Themes: NOOTROPICS

2008

Contained in: Neurosci. Biobehav. Rev., 2008: 32, 760-776

Botox for the brain: enhancement of cognition, mood and prosocial behaviour and blunting of unwanted memories

Authors: De Jongh, R., Bolt I., Schermer M., Olivier B.

  Cognitive enhancement - Review
  De Jongh, R., Bolt I., Schermer M., Olivier B. - 2008

  GLUTAMATE   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS   REVIEWS AND COMMENTARIES   PROTEINS AND GENES

2007

Contained in: Brain Res., 2007: 1129, 161-165

Ginkgo biloba extract improves spatial memory in rats mainly but not exclusively via a histaminergic mechanism

Authors: Yamamoto, Y., Adachi Y., Fujii Y., Kamei C.

  Ginkgo biloba on spatial memory deficit by H1 and acetylcholine antagonists in rats
  Yamamoto, Y., Adachi Y., Fujii Y., Kamei C. - 2007

  ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   HISTAMINE   NOOTROPICS
Contained in: Neuropharmacology, 2007: 52, 836-843

Ladostigil prevents gliosis, oxidative-nitrative stress and memory deficits induced by intracerebroventricular injection of streptozotocin in rats

Authors: Shoham, S., Bejar C., Kovalev E., Schirer-Apelbaum D., Weinstock M.

  Ladostigil on intracerebroventricular streptozotocin-induced oxidative stress and memory impairment in rats
  Shoham, S., Bejar C., Kovalev E., Schirer-Apelbaum D., Weinstock M. - 2007

  ACETYLCHOLINE   CENTRAL NERVOUS SYSTEM LESIONS   NOOTROPICS
Contained in: Neuropharmacology, 2007: 53, 563-573

VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux

Authors: Mohler, E.G., Shacham S., Noiman S., Lezoualc'h F., Robert S., Gastineau M., Rutkowski J., Marantz Y., Dumuis A., Bockaert J., Gold P.E., Ragozzino M.E.

  5-HT4 agonists on hippocampal acetylcholine and spatial learning in rats
  Mohler, E.G., Shacham S., Noiman S., Lezoualc'h F., Robert S., Gastineau M., Rutkowski J., Marantz Y., Dumuis A., Bockaert J., Gold P.E., Ragozzino M.E. - 2007

  ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   SEROTONIN
Contained in: Neuropharmacology, 2007: 53, 588-600

The effects of JWB1-84-1 on memory-related task performance by amyloid Aβ transgenic mice and by young and aged monkeys

Authors: Sood, A., Beach J.W., Webster S.J., Terry A.V. Jr., Buccafusco J.J.

  JWB1-84-1 on spontaneous and conditioned behavior in amyloid Abeta mice and in monkeys
  Sood, A., Beach J.W., Webster S.J., Terry A.V. Jr., Buccafusco J.J. - 2007

  ACETYLCHOLINE   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   OPERANT CONDITIONING   DARK/LIGHT CONTEXT   AGE   NOOTROPICS
Contained in: Behav. Pharmacol., 2007: 18, 347-363

Anti-dementia drugs and hippocampal-dependent memory in rodents

Authors: Yuede, C.M., Dong H., Csernansky J.G.

  Anti-dementia drugs and hippocampal-dependent memory in rodents - Review
  Yuede, C.M., Dong H., Csernansky J.G. - 2007

  ACETYLCHOLINE   CENTRAL NERVOUS SYSTEM LESIONS   HIPPOCAMPUS, FORNIX AND SUBICULUM   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS   NUCLEUS BASALIS MAGNOCELLULARIS   REVIEWS AND COMMENTARIES
Contained in: Neurobiol. Learn. Mem., 2007: 87, 218-224

Effect of chronic angiotensin converting enzyme inhibition on spatial memory and anxiety-like behaviors in rats

Authors: Jenkins, T.A., Chai S.Y.

  Angiotensin converting enzyme inhibitor on spatial memory in rats
  Jenkins, T.A., Chai S.Y. - 2007

  ANGIOTENSIN   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS
Contained in: Neurobiol. Learn. Mem., 2007: 87, 536-546

The ameliorating effect of oroxylin A on scopolamine-induced memory impairment in mice

Authors: Kim, D.H., Jeon S.J., Son K.H., Jung J.W., Lee S., Yoon B.H., Lee J.-J., Cho Y.-W., Cheong J.H., Ko K.H., Ryu J.H.

  Oroxylin A on memory deficits in mice
  Kim, D.H., Jeon S.J., Son K.H., Jung J.W., Lee S., Yoon B.H., Lee J.-J., Cho Y.-W., Cheong J.H., Ko K.H., Ryu J.H. - 2007

  ANXIOLYTIC DRUGS   AVOIDANCE   ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   γ-AMINO-BUTYRIC ACID (GABA)   NOOTROPICS
Contained in: Neurobiol. Learn. Mem., 2007: 87, 324-331

Reinstatement of episodic-like memory in rats by neurokinin-1 receptor antagonism

Authors: Kart-Teke, E., Dere E., Brandao M.L., Huston J.P. De Souza Silva M.A.

  Neurokinin-1 antagonist on locomotion, exploration and object recognition memory in rats
  Kart-Teke, E., Dere E., Brandao M.L., Huston J.P. De Souza Silva M.A. - 2007

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   NOOTROPICS
Contained in: J. Neurosci., 2007: 27, 5869-5878

Plant-derived flavanol (-)epicatechin enhances angiogenesis and retention of spatial memory in mice

Authors: Van Praag, H., Lucero M.J., Yeo G.W., Stecker K., Heivand N., Zhao C., Yip E., Afanador M., Schroeder H., Hammerstone J., Gage F.H.

  Epicatechin on spatial memory in sedentary or wheel running female mice
  Van Praag, H., Lucero M.J., Yeo G.W., Stecker K., Heivand N., Zhao C., Yip E., Afanador M., Schroeder H., Hammerstone J., Gage F.H. - 2007

  LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Brain Res., 2007: 1184, 254-259

SK-PC-B70M from Pulsatilla koreana improves scopolamine-­induced impairments of memory consolidation and spatial working memory

Authors: Han, C.-K., Park Y.H., Jin D.-Q., Hwang Y.K., Oh K.-B., Han J.-S.

  Pulsatilla koreana estract on scopolamine-induced Morris water amze and passive avoidance deficit in rats
  Han, C.-K., Park Y.H., Jin D.-Q., Hwang Y.K., Oh K.-B., Han J.-S. - 2007

  AVOIDANCE   ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS   CONSOLIDATION
Contained in: Behav. Brain Res., 2007: 183, 141-146

Effects of the active constituents of Crocus sativus L., crocins on recognition and spatial rats' memory

Authors: Pitsikas, N., Zisopoulou S., Tarantilis P.A., Kanakis C.D., Polissiou M.G., Sakellaridis N.

  Crocus sativus carotenoids on scopolamine-impaired recognition memory and spatial navigation in rats
  Pitsikas, N., Zisopoulou S., Tarantilis P.A., Kanakis C.D., Polissiou M.G., Sakellaridis N. - 2007

  ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2007: 86, 712-717

The brain metabolic enhancer methylene blue improves discrimination learning in rats

Authors: Wrubel, K.M., Riha P.D., Maldonado M.A., McCollum D., Gonzalez-Lima F.

  Methylene blue on spatial discrimination learning in rats
  Wrubel, K.M., Riha P.D., Maldonado M.A., McCollum D., Gonzalez-Lima F. - 2007

  SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2007: 88, 64-72

Catalpol ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by D-galactose

Authors: Zhang, X.L., Jiang B., Li Z.B., Hao S., An L.J.

  Catalpol on Morris water maze performance of D-galactose treated rats
  Zhang, X.L., Jiang B., Li Z.B., Hao S., An L.J. - 2007

  SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS
Contained in: Physiol. Behav., 2007: 92, 643-650

N-acetyl cysteine supplementation prevents impairment of spatial working memory functions in rats following exposure to hypobaric hypoxia

Authors: Jayalakshmi, K., Singh S.B., Kalpana B., Sairam M., Muthuraju S., Ilavazhagan G.

  N-acetyl cysteine on Morris water maze impairment induced by hypoxia in rats
  Jayalakshmi, K., Singh S.B., Kalpana B., Sairam M., Muthuraju S., Ilavazhagan G. - 2007

  SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS
Contained in: Faseb J., 2007: 21, 2400-2408

EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease

Authors: Tchantchou, F., Xu Y., Wu Y., Christen Y., Luo Y.

  Ginko biloba extract on hippocampal neurogenesis and CREB phosphorylation in Alzheimer's disease mutant mice
  Tchantchou, F., Xu Y., Wu Y., Christen Y., Luo Y. - 2007

  AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS   NEUROGENESIS AND PLASTICITY   PROTEINS AND GENES
Contained in: Neuropharmacology, 2007: 53, 699-723

Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system - too little activation is bad, too much is even worse

Authors: Parsons, C.G., Stoffler A., Danysz W.

  Memantine on NMDA/glutamate system and cognition - Review
  Parsons, C.G., Stoffler A., Danysz W. - 2007

  GLUTAMATE   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS   REVIEWS AND COMMENTARIES
Contained in: Psychopharmacology, 2007: 192, 275-282

The PDE4 inhibitor rolipram reverses object memory impairment induced by acute tryptophan depletion in the rat

Authors: Rutten, K., Liben C., Smits L., Blokland A.

  Rolipram on tryptophan depletion memory deficit in rats
  Rutten, K., Liben C., Smits L., Blokland A. - 2007

  NOOTROPICS   SEROTONIN

2006

Contained in: Pharmacol. Biochem. Behav., 2006: 83, 603-611

Effects of huperzine A on memory deficits and neurotrophic factors production after transient cerebral ischemia and reperfusion in mice

Authors: Wang, Z.F., Tang L.L., Yan H., Wang Y.J., Tang X.C.

  Oral huperzine A on hippocampal and cortical neurotrophins and mitogen-activated protein kinase/extracellular signal-regulated kinase and on spatial learning deficit by cerebral ischemia in mice
  Wang, Z.F., Tang L.L., Yan H., Wang Y.J., Tang X.C. - 2006

  ACETYLCHOLINE   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NOOTROPICS   PROTEIN KINASES
Contained in: Brain Res., 2006: 1097, 216-223

Cerebral ischemia combined with β-amyloid impairs spatial memory in the eight-arm radial maze task in rats

Authors: Iwasaki, K., Egashira N., Hatip-Al-Khatib I., Akiyoshi Y., Arai T., Takagaki Y., Watanabe T., Mishima K., Fujiwara M.

  Cerebral ischemia and beta-amyloid on hippocampal acetylcholine and spatial memory of rats
  Iwasaki, K., Egashira N., Hatip-Al-Khatib I., Akiyoshi Y., Arai T., Takagaki Y., Watanabe T., Mishima K., Fujiwara M. - 2006

  ACETYLCHOLINE   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2006: 85, 50-56

Evaluation of acute tacrine treatment on passive-avoidance response, open-field behaviour, and toxicity in 17- and 30-day-old mice

Authors: Pan, S.Y., Han Y.F., Yu Z.L., Yang R., Dong H., Ko K.M.

  Tacrine on passive avoidance, locomotion and exploration of 17- and 30-day-old mice
  Pan, S.Y., Han Y.F., Yu Z.L., Yang R., Dong H., Ko K.M. - 2006

  ACETYLCHOLINE   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   AVOIDANCE   AGE   NOOTROPICS
Contained in: Pharmacol. Biochem. Behav., 2006: 85, 253-260

Beneficial effects of galantamine on performance in the object recognition task in Swiss mice: deficits induced by scopolamine and by prolonging the retention interval

Authors: De Bruin, N., Pouzet B.

  Galantamine on object recognition memory deficit by scopolamine and by retention delay in mice
  De Bruin, N., Pouzet B. - 2006

  ACETYLCHOLINE   NOOTROPICS
Contained in: Brain Res., 2006: 1121, 207-215

Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia

Authors: Micale, V., Leggio G.M., Mazzola C., Drago F.

  5-HT4 receotr agonist effects on amnesia in mice
  Micale, V., Leggio G.M., Mazzola C., Drago F. - 2006

  AMNESIA   AVOIDANCE   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   NEUROPEPTIDES   NOOTROPICS   NUCLEUS BASALIS MAGNOCELLULARIS   SEROTONIN
Contained in: Neuropharmacology, 2006: 51, 1146-1155

The role of group I metabotropic glutamate receptors in acquisition and expression of contextual and auditory fear conditioning in rats - a comparison

Authors: Gravius, A., Barberi C., Schafer D., Schmidt W.J., Danysz W.

  Metabotropic glutamate receptors on acquisition and expression of fear conditioning in rats
  Gravius, A., Barberi C., Schafer D., Schmidt W.J., Danysz W. - 2006

  ANXIOLYTIC DRUGS   ACETYLCHOLINE   FEAR AND RELATED BEHAVIORS   GLUTAMATE   N-METHYL-D-ASPARTATE (NMDA)   NOOTROPICS   RECALL AND RECONSOLIDATION
Contained in: Behav. Brain Res., 2006: 170,<u> </u>233-240

Administration of raloxifene reduces sensorimotor and working memory deficits following traumatic brain injury

Authors: Kokiko, O.N., Murashov A.K., Hoane M.R.

  Estrogen agonist roloxifene on traumatic brain injury behavioral and cognitive deficits in rats
  Kokiko, O.N., Murashov A.K., Hoane M.R. - 2006

  LOCOMOTOR ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   SPATIAL ORIENTATION AND SPATIAL MEMORY   GONADAL HORMONES   NOOTROPICS
Contained in: NeuroReport, 2006: 17, 105-108

Linoleic acid derivative DCP-LA improves learning impairment in SAMP8

Authors: Yaguchi, T., Nagata T., Mukasa T., Fujikawa H., Yamamoto H., Yamamoto S., Iso H., Tanaka A., Nishizaki T.

  Systemic linoleic and derivate on learning in senescence-accelerated mice
  Yaguchi, T., Nagata T., Mukasa T., Fujikawa H., Yamamoto H., Yamamoto S., Iso H., Tanaka A., Nishizaki T. - 2006

  AVOIDANCE   SPATIAL ORIENTATION AND SPATIAL MEMORY   AGE   NOOTROPICS
Contained in: Psychopharmacology, 2006: 183, 439-445

Phosphodiesterase inhibition by sildenafil citrate attenuates a maze learning impairment in rats induced by nitric oxide synthase inhibition

Authors: Devan, B.D., Bowker J.L., Duffy K.B., Bharati I.S., Jimenez M., Sierra-Mercado D. Jr., Nelson C.M., Spangler E.L., Ingram D.K.

  Phosphodiesterase inhibition on T-maze avoidance impairment induced by nitric oxide inhibition in rats
  Devan, B.D., Bowker J.L., Duffy K.B., Bharati I.S., Jimenez M., Sierra-Mercado D. Jr., Nelson C.M., Spangler E.L., Ingram D.K. - 2006

  AVOIDANCE   SPATIAL ORIENTATION AND SPATIAL MEMORY   NITRIC AND NITROUS OXIDE   NOOTROPICS
Contained in: Behav. Brain Res., 2006: 169, 181-185

Zaprinast consolidates long-term memory when administered to neonate chicks trained using a weakly reinforced single trial passive avoidance task

Authors: Campbell, E., Edwards T.

  Endocerebral zaprinast on passive avoidance in day-old chicks
  Campbell, E., Edwards T. - 2006

  AVOIDANCE   NOOTROPICS
Contained in: Behav. Brain Res., 2006: 173, 112-115

Crocus sativus L. extracts antagonize memory impairments in different behavioural tasks in the rat

Authors: Pitsikas, N., Sakellaridis N.

  Crocus sativus extract on memory deficit of rats
  Pitsikas, N., Sakellaridis N. - 2006

  AVOIDANCE   ACETYLCHOLINE   NOOTROPICS
Contained in: Brain Res., 2006: 1109, 201-206

Protective effect of N-acetyl-L-cysteine on amyloid β-peptide-­induced learning and memory deficits in mice

Authors: Fu, A.-L., Dong Z.-H., Sun M.-J.

  N-acetyl-L-cysteine on intracerebroventricular amyloid &beta; peptide-induced memory impairment in mice
  Fu, A.-L., Dong Z.-H., Sun M.-J. - 2006

  AVOIDANCE   SPATIAL ORIENTATION AND SPATIAL MEMORY   NOOTROPICS