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2018
No effect of sex and estrous cycle on the fear potentiated startle response in rats
Authors: Zhao, Y., Bijlsma E.Y., Verdouw M.P., Groenink L. Benzadiazepine exposure effects on fear potentiated startle response in male and female rats
Zhao, Y., Bijlsma E.Y., Verdouw M.P., Groenink L. - 2018
Animals, anxiety, and anxiety disorders: how to measure anxiety in rodents and why
Authors: Harro, J. Anxiety rodent models - Review
Harro, J. - 2018
Embryonic alcohol exposure leading to social avoidance and latered anxiety responses in adult zebrafisk
Authors: Baggio, S., Mussulini B.H., de Oliveira D.L., Gerlai R., Rico E.P. Embryonic ethano exposure on social interaction and exploratory activity in adult zebrafishes
Baggio, S., Mussulini B.H., de Oliveira D.L., Gerlai R., Rico E.P. - 2018
The contribution of contextual fear in the anxiolytic effect of chlordiazepoxide in the fear-potentiated startle test
Authors: Zhao, Y., Bijlsma E.Y., Verdouw P.M., Garssen J., Groenink L. Contextual fear and benzodiazepine exposure on fear potentiated startle in rats
Zhao, Y., Bijlsma E.Y., Verdouw P.M., Garssen J., Groenink L. - 2018
Chronic minocycline treatment reduces the anxiety-like behaviors induced by repeated restraint stress through modulating neuroinflammation
Authors: Liu, H.-Y., Yue J., Hu L.-N., Cheng L.-F., Wang X.-S., Wang X.-J., Feng B. Minocycline exposure on stress effects on amygdalar neuronal oxidative stress and exploratory activity in mice
Liu, H.-Y., Yue J., Hu L.-N., Cheng L.-F., Wang X.-S., Wang X.-J., Feng B. - 2018
2017
Ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in BALB/cJ mice
Authors: Pham, T.H., Mendez-David I., Defaix C., Guiard B.P., Tritschler L., David D.J., Gardier A.M. Systemic or intra-medial prefrontal cortex ketamine and fluoxetine on medial prefrontal cortex serotonin level, dorsal raphe nuclei neuron firing, serotonin levels, exploratory activity, neophobia and response to stress in BALB/Cj anxious mice: dorsal raphe nuclei AMPA receptor role
Pham, T.H., Mendez-David I., Defaix C., Guiard B.P., Tritschler L., David D.J., Gardier A.M. - 2017
Anxiolytic effects of muscarinic acetylcholine receptors agonist oxotremorine in chronically stressed rats and related changes in BDNF and FGF2 levels in the hippocampus and prefrontal cortex
Authors: Di Liberto, V., Frinchi M., Verdi V., Vitale A., Plescia F., Cannizzaro C., Massenti M.F., Belluardo N., Mudò G. Oxotremorine on stress effects on plasma corticosterone level, hippocampal, prefrontal brain-derived neurotrophic factor, fibroblast growth factor-2 and extracellular signal-regulated kinase expression, neophobia, response to stress and exploratory activity in rats
Di Liberto, V., Frinchi M., Verdi V., Vitale A., Plescia F., Cannizzaro C., Massenti M.F., Belluardo N., Mudò G. - 2017
4'-Chlorodiazepam modulates the development of primary hippocampal neurons in a sex-dependent manner
Authors: Arbo, B.D., Vieira -Marques C., Ruiz-Palmero I., Ortiz-Rodriguez A., Arevalo M.A., Garcia-segura L.M., Ribeiro M.F. 4'-Chlorodiazepam on primary hippocampal neuron development of male and female mice
Arbo, B.D., Vieira -Marques C., Ruiz-Palmero I., Ortiz-Rodriguez A., Arevalo M.A., Garcia-segura L.M., Ribeiro M.F. - 2017
Decreased anxiety, voluntary ethanol intake and ethanol-induced CPP acquisition following activation of the metabotropic glutamate receptor 8 "mGluR8"
Authors: Bahi, A. mGluR8 agonist or antagonist on ethanol intake, exploratory activity, taste sensitivity and conditioned place preference by ethanol in mice
Bahi, A. - 2017
Opposing roles of primate areas 25 and 32 and their putative rodent homologs in the regulation of negative emotion
Authors: Wallis, C.U., Cardinal R.N., Alexander L., Roberts A.C., Clarke H.F. Ventromedial prefrontal cortex differential emotion regulation related to fear conditioning acquisition and extinction in primates
Wallis, C.U., Cardinal R.N., Alexander L., Roberts A.C., Clarke H.F. - 2017
The endocannabinoid system as a target for novel anxiolytic drugs
Authors: Patel, S., Hill M.N., Cheer J.F., Wotjak C.T., Holmes A. Cannabinoids, fear, stress and anxiety - Review
Patel, S., Hill M.N., Cheer J.F., Wotjak C.T., Holmes A. - 2017
The role of GABAA in the expression of updated information through the reconsolidation process in humans
Authors: Fernandez, R.S., Moyano M.D., Radloff M., Campos J., Carbò-Tano M., Allegri R.F., Pedreira M.E., Forcato C. Clomazepam on episodic memory reconsolidation in humans
Fernandez, R.S., Moyano M.D., Radloff M., Campos J., Carbò-Tano M., Allegri R.F., Pedreira M.E., Forcato C. - 2017
Further evaluation of the potential anxiolytic activity of imidazol[1,5α][1,4] diazepin agents selective for α2/3-containing GABAA receptors
Authors: Witkin, J.M., Cerne R., Wakulchik M., Gleason S.D., Jones T.M., Li G., Arnold L.A., Li J.-X., Schkeryantz J.M., Methuku K.R., Cook J.M., Poe M.M. Imidazol[1,5α][1,4] diazepin agent anxiolytic/anticonvulsant effects in rats
Witkin, J.M., Cerne R., Wakulchik M., Gleason S.D., Jones T.M., Li G., Arnold L.A., Li J.-X., Schkeryantz J.M., Methuku K.R., Cook J.M., Poe M.M. - 2017
Risk mitigation for children exposed to drugs during gestation: a critical role for animal preclinical behaioral testing
Authors: Zucker, I. Prenatal drug exposure animal models - Review
Zucker, I. - 2017
Abuse-related effects of subtype-selective GABAA receptor positive allosteric modulators in an assay of intracranial self-stimulation in rats
Authors: Schwienteck, K.L., Li G., Poe M.M., Cook J.M., Banks M.L., Negus S.S. GABA-A receptor agonist on operant hypothalamic medial forebrain bundle self-stimulation in rats
Schwienteck, K.L., Li G., Poe M.M., Cook J.M., Banks M.L., Negus S.S. - 2017
Short-term and long-term effects of diazepam on the memory for discrimination and generalization of scopolamine
Authors: Casasola-Castro, C., Weissmann-Sanchez L., Calixto-Gonzalez E., Aguayo-Del Castillo A., Velazquez-Martinez D.N. Diazepam on operant responding related to scopolamine drug state discrimination in rats
Casasola-Castro, C., Weissmann-Sanchez L., Calixto-Gonzalez E., Aguayo-Del Castillo A., Velazquez-Martinez D.N. - 2017
Amnestic drugs in the odor span task: effects of flunitrazepam, zolpidem and scopolamine
Authors: Galizio, M., Mathews M., Mason M., Panoz-Brown D., Prichard A., Soto P. GABA-A agonist and scopolamine on rewarded olfactory discrimination task performance in rats
Galizio, M., Mathews M., Mason M., Panoz-Brown D., Prichard A., Soto P. - 2017
Early deprivation increases high-leaning behavior, a novel anxiety-like behavior, in the open field test in rats
Authors: Kuniishi, H., Ichisaka S., Yamamoto M., Ikubo N., Matsuda S., Futora E., Harada R., Ishihara K., Hata Y. Early maternal separation diazepam administration and illumination intensity on exploratory/rearing activity in male and female adult rats
Kuniishi, H., Ichisaka S., Yamamoto M., Ikubo N., Matsuda S., Futora E., Harada R., Ishihara K., Hata Y. - 2017
Systemic administration of two different anxiolytic drugs decreases local field potential theta frequency in the medial entorhinal cortex without affecting grid cell firing fileds
Authors: Monaghan, C.K., Chapman IV G.W., Hasselmo M.E. 8-OH-DTAT and diazepam exposure on entorhinal grid cell firing and hippocampal theta rhythm in rats
Monaghan, C.K., Chapman IV G.W., Hasselmo M.E. - 2017
A comparison of behavioral and pharmacological interventions to attenuate reactivated fear memories
Authors: Monti, R.I.F., Alfei J.M., Mugnaini M., Bueno A.M., Beckers T., Urcelay G.P., Molina V.A. Post-reactivation extinction or midazolam exposure on fear conditioning retention in rats
Monti, R.I.F., Alfei J.M., Mugnaini M., Bueno A.M., Beckers T., Urcelay G.P., Molina V.A. - 2017
2016
AC-3933, a benzodiazepine partial inverse agonist, improves memory performance in MK-801-induced amnesia mouse model
Authors: Hashimoto, T., Iwamura Y. AC-3933 or FG-7142 benzodiazepine inverse agonist and donepezil effects on spatial learning deficit by MK-801 or scopolamine in mice
Hashimoto, T., Iwamura Y. - 2016
Animal models of bipolar mania: the past, present and future
Authors: Logan, R.W., McClung C.A. Bipolar disorder animal models - Review
Logan, R.W., McClung C.A. - 2016
Fluoxetine and diazepam acutely modulate stress induced-behavior
Authors: Giacomini, A.C.V.V., Abreu M.S., Giacomini L.V., Siebel A.M., Zimerman F.F., Rambo C.L:, Mocelin R., Bonan C.D., Piato A.L., Barcellos L.J.G. Diazepam, fluoxetine and stress effects on locomotion/exploration, social interaction and aggressive behavior in zebrafishes
Giacomini, A.C.V.V., Abreu M.S., Giacomini L.V., Siebel A.M., Zimerman F.F., Rambo C.L:, Mocelin R., Bonan C.D., Piato A.L., Barcellos L.J.G. - 2016
Diazepam effects on averisve memory retrieval and extinction: role of anxiety levels
Authors: Leao, A.H.F.F., Cabral A., Izidio G.S., Ribeiro A.M., Silva R.H. Diazepam effects on aversive memory extinction and retrieval in rats
Leao, A.H.F.F., Cabral A., Izidio G.S., Ribeiro A.M., Silva R.H. - 2016
Two short-acting kappa opioid receptor antagonists (zyklophin and LY2444296) exhibited different behavioral effects from the long-acting antagonist norbinaltorphimine in mouse anxiety tests
Authors: Huang, P., Yakovleva T., Aldrich J.V., Tunis J., Parry C., Liu-Chen L.-Y. κ-opioid antagonist on locomotion/exploration and neophobia in mice
Huang, P., Yakovleva T., Aldrich J.V., Tunis J., Parry C., Liu-Chen L.-Y. - 2016
A single dose of lorazepam reduces paired-pulse suppression of median nerve evoked somatosensory evoked potentials
Authors: Stude, P., Lenz M., Hoffken O., Tegenthoff M., Dinse H. Lorazepam on somatosensory paired-pulse evoked potentials suppression in humans
Stude, P., Lenz M., Hoffken O., Tegenthoff M., Dinse H. - 2016
Memory and hippocampal architecture following short-term midazolam in western diet-treated rats
Authors: Rosenberger, D.S., Falangola M.F., Ledreux A., Nie X., Suhre W.M., Boger H.A., Granholm A.-C. Midazolam on spatial learning and related hippocampal protein biochemistry in saturated fats diet exposed middle-aged rats
Rosenberger, D.S., Falangola M.F., Ledreux A., Nie X., Suhre W.M., Boger H.A., Granholm A.-C. - 2016
Beta arrestin 2 rather than G protein efficacy determines the anxiolytic-versus anridepressant-like effects of nociceptin/orphanin FQ receptor ligands
Authors: Asth, L., Ruzza C., Malfacini D., Medeiros I., Guerrini R., Zaveri N.T., Gavioli E.C., Calo' G. Nociceptin/orphanin neuropeptide on response to stress and exploratory activity in mice
Asth, L., Ruzza C., Malfacini D., Medeiros I., Guerrini R., Zaveri N.T., Gavioli E.C., Calo' G. - 2016
Behavioral and pharmacological validation of an integrated fear-potentiated startle and prepulse inhibition paradigm
Authors: Zhang, M., Li M. Integrated fear-potentiated startle and prepulse inhibition paradigm in rats: diazepam and phencyclidine effects - Methods
Zhang, M., Li M. - 2016
Towards optimized anesthesia protocols for streotactic surgery in rats: analgesic, stress and genela health effects of injectable anesthetics. A comparison of a recommended complete reversal anesthesia with traditional chloral hydrate monoanesthesia
Authors: Huske, C., Sander S.E., Hamann M., Kershaw O., Richter F., Richter A. General anesthesia protocols in rats - Methods
Huske, C., Sander S.E., Hamann M., Kershaw O., Richter F., Richter A. - 2016