, P., Bhat S., Terrillion C.E., Smith R.J., Tonelli L.H., Gould T.D. L-type calcium channel Cacna1c gene on passive avoidance, spatial learning and object recognition in male and female young and old mice
Zanos, P., Bhat S., Terrillion C.E., Smith R.J., Tonelli L.H., Gould T.D. - 2015
COBRA: a prospective multimodal imaging study of dopamine, brain structure and function, and cognition
Authors: Nevalainen, N., Riklund K., Andersson M., Axelsson J., Ogren M., Lovden M., Lindenberger U., Backman L., Nyberg L. "COBRA" study on brain function decline with age in humans - Review
Nevalainen, N., Riklund K., Andersson M., Axelsson J., Ogren M., Lovden M., Lindenberger U., Backman L., Nyberg L. - 2015