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2017
Behavioural pharamcology of the α5-GABAA receptor antagonist S44819: enhacement and remediation of cognitive performance in preclinical models
Authors: Gacsalyi, I., Moricz K., Gigler G., Wellmann J., Nagy K., Ling I., Barkoczy J., Haller J., Lambert J.J., Szenasi G., Spedding M., Antoni F.A. α5-GABA-A antagonist S44819 on social interaction, response to stress, object recognition, social avoidance, fear conditioning extinction, fear potentiated startle and spatial learning in mice: effects on ketamine and phencyclidine amnesic exposure
Gacsalyi, I., Moricz K., Gigler G., Wellmann J., Nagy K., Ling I., Barkoczy J., Haller J., Lambert J.J., Szenasi G., Spedding M., Antoni F.A. - 2017
LTP as hilar mossy cell-dentate granule cell synapses modulates dentate gyrus output by increasing excitation/inhibition balance
Authors: Hashimotodani, Y., Nasrallah K., Jensen K.R., Chavez A.E., Carrera D., Castillo P.E. Excitatory hylar mossy cells-dentate granule cells recurrent circuit excitation/inhibition balance in hippocampal long-term potentiation of rats
Hashimotodani, Y., Nasrallah K., Jensen K.R., Chavez A.E., Carrera D., Castillo P.E. - 2017
Aberrant connections between climbing fibers and Purkinje cells induce alterations in the timing of an instrumental response in the rat
Authors: Gaytan-Tocaven, L., Lopez-Vazquez M.A., Guevara M.A., Olvera-Cortes M.E. Early-life MK-801 exposure on cerebellar neuronal connections and related appetitive spatial learning impairment in adult rats
Gaytan-Tocaven, L., Lopez-Vazquez M.A., Guevara M.A., Olvera-Cortes M.E. - 2017
Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats
Authors: Sommer, J.B., Bach A., Malà H., Stromgaard K., Mogensen J., Pickering D.S. PSD-95 inhibitor UCCB01-144 on fimbria-fornix transection effects on spatial learning in rats
Sommer, J.B., Bach A., Malà H., Stromgaard K., Mogensen J., Pickering D.S. - 2017
Acute spinal cord injury diminishes silent synapses in the rat hippocampus
Authors: Jing, Y., Bai F., Chen H., Dong H. Spinal cord injury and ippocampal neuron excitability in rats: NR2B receptor role
Jing, Y., Bai F., Chen H., Dong H. - 2017
Long term impairment of cognitive functions ald alterations of NMDAR subunits after continuous microwave exposure
Authors: Wang, H., Tan S., Xu X., Zhao L., Zhang J., Yao B., Gao Y., Zhou H., Peng R. Microwave exposure on hippocampal structure, NMDA receptor expression, electroencephalographic activity, body temperature and Morris water maze performance in rats
Wang, H., Tan S., Xu X., Zhao L., Zhang J., Yao B., Gao Y., Zhou H., Peng R. - 2017
Prenatal high sucrose intake affected learning and memory of aged rat pffspring with abnormal oxidative stress and NMDARs/Wnt signaling in the hippocampus
Authors: He, A., Zhang Y., Yang Y., Li L., Feng X., Wei B., Zhu D., Liu Y., Wu L., Zhang L., Xu Z., Sun M. Prenatal high sucrose intake on hippocampal oxidative stress levels, NMDA receptor expression and spatial learning in aged rat offspring
He, A., Zhang Y., Yang Y., Li L., Feng X., Wei B., Zhu D., Liu Y., Wu L., Zhang L., Xu Z., Sun M. - 2017
α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B
Authors: Ferreira, D.G., Temido-Ferreira M., Miranda H.V., Batalha V.L., Coelho J.E., Szego E.M., Marques-Morgado I., Vaz S.H., Rhee J.S., Schmitz M., Zerr I., Lopes L.V., Outeiro T.F. α-Synuclein and prion protein on hippocampal neuron excitability, NMDA expression and spatial learning in mice
Ferreira, D.G., Temido-Ferreira M., Miranda H.V., Batalha V.L., Coelho J.E., Szego E.M., Marques-Morgado I., Vaz S.H., Rhee J.S., Schmitz M., Zerr I., Lopes L.V., Outeiro T.F. - 2017
Risperidone ameliorates cognitive deficits, promotes hippocampal proliferation, and enhances Notch signaling in a urine model schizophrenia
Authors: Xue, F., Chen Y.-C., Zhou C.-H., Wang Y., Cai M., Yan W.-J., Wu R., Wang H.-N., Peng Z.-W. Risperidone exposure on MK-801-induced effects on hippocampal adult neurogenesis/Notch signaling levels and spatial learning in mice
Xue, F., Chen Y.-C., Zhou C.-H., Wang Y., Cai M., Yan W.-J., Wu R., Wang H.-N., Peng Z.-W. - 2017
Integration of contextual cues into memory depends on "prefrontal" N-methyl-D-aspartate receptors
Authors: Starosta, S., Bartetzko I., Stuttgen M.C., Gunturkun O. Intra-like-prefrontal AP5 on contextual control during operant acquisition and extinction in pigeons
Starosta, S., Bartetzko I., Stuttgen M.C., Gunturkun O. - 2017
Regulation of sustained attention, false alarm responding and implementation of conditional rules by prefrontal GABAA transmission: comparison with NMDA transmission
Authors: Auger, M.L., Meccia J., Floresco S.B. Intra-prefrontal GABA-A or NMDA antagonist on operant discrimination attentional task in rats
Auger, M.L., Meccia J., Floresco S.B. - 2017
The beneficial effects of dietary restriction on learning are distinct from its effects on longevity and mediated by depletion of a neuroinhibitory metabolite
Authors: Vohra, M., Lemieux G.A., Lin L., Ashrafi K. Dietary restriction, kinurenic acid levels, NMDA signaling and associative learning in nematodes
Vohra, M., Lemieux G.A., Lin L., Ashrafi K. - 2017
The AMPA receptor positive allosteric modulator S 47445 rescues in vivo CA3-CA1 long-term potentiation and structural synaptic changes in old mice
Authors: Giralt, A., Gomez-Climent M.A., Alcalà R., Bretin S., Bertrand D., Delgado-Garcia J.M., Perez-Navarro E., Alberch J., Gruart A. AMPA receptor modulation on hippocampal neuron excitability/plasticity in young adult and old mice
Giralt, A., Gomez-Climent M.A., Alcalà R., Bretin S., Bertrand D., Delgado-Garcia J.M., Perez-Navarro E., Alberch J., Gruart A. - 2017
Sleep slow oscillation and plasticity
Authors: Timofeev, I., Chauvette S. "Synaptic homeostasis hypothesis", sleep and neuronal plasticity - Review
Timofeev, I., Chauvette S. - 2017
Involvement of extracellular signal-regulated kinase (ERK) in the short and long-lasting antidepressant-like activity of NMDA receptor antagonists (zinc and Ro 25-6981)in the forced swim test in rats
Authors: Pochwat, B., Rafalo-Ulinska A., Domin H., Misztak P., Nowak G., Szewczyk B. Extracellular signal-regulated kinase modulation on NMDA antagonist effects on response to stress and locomotor activity in rats: prefrontal extracellular signal-regulated kinase phosphorylation level study
Pochwat, B., Rafalo-Ulinska A., Domin H., Misztak P., Nowak G., Szewczyk B. - 2017
Cocaine promotes coincidence detection and lowers induction threshold during Hebbian associative synaptic potentiation in prefrontal cortex
Authors: Ruan, H., Yao W.-D. Cocaine and prefrontal neuron excitability in mice
Ruan, H., Yao W.-D. - 2017
Characteristics of ethanol-induced behavioral sensitization in rats: molecular mediators and cross-sensitization between ethanol and cocaine
Authors: Xu, S., Kang U.G. Ethanol consumption on cortical and striatal NMDA receptors and Egr-1 protein levels in rats: behavioral sensitization and ethanol and cocaine cross-sensitization study
Xu, S., Kang U.G. - 2017
The effect of hippocampal NMDA receptor blockade by MK-801 on cued fear extinction
Authors: Zhang, B., Li C.-Y., Wang X.-S. Intra-hippocampal MK-801 on fear conditioning extinction in rats
Zhang, B., Li C.-Y., Wang X.-S. - 2017
On the transition from reconsolidation to extinction of contextual fear memories
Authors: Cassini, L.F., Flavell C.R., Amaral O.B., Lee J.L.C. MK-801 on fear conditioning extinction and reconsolidation in rats
Cassini, L.F., Flavell C.R., Amaral O.B., Lee J.L.C. - 2017
Pharmacological evidence that a failure to recruit NMDA receptors contributes to impaired fear extinction retention in adolescent rats
Authors: Baker, K.D., Richardson R. NMDA modulation on fear conditioning extinction in adolescent rats
Baker, K.D., Richardson R. - 2017
Intrinsic cellular and molecular properties of in vivo hippocampal synaptic plasticity are altered in the absence of key synaptic matrix molecules
Authors: Jansen, S., Gottschling C., Faissner A., Manahan-Vaughan D. Hippocampal extracellular matrix protein on neuron excitability and receptor expression in mice
Jansen, S., Gottschling C., Faissner A., Manahan-Vaughan D. - 2017
Closing the gap: long-term presynaptic plasticity in brain function and disease
Authors: Monday, H.R., Castillo P.E. Long-term presynaptic plasticity - Review
Monday, H.R., Castillo P.E. - 2017
Involvement of NMDA receptors in the antidepressant-like effect of tramadol in the mouse forced swimming test
Authors: Ostadhadi, S., Norouzi-Javidan A., Chamanara M., Akbarian R., Imran-Khan M., Ghasemi M., Dehpour A.-R. NMDA modulation on antidepressant effects of tramadol in forced swimming test response of mice
Ostadhadi, S., Norouzi-Javidan A., Chamanara M., Akbarian R., Imran-Khan M., Ghasemi M., Dehpour A.-R. - 2017
Chronic impairment of ERK signaling in glutamatergic neurons of the forebrain does not affect spatial memory retention and LTP in the same manner as acute blockade of the ERK pathway
Authors: Vithayathil, J., Pucilowska J., Friel D., Landreth G.E. Extracellular-signal-regulated kinase signaling role in hippocampal neuron excitability, PSD95 protein level, GRIA1-GRIN2A-GRIN2B receptor expression, exploratory activity, object recognition and Morris water maze performance in mice
Vithayathil, J., Pucilowska J., Friel D., Landreth G.E. - 2017
Memory trace reactivation and behavioral response during retrieval are differentially modulated by amygdalar glutamate receptors activity: interaction between amygdala and insular cortex
Authors: Osorio-Gomez, D., Guzman-Ramos K., Bermudez-Rattoni F. Amygdalar NMDA or glutamate antagonist on insular cortex glutamate, norepinephrine and dopamine levels related to conditioned taste aversion retrieval in rats: pre-retrieval intra-insular NMDA, glutamate, dopamine or norepinephrine antagonists effects
Osorio-Gomez, D., Guzman-Ramos K., Bermudez-Rattoni F. - 2017
Role of the astroglial glutamate exchanger xCT in ventral hippocampus in resilience to stress
Authors: Nasca, C., Bigio B., Zelli D., de Angelis P., Lau T., Okamoto M., Soya H., Ni J., Brichta L., Greengard P., Neve R.L., Lee F.S., McEwen B.S. Fluoxetine, acetyl-L-carnitine or acetyl-N-cysteine on stress effects on hippocampal astroglial glutamate exchanger xCT, social interactions and response to stress in mice
Nasca, C., Bigio B., Zelli D., de Angelis P., Lau T., Okamoto M., Soya H., Ni J., Brichta L., Greengard P., Neve R.L., Lee F.S., McEwen B.S. - 2017
Increased prevalence of calcium transients across the dendritic arbor during place field formation
Authors: Sheffield, M.E.J., Adoff M.D., Dombeck D.A. Hippocampal place cell excitability and polasticity related to novel environment exposure in mice: NMDA receptor role
Sheffield, M.E.J., Adoff M.D., Dombeck D.A. - 2017
Methoxetamine produces rapid and sustained antidepressant effects probably via glutamatergic and serotonergic mechanisms
Authors: Botanas, C.J., de la Pena J.B., Custodio R.J., dela Pena I.J., Kim M., Woo T., Kim H.J., Kim H.I., Cho M.C., Lee Y.S., Cheong J.H. NMDA antagonist, AMPA antagonist or 5-HT2 antagonist on hippocampal brain-derived neurotrophic factor, GluA1/2 and 5-HT2 receptor expression, locomotion/exploration, response to stress, neophobia and sucrose preference in mice
Botanas, C.J., de la Pena J.B., Custodio R.J., dela Pena I.J., Kim M., Woo T., Kim H.J., Kim H.I., Cho M.C., Lee Y.S., Cheong J.H. - 2017
Dendritic GIRK channels gate the integration window, plateau potentials, and induction of synaptic plasticity on dorsal but not ventral CA1 neurons
Authors: Malik, R., Johnston D. GIRK potassium channel role in hippocampal neuron excitability in rats
Malik, R., Johnston D. - 2017
Memory consolidation within the central amygdala is not necessary for modulation of cerebellar learning
Authors: Steinmetz, A.B., Ng K.H., Freeman J.H. Central amygdala role in fear conditioning and eyeblink conditioning acquisition and consolidation in rats
Steinmetz, A.B., Ng K.H., Freeman J.H. - 2017