2015

Contained in: Neuropharmacology, 2015: 97, 122-132

Simvastatin prevents β-amyloid25-35-impaired neurogenesis in hippocampal dentate gyrus through α7nAChR-dependent cascading PI3K-Akt and increasing BDNF via reduction of farnesyl pyrophosphate

Authors: Wang, C., Chen T., Li G., Zhou L., Sha S., Chen L.

  Simvastin on intracerebroventricular amygdaloid-β25-35-induced spatial learning, hippocampal neurogenesis/plasticity and extracellular signal-regulated kinase/brain-derived neurotropic factor effects in mice: α7 nicotinic acetylcholine receptor modulation
  Wang, C., Chen T., Li G., Zhou L., Sha S., Chen L. - 2015

  ACETYLCHOLINE   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NEUROGENESIS AND PLASTICITY   PROTEIN KINASES
Contained in: Pharmacol. Biochem. Behav., 2015: 133, 146-154

Antidepressant-like effects of oleoylethanolamide in a mouse model of chronic unpredictable mild stress

Authors: Jin, P., Yu H.-L., Tian-Lan, Zhang F., Quan Z.-S.

  Oleoylethanolamide on stress-induced prefrontal/hippocampal vbrain-derived neurorophic factor, serum sdreno-cortico-tropic-hormone/corticosterone, exploratory activity, rearing and neophobia in mice
  Jin, P., Yu H.-L., Tian-Lan, Zhang F., Quan Z.-S. - 2015

  ADRENO-CORTICO-TROPIC-HORMONE (ACTH)   EXPLORATORY ACTIVITY   CANNABINOIDS   CEREBRAL CORTEX   GLUCOCORTICOIDS   STEROTYPED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEOPHOBIA   NEUROTROPHIC FACTORS   STRESS
Contained in: Neurosci. Biobehav. Rev., 2015: 53, 160-190

Brain sites involved in fear memory reconsolidation and extinction of rodents

Authors: Baldi, E., Bucherelli C.
Contained in: Brain Res., 2015: 1622, 279-291

Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system

Authors: Jabaris, S.S.L., Sumathy H., Girish R., Narayanan S., Sugumar M., Babu C.S., Thanikachalam S., Thanikachalam M.

  Phosphodiesterase inhibitor on hippocampal CREB/brain-derived neurotrophic factor expression and object recognition impairment by deoxycorticosterone hypertensive rats
  Jabaris, S.S.L., Sumathy H., Girish R., Narayanan S., Sugumar M., Babu C.S., Thanikachalam S., Thanikachalam M. - 2015

  EPINEPHRINE AND NOREPINEPHRINE   GLUCOCORTICOIDS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   PROTEINS AND GENES
Contained in: Neurosci. Lett., 2015: 606, 1-6

Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice

Authors: Zhu, L., Wei T., Gao J., Chang X., He H., Miao M., Yan T.

  Salidroside and fluoxetine on lipopolysaccharide exposition effects on response to stress, blood cytokine levels, prefrontal serotonin/norepinephrine level and hippocampal brain-derived neurotrophic factor/tyrosine receptor kinase B/nuclear factor κ-light-chain-enhancer of activate B cells expression in mice
  Zhu, L., Wei T., Gao J., Chang X., He H., Miao M., Yan T. - 2015

  EPINEPHRINE AND NOREPINEPHRINE   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROPEPTIDES   NEUROTROPHIC FACTORS   SEROTONIN   STRESS
Contained in: Psychopharmacology, 2015: 232, 1095-1105

Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters

Authors: Aboul-Fotouh, S.

  Nicotinic antagonist mecamylamine on response to stress, sucrose preference social interaction, exploratory activity and prefrontal BDNF/serotonin/norepinephrine levels in rats
  Aboul-Fotouh, S. - 2015

  EPINEPHRINE AND NOREPINEPHRINE   EXPLORATORY ACTIVITY   ACETYLCHOLINE   ENVIRONMENT AND SOCIAL BEHAVIOR   CEREBRAL CORTEX   GLUCOCORTICOIDS   NEUROTROPHIC FACTORS   SEROTONIN   STRESS
Contained in: Trends Neurosci., 2015: 38, 800-812

Neurocognitive aging and the hippocampus across species

Authors: Leal, S.L., Yassa M.A.
Contained in: J. Neurosci., 2015: 35, 8308-8321

Role of hippocampal β-adrenergic and glucocorticoid receptors in the novelty-induced enhancement of fear extinction

Authors: Liu, J.-F., Yang C., Deng J.-H., Yan W., Luo Y.-X., Shi H.-S., Meng S.-Q., Chai B.-S., Fang Q., Chai N., Xue Y.-X., Sun J., Chen C., Wang X.-Y., Wang J.-S., Lu L.

  Intra-hippocampal propranolol, glucocorticoid antagonist, protein kinase A and extracellular signal-regulated kinase 1/2 inhibitors pre novelty-induced open field exposition administration on consolidate fear conditioning extinction and subcessive reinstatement in rats
  Liu, J.-F., Yang C., Deng J.-H., Yan W., Luo Y.-X., Shi H.-S., Meng S.-Q., Chai B.-S., Fang Q., Chai N., Xue Y.-X., Sun J., Chen C., Wang X.-Y., Wang J.-S., Lu L. - 2015

  EPINEPHRINE AND NOREPINEPHRINE   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   EXTINCTION   FEAR AND RELATED BEHAVIORS   GLUCOCORTICOIDS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   PROTEIN KINASES   RECALL AND RECONSOLIDATION   PROTEINS AND GENES
Contained in: Neurobiol. Learn. Mem., 2015: 118, 189-197

Running exercise delays neurodegeneration in amygdala and hippocampus of Alzheimer's disease (APP/PS1) transgenic mice

Authors: Lin, T.-W., Shih Y.-H., Chen S.-J., Lien C.-H., Chang C.-Y., Huang T.-Y., Chen S.-H., Jen C.J., Kuo Y.-M.

  Running exercise on amygdalar and hippocampal brain derived neurotrophic factor/protein kinases expression, plasticity and fear conditioning performance in APP/PS1 and control mice
  Lin, T.-W., Shih Y.-H., Chen S.-J., Lien C.-H., Chang C.-Y., Huang T.-Y., Chen S.-H., Jen C.J., Kuo Y.-M. - 2015

  AMYGDALA   LOCOMOTOR ACTIVITY   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NEUROGENESIS AND PLASTICITY   PROTEIN KINASES
Contained in: Behav. Brain Res., 2015: 276, 59-66

Sign-tracking to an appetitive cue predicts incubation of conditioned fear in rats

Authors: Morrow, J.D., Saunders B.T., Maren S., Robinson T.E.

  Pavlovian, operant and fear conditioning in rats: prefrontal, striatal, amygdalar and hippocampal brain derived neurotrophic factor levels
  Morrow, J.D., Saunders B.T., Maren S., Robinson T.E. - 2015

  AMYGDALA   OPERANT CONDITIONING   CLASSICAL PAVLOVIAN CONDITIONING   CEREBRAL CORTEX   FEAR AND RELATED BEHAVIORS   CONDITIONED AND UNCONDITIONED INHIBITION   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   STRIATUM
Contained in: Nature, 2015: 519, 455-459

The paraventricular thalamus controls a central amygdala fear circuit

Authors: Penzo, M.A., Robert V., Tucciarone J., De Bundel D., Wang M., Van Aelst L., Darvas M., Parada L.F., Palmiter R.D., He M., Huang J., Li B.

  Paraventricular thalamus on central amygdala role in fear response of mice
  Penzo, M.A., Robert V., Tucciarone J., De Bundel D., Wang M., Van Aelst L., Darvas M., Parada L.F., Palmiter R.D., He M., Huang J., Li B. - 2015

  AMYGDALA   FEAR AND RELATED BEHAVIORS   NEUROTROPHIC FACTORS   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION
Contained in: Nat. Neurosci., 2015: 18, 1353-1363

Mechanisms of stress in the brain

Authors: McEwen, B.S., Bowles N.P., Gray J.D., Hill M.N., Hunter R.G., Karatsoreos I.N., Nasca C.

  Stress effects and brain functions - Review
  McEwen, B.S., Bowles N.P., Gray J.D., Hill M.N., Hunter R.G., Karatsoreos I.N., Nasca C. - 2015

  AMYGDALA   CANNABINOIDS   CEREBRAL CORTEX   CORTICO-RELEASING-FACTOR (CRF)   GLUCOCORTICOIDS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NEUROGENESIS AND PLASTICITY   REVIEWS AND COMMENTARIES   PROTEINS AND GENES   STRESS
Contained in: Nat. Neurosci., 2015: 18, 1364-1375

Neighborhood matters: divergent patterns of stress-induced plasticity across the brain

Authors: Chattarji, S., Tomar A., Suvrathan A., Ghosh S., Rahman M.M.
Contained in: Brain Res. Bull., 2015: 118, 65-77

Exposure to sub-chronic unpredictable stress accounts for antidepressant-like effects in hamsters treated with BDNF and CNQX

Authors: Alò, R., Mele M., Fazzari G., Avolio E., Canonaco M.

  Intra-hippocampal brain-derived neurotrophic factor or AMPA antagonist on stress-induced sucrose consumption, response to stress, exploratory activity and brain tropomyosin-related kinase B/HSP70 protein expression impairment in hamsters
  Alò, R., Mele M., Fazzari G., Avolio E., Canonaco M. - 2015

  AMYGDALA   EXPLORATORY ACTIVITY   GLUTAMATE   HYPOTHALAMUS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   STRESS
Contained in: Neurosci. Lett., 2015: 588, 125-130

The change of circulating insulin like growth factor binding protein 7 levels may correlate with postoperative cognitive dysfunction

Authors: Jiang, J., Chen Z., Liang B., Yan J., Zhang Y., Xu H., Huang Y., Jiang H.

  Anesthesia and post-operative cognitive dysfunction in humans: insulin-like growth factor role
  Jiang, J., Chen Z., Liang B., Yan J., Zhang Y., Xu H., Huang Y., Jiang H. - 2015

  ANESTHESIA   NEUROTROPHIC FACTORS
Contained in: Psychopharmacology, 2015: 232, 663-672

Anxiolytic effects of ketamine in animal models of posttraumatic stress disorder

Authors: Zhang, L.-M., Zhou W.-W., Ji Y.-J., Li Y., Zhao N., Chen H.-X., Xue R., Mei X.-G., Zhang Y.-Z., Wang H.-L., Li Y.-F.

  Ketamine on response to stress, locomotion/exploration, fear conditioning and hippocampal brain derived neurotrophic factor in mice
  Zhang, L.-M., Zhou W.-W., Ji Y.-J., Li Y., Zhao N., Chen H.-X., Xue R., Mei X.-G., Zhang Y.-Z., Wang H.-L., Li Y.-F. - 2015

  ANXIOLYTIC DRUGS   EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   N-METHYL-D-ASPARTATE (NMDA)   STRESS
Contained in: Neuroscience, 2015: 284, 297-310

Brain-derived neurotrophic factor heterozygous mutant rats show selective cognitive changes and vulnerability to chronic corticosterone treatment

Authors: Gururajan, A., Hill R.A., Van Den Buuse M.

  Brain-derived neurotrophic factor levels on corticosterone response in rats on fera conditioning, prepulse inhibition of startle reflex, object recognition and spatial learning
  Gururajan, A., Hill R.A., Van Den Buuse M. - 2015

  PITUITARY-ADRENAL AXIS   SPATIAL ORIENTATION AND SPATIAL MEMORY   EXTINCTION   FEAR AND RELATED BEHAVIORS   GLUCOCORTICOIDS   CONDITIONED AND UNCONDITIONED INHIBITION   NEUROTROPHIC FACTORS   N-METHYL-D-ASPARTATE (NMDA)   STARTLE REFLEX
Contained in: Pharmacol. Biochem. Behav., 2015:132, 20-32

Type 4 phopshodiesterase enzyme inhibitor, rolipram rescues behavioral deficits in olfactory bulbectomy models of depression: involvement of hypothalamic-pituitary-adrenal axis, cAMP signaling aspects and antioxidant defense system

Authors: Jindal, A., Mahesh R., Bhatt S.

  Rolipram on olfactory bulbectomy effects on exploratory activity, neophobia, response to stress and oxidative stress response in rats: antidepressant effects extimation
  Jindal, A., Mahesh R., Bhatt S. - 2015

  EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   GLUCOCORTICOIDS   NEOPHOBIA   NEUROTROPHIC FACTORS   NOOTROPICS   SEROTONIN   PROTEINS AND GENES
Contained in: Pharmacol. Biochem. Behav., 2015: 312, 79-87

Beneficial effect of honokiol on lipopolysaccharide induced anxiety-like behavior and liver damage in mice

Authors: Sulakhiya, K., Kumar4 P., Gurjar S.S., Barua C.C., Hazarika N.K.

  Honokiol on lipopolysaccharide induced feeding/drinking, exploratory activity reduction and oxidative stress in mice
  Sulakhiya, K., Kumar4 P., Gurjar S.S., Barua C.C., Hazarika N.K. - 2015

  EXPLORATORY ACTIVITY   FEEDING AND DRINKING   NEUROPEPTIDES   NEUROTROPHIC FACTORS
Contained in: Behav. Brain Res., 2015: 278, 451-461

The effects of Ginkgo biloba extract on cognitive functions in aged female rats: the role of oxidative stress and brain-derived neurotrophic factor

Authors: Belviranli, M., Okudan N.

  Ginkgo biloba extract on exploratory activity and Morris water maze perfomance in female rats of different age
  Belviranli, M., Okudan N. - 2015

  EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   AGE   NEUROTROPHIC FACTORS   NOOTROPICS
Contained in: Neurobiol. Learn. Mem., 2015: 121, 12-19

Cranial irradiation regulates CREB-BDNF signaling and variant BDNF transcript levels in the mouse hippocampus

Authors: Son, Y., Yang M., Kang S., Lee S., Kim J., Kim J., Park S., Kim J.-S., Jo S.-K., Jung U., Shin T., Kim S.-H., Wang H., Moon C.

  Cranial irradiation on locomotion/exploration, object recognition, fear conditioning and hippocampal CREB and brainj derived neurotrophic factor expression in mice
  Son, Y., Yang M., Kang S., Lee S., Kim J., Kim J., Park S., Kim J.-S., Jo S.-K., Jung U., Shin T., Kim S.-H., Wang H., Moon C. - 2015

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   PROTEINS AND GENES
Contained in: Pharmacol. Biochem. Behav., 2015: 134, 22-30

Flavonoid Chrysin prevents age-related cognitive decline via attenuation of oxidative stress and modulation of BDNF levels in aged mouse brain

Authors: Souza, L.C., Antunes M.S., Filho C.B., Del Fabbro L., de Gomes M.G., Rossito Goes A.T., Donato F., Prigol M., Boeira S.P., Jesse C.R.

  Flavonoid Chrysin on oxidative stress, brain derived neurotrophic factor levels, exploratory activity and Morris water maze performance in adult and aged mice
  Souza, L.C., Antunes M.S., Filho C.B., Del Fabbro L., de Gomes M.G., Rossito Goes A.T., Donato F., Prigol M., Boeira S.P., Jesse C.R. - 2015

  EXPLORATORY ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   AGE   NEUROTROPHIC FACTORS   NOOTROPICS
Contained in: Neurosci. Lett., 2015: 597, 121-126

Nrf2-signaling and BDNF: a new target for the antidepressant-like activity of chronic fluoxetine treatment in a mouse model of anxiety/depression

Authors: Mendez-david, I., Tritschler L., Ali Z.E., Damiens M.-H., Pallardy M., David D.J., Kerdine-Romer S., Gardier A.M.

  Corticosterone and fluoxetine on hippocampal and cortical brain derived neurotrophic factor and Nrf2-transcription factor levels, neophobia and exploratory activity in mice
  Mendez-David, I., Tritschler L., Ali Z.E., Damiens M.-H., Pallardy M., David D.J., Kerdine-Romer S., Gardier A.M. - 2015

  EXPLORATORY ACTIVITY   CEREBRAL CORTEX   GLUCOCORTICOIDS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEOPHOBIA   NEUROTROPHIC FACTORS   SEROTONIN   PROTEINS AND GENES
Contained in: Physiol. Behav., 2015: 147, 359-363

Measure of anxiety-related behaviors and hippocampal BDNF levels associated to the amnesic effect induced by MK-801 evaluated in the modified elevated plus-maze in rats

Authors: Hill, X.L., Richeri A., Scorza C.

  MK-801 on exploratory activity and hippocampal brain derived neurotrophic factor levels in rats
  Hill, X.L., Richeri A., Scorza C. - 2015

  EXPLORATORY ACTIVITY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   N-METHYL-D-ASPARTATE (NMDA)
Contained in: Cell. Mol. Neurobiol., 2015: 35, 807-817

Time course of behavioral alteration and mRNA levels of neurotrophic factor following stress exposure in mouse

Authors: Hashikawa, N., Ogawa T., Sakamoto Y., Ogawa M., Matsuo Y., Zamami Y., Hashikawa-Hobara N.

  Chronic stress on hippocampal neurogenesis and nerve growth factor expression, locomotion/exploration, sucrose preference and response to stress in mice
  Hashikawa, N., Ogawa T., Sakamoto Y., Ogawa M., Matsuo Y., Zamami Y., Hashikawa-Hobara N. - 2015

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   GLUCOCORTICOIDS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NEUROGENESIS AND PLASTICITY   STRESS
Contained in: Behav. Brain Res., 2015: 286, 104-111

Time-dependent effects of rapamycin on consolidation of predator stress-induced hyperarousal

Authors: Fifield, K., Hebert M., Williams K., Linehan V., Whiteman J.D., Mac Callum P., Blundell J.

  Rapamycin on predator stress hyperarousal, exploratory activity and startle reflex in rats
  Fifield, K., Hebert M., Williams K., Linehan V., Whiteman J.D., Mac Callum P., Blundell J. - 2015

  EXPLORATORY ACTIVITY   DARK/LIGHT CONTEXT   NEUROTROPHIC FACTORS   STARTLE REFLEX   STRESS   CONSOLIDATION
Contained in: Proc. Natl. Acad. Sci. USA, 2015: 112, 11953-11958

Fibroblast growth factor 9 is a novel modulator of negative affect

Authors: Aurbach, E.L., Inui E.G., Turner C.A., Hagenauer M.H., Prater K.E., Li J.Z., Absher D., Shah N., Blandino P. Jr., Bunney W.E., Myers R.M., Barchas J.D., Schatzberg A.F., Watson S.J. Jr., Akil H.

  Hippocampal fibroblast5 growth factor 9 expression on locomotion/exploration and response to stress in rats and depression in humans
  Aurbach, E.L., Inui E.G., Turner C.A., Hagenauer M.H., Prater K.E., Li J.Z., Absher D., Shah N., Blandino P. Jr., Bunney W.E., Myers R.M., Barchas J.D., Schatzberg A.F., Watson S.J. Jr., Akil H. - 2015

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   STRESS
Contained in: Psychopharmacology, 2015: 232, 623-637

Etazolate, a phosphodiesterase-4 enzyme inhibitor produces antidepressant-like effects by blocking the behavioral, biochemical, neurological deficits and histological abnormalities in hippocampus region caused by olfactory bulbectomy

Authors: Jindal, A., Mahesh R., Bhatt S.

  Phosphodiesterase-4 inhibitor etazolate, fluoxetine and olfactory bulbectomy on brain oxidative stress, brain derived neurotrophic factor and CREB levels, response to stress, exploratory activity, startle response and sucrose preference in rats
  Jindal, A., Mahesh R., Bhatt S. - 2015

  EXPLORATORY ACTIVITY   CENTRAL NERVOUS SYSTEM LESIONS   GLUCOCORTICOIDS   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROTROPHIC FACTORS   NITRIC AND NITROUS OXIDE   PROTEINS AND GENES   STARTLE REFLEX   STRESS
Contained in: Behav. Brain Res., 2015: 290, 51-60

Tumor necrosis factor alpha and its receptors in behaviour and neurobiology of adult mice, in the absence of an immune challenge

Authors: Camara, M.L., Corrigan F., Jaehne E.J., Jawahar M.C., Anscomb H., Baune B.T.

  Tumor necrosis factor α expression on hippocampal nerve growth factor and brain derived neurotrophic factor expression, locomotion/exploration, spatial learning, response to stress and social interaction in mice
  Camara, M.L., Corrigan F., Jaehne E.J., Jawahar M.C., Anscomb H., Baune B.T. - 2015

  EXPLORATORY ACTIVITY   LOCOMOTOR ACTIVITY   SPATIAL ORIENTATION AND SPATIAL MEMORY   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROPEPTIDES   NEUROTROPHIC FACTORS   STRESS
Contained in: Nat. Neurosci., 2015: 18, 1464-1473

BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice

Authors: Korb, E., Herre M., Zucker-Scharff I., Darnell R.B., Allis C.D.

  Bromodomain and extra-terminal domain protein Brd4 role in transcription, exploratory activity, fear conditioning and object recognition in mice
  Korb, E., Herre M., Zucker-Scharff I., Darnell R.B., Allis C.D. - 2015

  EXPLORATORY ACTIVITY   FEAR AND RELATED BEHAVIORS   GLUTAMATE   NEUROTROPHIC FACTORS   PROTEINS AND GENES