2018

Contained in: Behav. Brain Res., 2018: 351, 161-167

Neurocircuitry of fear extinction in adult and juvenile rats

Authors: Ganella, D.E., Nguyen L.D., Lee-Kardashyan L., Kim L.E., Paolini A.G., Kim J.H.

  Prefrontal- or hippocampal-projecting basolateral amygdala neuron activation related to fear conditioning retrieval and extinction in juvenile and adult rats
  Ganella, D.E., Nguyen L.D., Lee-Kardashyan L., Kim L.E., Paolini A.G., Kim J.H. - 2018

  AGE   FEAR AND RELATED BEHAVIORS   EXTINCTION   PROTEINS AND GENES   AMYGDALA   HIPPOCAMPUS, FORNIX AND SUBICULUM   RECALL AND RECONSOLIDATION   CEREBRAL CORTEX
Contained in: Behav. Brain Res., 2018: 351, 138-151

Rats with ventral hippocampal damage are impaired at various forms of learning including conditioned inhibition, spatial navigation, and iscriminative fear conditioning to similar contexts

Authors: McDonald, R.J., Balog R.J., Lee J.Q., Stuart E.E., Carrels B.B., Hong N.S.

  Ventral hippocampal lesions on conditioned inhibitory/reversal learning, contextual fear conditioning and spatial learning in rats
  McDonald, R.J., Balog R.J., Lee J.Q., Stuart E.E., Carrels B.B., Hong N.S. - 2018

  HIPPOCAMPUS, FORNIX AND SUBICULUM   CENTRAL NERVOUS SYSTEM LESIONS   CONDITIONED AND UNCONDITIONED INHIBITION   SPATIAL ORIENTATION AND SPATIAL MEMORY   FEAR AND RELATED BEHAVIORS   CLASSICAL PAVLOVIAN CONDITIONING
Contained in: Brain Res. Bull., 2018: 142, 297-303

Deltamethrin intranasal administration induces memory, emotional and tyrosine hydroxylase immunoreactivity alterations in rats

Authors: Souza, M.F., Freire M.A.M., Medeiros K.A.A.L., Lins L.C.R.F., Bispo J.M.M., Gois A.M., Leal P.C., Engelberth R.C.G.J., Ribeiro A.M., Silva R.H., Marchioro M., Santos J.R.

  Deltamethrin pesticide on substantia nigra/ventral tegmental area tyrosine hydroxylase immunoreactivity, locomotion/exploration/grooming, spatial learning, fear conditioning and object recognition in rats
  Souza, M.F., Freire M.A.M., Medeiros K.A.A.L., Lins L.C.R.F., Bispo J.M.M., Gois A.M., Leal P.C., Engelberth R.C.G.J., Ribeiro A.M., Silva R.H., Marchioro M., Santos J.R. - 2018

  DOPAMINE   LOCOMOTOR ACTIVITY   FEAR AND RELATED BEHAVIORS   SPATIAL ORIENTATION AND SPATIAL MEMORY   STEROTYPED BEHAVIORS   EXPLORATORY ACTIVITY   SUBSTANTIA NIGRA   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION
Contained in: Behav. Brain Res., 2018: 352, 81-93

Animals, anxiety, and anxiety disorders: how to measure anxiety in rodents and why

Authors: Harro, J.
Contained in: Curr. Op. Neurobiol., 2018: 52, 60-64

Neuronal coding mechanisms mediating fear behavior

Authors: Rozeske, R.R., Herry C.

  Amygdala, prefrontal cortex, peraqueductal gray matter and fear behavior - Review
  Rozeske, R.R., Herry C. - 2018

  FEAR AND RELATED BEHAVIORS   REVIEWS AND COMMENTARIES   AMYGDALA   CEREBRAL CORTEX
Contained in: Curr. Op. Neurobiol., 2018: 52, 149-155

Reciprocal amygdala-prefrontal interactions in learning

Authors: Yizhar, O., Klavir O.

  Amygdala, prefrontal cortex and aversive/appetitive conditioning - Review
  Yizhar, O., Klavir O. - 2018

  AMYGDALA   CEREBRAL CORTEX   REVIEWS AND COMMENTARIES   FEAR AND RELATED BEHAVIORS   AVOIDANCE   OPERANT CONDITIONING
Contained in: Behav. Brain Res., 2018: 352, 28-34

The different baseline characteristics of cognitive behavior test bwteen Mongolian gerbils and rats

Authors: Wang, S., Feng D., Li Y., Wang Y., Sun X., Li X., LI C., Chen Z., Du X.

  Locomotion/exploration, grip strength recation, social interaction, sucrose preference, fear conditioning and spatial learning in gerbils and rats
  Wang, S., Feng D., Li Y., Wang Y., Sun X., Li X., LI C., Chen Z., Du X. - 2018

  EXPLORATORY ACTIVITY   ENVIRONMENT AND SOCIAL BEHAVIOR   FEAR AND RELATED BEHAVIORS   SPATIAL ORIENTATION AND SPATIAL MEMORY   AGGRESSIVE AND DEFENSIVE BEHAVIOR   LOCOMOTOR ACTIVITY
Contained in: Cell, 2018: 174, 59-71

Astrocytic activation generates de novo neuronal potentiation and memory enhamcement

Authors: Adamsky, A., Kol A., Kreisel T., Doron A., Ozeri-Engelhard N., Melcer T., Refaeli R., Horn H., Regev L., Groysman M., London M., Goshen I.

  Hippocampal astrocytes chemogenetic activation on neuron excitability, exploratory activity, fear consiitoning, spatial learning and related hippocampal neuron c-fos expression in mice
  Adamsky, A., Kol A., Kreisel T., Doron A., Ozeri-Engelhard N., Melcer T., Refaeli R., Horn H., Regev L., Groysman M., London M., Goshen I. - 2018

  HIPPOCAMPUS, FORNIX AND SUBICULUM   N-METHYL-D-ASPARTATE (NMDA)   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   SPATIAL ORIENTATION AND SPATIAL MEMORY   FEAR AND RELATED BEHAVIORS   PROTEINS AND GENES   EXPLORATORY ACTIVITY
Contained in: Behav. Brain Res., 2018: 353, 32-39

Mechanism of nitric oxide and acid-sensing ion channel 1a modulation of panic-like behaviour in the dorsal periaqueductal grey of the mouse

Authors: Zhou, P., Xu H.-S., Li M.-M., Chen X.-D., Wang J., Zhou H.-B., Chen L., Zhang N., Liu N.

  Periaqueductal gray NO modulation on local CaMKII expression and fear/defensive reaction in mice
  Zhou, P., Xu H.-S., Li M.-M., Chen X.-D., Wang J., Zhou H.-B., Chen L., Zhang N., Liu N. - 2018

  NITRIC AND NITROUS OXIDE   PROTEIN KINASES   AGGRESSIVE AND DEFENSIVE BEHAVIOR   FEAR AND RELATED BEHAVIORS
Contained in: Behav. Brain Res., 2018: 353, 161-167

Observational threat conditioning is induced by circa-strike activity burst but not freezing and requires visual attention

Authors: Hong, E.-H., Choi J.-S.

  Fear observational social learning in mice
  Hong, E.-H., Choi J.-S. - 2018

  FEAR AND RELATED BEHAVIORS   ENVIRONMENT AND SOCIAL BEHAVIOR   AGGRESSIVE AND DEFENSIVE BEHAVIOR   LUMINANCE AND VISION
Contained in: Behav. Brain Res., 2018: 353, 242-249

Premature hippocampus-dependent memory decline in middle-aged females of a genetic rat model of depression

Authors: Lim, P.H., Wert S.L., Tunc-Ozcan E., Marr R., Ferreira A., Redei E.E.

  Hippocampal/prefrontal/amygdalar insulin-like growth factor 1/2 expression and fear conditioning performance in female rats of different age and strain
  Lim, P.H., Wert S.L., Tunc-Ozcan E., Marr R., Ferreira A., Redei E.E. - 2018

  FEAR AND RELATED BEHAVIORS   AGE   HIPPOCAMPUS, FORNIX AND SUBICULUM   CEREBRAL CORTEX   AMYGDALA   NEUROTROPHIC FACTORS   LOCOMOTOR ACTIVITY
Contained in: Behav. Brain Res., 2018: 353, 57-61

The contribution of contextual fear in the anxiolytic effect of chlordiazepoxide in the fear-potentiated startle test

Authors: Zhao, Y., Bijlsma E.Y., Verdouw P.M., Garssen J., Groenink L.

  Contextual fear and benzodiazepine exposure on fear potentiated startle in rats
  Zhao, Y., Bijlsma E.Y., Verdouw P.M., Garssen J., Groenink L. - 2018

  FEAR AND RELATED BEHAVIORS   ANXIOLYTIC DRUGS   STARTLE REFLEX
Contained in: Learn. Motiv., 2018: 63, 1-10

Effects of extended extinction and multiple extinction contexts on ABA renewal

Authors: Krisch, K.A., Bandarian-Balooch S., Neumann D.L.

  Contextual conditioned fear extinction/renewal in humans
  Krisch, K.A., Bandarian-Balooch S., Neumann D.L. - 2018

  RECALL AND RECONSOLIDATION   EXTINCTION   FEAR AND RELATED BEHAVIORS   SCHEDULE INDUCED CONDITIONING AND BEHAVIOR
Contained in: Learn. Motiv., 2018: 63, 20-26

Pre-exposure and retrieval effects on generalization of contextual fear

Authors: Sevenster, D., de Oliveira Alvares L., D'Hooge R.

  Pre- and re-exposure on contextual fear generalization in mice
  Sevenster, D., de Oliveira Alvares L., D'Hooge R. - 2018

  GENERALIZATION   RECALL AND RECONSOLIDATION   CONTEXTUAL PRE-EXPOSURE AND RETRAINING   FEAR AND RELATED BEHAVIORS   SCHEDULE INDUCED CONDITIONING AND BEHAVIOR   LATENT INHIBITION   CONDITIONED AND UNCONDITIONED INHIBITION
Contained in: Learn. Motiv., 2018: 63, 105-125

Transfer between anticipatory and consummatory tasks involving reward loss

Authors: Glueck, A.C., Torres C., Papini M.R.

  "Successive negative contrast" phenomenon in anticipatory instrumental amd consummatory responses in rats: diverse transfer schedule study
  Glueck, A.C., Torres C., Papini M.R. - 2018

  CLASSICAL PAVLOVIAN CONDITIONING   FEAR AND RELATED BEHAVIORS   OPERANT CONDITIONING   SCHEDULE INDUCED CONDITIONING AND BEHAVIOR   EXTINCTION   CONDITIONED AND UNCONDITIONED INHIBITION   AVOIDANCE
Contained in: Neurobiol. Learn. Mem., 2018: 154, 37-53

Hippocampal network oscillations as mediators of behavioural metaplasticity: insights from emotional learning

Authors: Caliskan, G., Stork O.

  Hippocampal activity oscillation, plasticity and fear memory processes - Review
  Caliskan, G., Stork O. - 2018

  REVIEWS AND COMMENTARIES   HIPPOCAMPUS, FORNIX AND SUBICULUM   NEUROGENESIS AND PLASTICITY   SLEEP   FEAR AND RELATED BEHAVIORS   CONSOLIDATION   RECALL AND RECONSOLIDATION   EXTINCTION
Contained in: Nature, 2018: 557, 183-189

A midline thalamic circuit determines reactions to visual threat

Authors: Salay, L.D., Ishiko N., Huberman A.D.

  Ventral midline thalamus to prefrontal cortex and amygdala role in related visual threat conditioned emotional response and behavioral recation in mice: optogenetic and c-fos expression study
  Salay, L.D., Ishiko N., Huberman A.D. - 2018

  UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   FEAR AND RELATED BEHAVIORS   AMYGDALA   CEREBRAL CORTEX   PROTEINS AND GENES   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   CONDITIONED EMOTIONAL RESPONSE   EXPLORATORY ACTIVITY   CLASSICAL PAVLOVIAN CONDITIONING
Contained in: Nature, 2018: 557, 172-174

Connections that control defence strategy

Authors: Lin, D.

  Ventral midline thalamus and reaction to threat/fear situation in mice - Commentary
  Lin, D. - 2018

  REVIEWS AND COMMENTARIES   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   FEAR AND RELATED BEHAVIORS   AGGRESSIVE AND DEFENSIVE BEHAVIOR
Contained in: Nat. Neurosci., 2018: 21, 1421-1430

Dopamine neurons projecting to the posterior striatum reinforce avoidance of threatening stimuli

Authors: Menegas, W., Akiti K., Amo R., Uchida N., Watabe-Uchida M.

  Postrior striatal dopaminergic terminals role in avoidance response of mice
  Menegas, W., Akiti K., Amo R., Uchida N., Watabe-Uchida M. - 2018

  DOPAMINE   STRIATUM   AVOIDANCE   FEAR AND RELATED BEHAVIORS   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   CENTRAL NERVOUS SYSTEM LESIONS   NEOPHOBIA   SUBSTANTIA NIGRA   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION
Contained in: Nat. Neurosci., 2018: 21, 1294-1299

Double threat in striatal dopamine signaling

Authors: Siciliano, C.A., Mills F., Tye K.M.

  Midbrain dopaminergic to posterior striatum neuron role in fearfull/threat novelty stimulus value and related avoidance recation in mice - Commentary
  Siciliano, C.A., Mills F., Tye K.M - 2018

  STRIATUM   DOPAMINE   REVIEWS AND COMMENTARIES   UNSPECIFIC ASCENDING ACTIVATING SYSTEM PROJECTION   SUBSTANTIA NIGRA   AVOIDANCE   FEAR AND RELATED BEHAVIORS
Contained in: Nat. Neurosci., 2018: 21, 1412-1420

Restoring wild-type-like CA1 network dynamics and behavior during adulthood in a mouse model of schizophrenia

Authors: Marissal, T., Salazar R.F., Bertollini C., Mitel S., DeRoo M., Rodriguez I., Muller D., Carleton A.

  22q11 gene role in hippocampal CA1 pyramidal cell and parvalbumin interneuron excitability, locomotor activity, prepulse inhibition of the startle reflex and contextual fear conditioning in mice
  Marissal, T., Salazar R.F., Bertollini C., Mitel S., DeRoo M., Rodriguez I., Muller D., Carleton A. - 2018

  HIPPOCAMPUS, FORNIX AND SUBICULUM   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   PROTEINS AND GENES   LOCOMOTOR ACTIVITY   FEAR AND RELATED BEHAVIORS   CONDITIONED AND UNCONDITIONED INHIBITION   STARTLE REFLEX
Contained in: Neuron, 2018: 99, 163-178

The BDNF Val66Met prodomain disassembles dendritic spines altering fear extinction circuitry and behavior

Authors: Giza, J.I., Kim J., Meyer H.C., Anastasia A., Dincheva I., Zheng C.I., Lopez K., Bains H., Yang J., Bracken C., Liston C., Jing D., Hempstead B.L:

  Brain-derived neurotrophic role in hippocampal.prelimbic projection neuron plasticity, fear conditioning acquisition and extinction in mice of different age
  Giza, J.I., Kim J., Meyer H.C., Anastasia A., Dincheva I., Zheng C.I., Lopez K., Bains H., Yang J., Bracken C., Liston C., Jing D., Hempstead B.L: - 2018

  NEUROTROPHIC FACTORS   NEUROGENESIS AND PLASTICITY   FEAR AND RELATED BEHAVIORS   EXTINCTION   CEREBRAL CORTEX   HIPPOCAMPUS, FORNIX AND SUBICULUM   AGE
Contained in: Neuropharmacology, 2018: 138, 151-159

Sub-efficacious doses of phosphodiesterase 4 and 5 inhibitors improve memory in a mouse model of Alzheimer's disease

Authors: Gulisano W., Tropea M.R., Arancio O., Palmeri A., Puzzo D.

  Phosphodiesterase 4/5 inhibitors on novel object recognition, fear conditioning and Morris water maze performance in APP mice
  Gulisano W., Tropea M.R., Arancio O., Palmeri A., Puzzo D. - 2018

  NOOTROPICS   SPATIAL ORIENTATION AND SPATIAL MEMORY   FEAR AND RELATED BEHAVIORS
Contained in: Neuropharmacology, 2018: 138, 331-340

Synaptic modification by L-theanine, a natural constituent in green tea, rescues the impairment of hippocampal long-term potentiation and memory in AD mice

Authors: Zhu, G., Yang S., Xie Z., Wan X.

  L-theamine on hippocampal neuron excitability, dopamine/norepinephrine/protein kinase A phosphorylation levels and fear conditioning performance in APP/PS1 and control mice
  Zhu, G., Yang S., Xie Z., Wan X. - 2018

  HIPPOCAMPUS, FORNIX AND SUBICULUM   N-METHYL-D-ASPARTATE (NMDA)   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   PROTEIN KINASES   DOPAMINE   EPINEPHRINE AND NOREPINEPHRINE   NOOTROPICS   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   FEAR AND RELATED BEHAVIORS
Contained in: NeuroReport, 2018: 29, 1418-1424

Fear conditioning downregukates miR-138 expression in the hippocampus to facilitate the formation of fear memory

Authors: Li, D., Liu J., Li S., Yang J., Sun H., Wang A.

  Hippocampal microTNA-138 role in locomotion/exploration and fear conditioning learning in mice
  Li, D., Liu J., Li S., Yang J., Sun H., Wang A. - 2018

  HIPPOCAMPUS, FORNIX AND SUBICULUM   FEAR AND RELATED BEHAVIORS   LOCOMOTOR ACTIVITY   EXPLORATORY ACTIVITY   PROTEINS AND GENES
Contained in: Neuroscience, 2018: 388, 45-56

Chemogenetic manipulation of dorsal hippocampal astrocytes protects against the development of stress-enhanced fear learning

Authors: Jones, M.E., Paniccia J.E., Lebonville C.L., Reissner K.J., Lysle D.T.

  Hippocampal astrocytes role in fear conditioning training-induced stress and related hippocampal synaptic PSD95 protein levels in rats
  Jones, M.E., Paniccia J.E., Lebonville C.L., Reissner K.J., Lysle D.T. - 2018

  STRESS   FEAR AND RELATED BEHAVIORS   HIPPOCAMPUS, FORNIX AND SUBICULUM   PROTEINS AND GENES   NEUROGENESIS AND PLASTICITY
Contained in: Neuroscience, 2018: 388, 448-459

Aberrant amygdala-dependent fear memory in corticosterone-treated mice

Authors: Inagaki, R., Moriguchi S., Fukunaga K.

  Corticosterone exposure on basolateral amygdala c-fos/BDNF/CREB/ERK expression, neuron excitability-plasticity, exploratory activity and fear conditioning in mice
  Inagaki, R., Moriguchi S., Fukunaga K. - 2018

  GLUCOCORTICOIDS   AMYGDALA   FEAR AND RELATED BEHAVIORS   PROTEINS AND GENES   PROTEIN KINASES   NEUROTROPHIC FACTORS   SHORT- AND LONG-TERM POTENTIATION AND DEPRESSION   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   DARK/LIGHT CONTEXT   EXPLORATORY ACTIVITY
Contained in: Neuropharmacology, 2018: 139, 1-12

(2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray

Authors: Chou, D., Peng H.-Y., Lin T.-B., Lai C.-Y., Hsieh M.-C., Wen Y.-C., Lee A.-S., Wang H.-H., Yang P.-S., Chen G.-D., Ho Y.-C.

  Systemic or intra-ventrolateral periaqueductal gray ketamine metabolite 2R,6R-HNK jnection on learned helplessness stress-induced effects on periaqueductal neuron exciatbility, locomotor activity, response to stress and sucrose preference in rats: AMPA receptor modulation study
  Chou, D., Peng H.-Y., Lin T.-B., Lai C.-Y., Hsieh M.-C., Wen Y.-C., Lee A.-S., Wang H.-H., Yang P.-S., Chen G.-D., Ho Y.-C. - 2018

  STRESS   GLUTAMATE   LOCOMOTOR ACTIVITY   FEAR AND RELATED BEHAVIORS   ELECTRIC/MAGNETIC CENTRAL NERVOUS SYSTEM STIMULATION   N-METHYL-D-ASPARTATE (NMDA)
Contained in: Neuropharmacology, 2018: 139, 205-216

Contributions of medial prefrontal cortex to decision making involving risk of punishment

Authors: Orsini, C.A., Heshmati S.C., Graman T.S., Wall S.C., Bizon J.L., Setlow B.

  Prefrontal cortex role in operant responding in a rewarded/punished operant paradigm of rats: intra-prefrontal and systemic amphetamine effects
  Orsini, C.A., Heshmati S.C., Graman T.S., Wall S.C., Bizon J.L., Setlow B. - 2018

  CEREBRAL CORTEX   FEAR AND RELATED BEHAVIORS   OPERANT CONDITIONING   SCHEDULE INDUCED CONDITIONING AND BEHAVIOR   NEURAL REVERSIBLE INACTIVATIONS   DOPAMINE
Contained in: Neuropharmacology, 2018: 140, 100-106

Interplay between 5-HT2C and 5-HT1A receptors in the dorsal periaqueductal gray in the modulation of fear-induced antinociception in mice

Authors: Baptista-de-Souza, D., Pelarin V., Canto-de-Souza L., Nunes-de-Souza R.L., Canto-de-Souza A.

  Periaqueductal gray 5-HT2C/1A receptor role on exploratory activity and fear-induced antinocicpetion in mice
  Baptista-de-Souza, D., Pelarin V., Canto-de-Souza L., Nunes-de-Souza R.L., Canto-de-Souza A. - 2018

  SEROTONIN   NOCICEPTION   FEAR AND RELATED BEHAVIORS   EXPLORATORY ACTIVITY