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2017
Antidepressant-like activity of venlafaxine and clonidine in mice exposed to single prolonged stress - A model of post-traumatic stress disorder. Pharmacodynamic and molecular docking studies
Authors: Malikowska, N., Fijalkowski L., Nowaczyk A., Popik P., Salat K. Venlafaxine and clonidine on stress effects on forced swim test performance in mice
Malikowska, N., Fijalkowski L., Nowaczyk A., Popik P., Salat K. - 2017
Reduced hippocampal IL-10 expression, altered monoaminergic activity and anxiety and depressive-like behavior in female mice subjected to chronic social instability stress
Authors: Labaka, A., Gomez-Lazaro E., Vegas O., Perez-tejada J., Arregi A., Garmendia L. Stress on hippocampal cytokine/estrogen receptor, dopamine, norepinephrine and serotonin levels, hypothalamic estrogen, glucocorticoid receptor expression, plasma estrdaiol and corticosterone levels, sucrose preference and response to stress in male mice
Labaka, A., Gomez-Lazaro E., Vegas O., Perez-tejada J., Arregi A., Garmendia L. - 2017
Prediction of human efficacious antidepressant doses using the mouse forced swim test
Authors: Yuen, E., Swanson S., Witkin J.M. Mouse forced swim test as antidepressant efficacious doses in humans - Methods
Yuen, E., Swanson S., Witkin J.M. - 2017
Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice
Authors: Hara, Y., Ago Y., Taruta A., Hasebe S., Kawase H., Tanabe W., Tsukada S., Nakazawa T., Hashimoto H., Matsuda T., Takuma K. Haloperidol, risperidone and aripiprazole on prenatal exposure to valproic acid effects on prefrontal dendritic spine density, c-fos expression, dopamine, norepinephrine and serotonin levels, social interaction and object recognition in mouse offspring
Hara, Y., Ago Y., Taruta A., Hasebe S., Kawase H., Tanabe W., Tsukada S., Nakazawa T., Hashimoto H., Matsuda T., Takuma K. - 2017
A high-resolution in vivo atlas of the human brain's serotonin system
Authors: Beliveau, V., Ganz M., Feng L., Ozenne B., Hojgaard L., Fisher P.M., Svarer C., Greve D.N., Knudsen G.M. Human brain serotonin system in vivo Atlas- Methods
Beliveau, V., Ganz M., Feng L., Ozenne B., Hojgaard L., Fisher P.M., Svarer C., Greve D.N., Knudsen G.M. - 2017
Interaction effect between 5-HTTLPR and HTR1A RS6295 polymorphisms on the frontoparietal network
Authors: Long, H., Liu B., Wang C., Zhang X., Li J., Yu C., Jiang T. Serotonin transporter-linked polymorphic region 5-HTTLPR and serotonin 1A receptor (rs6295) genes on working memory performance and related cortical activity in humans
Long, H., Liu B., Wang C., Zhang X., Li J., Yu C., Jiang T. - 2017
Environmental enrichment reduces innate anxiety with no effect on depression-like behaviour in mice lacking the serotonin transporter
Authors: Rogers, J., Li S., Lanfumey L., Hannan A.J., Renoir T. Environmental enrichment on response to stress, locomotion, exploration and prepulse inhibition of startle reflex in serotonin trasnsporter knockout mice
Rogers, J., Li S., Lanfumey L., Hannan A.J., Renoir T. - 2017
HBK-15 protects mice from stress-induced behavioral disturbances and changes in corticosterone, BDNF, and NGF levels
Authors: Pytka, K., Gluch-Lutwin M., Kotanska M., Zmudzka E., Jakubczyk M., Waszkielewicz A., Janiszewska P., Walczak M. 5-HT1A and D2 antagonist HBK-15 on stress effects on hippocampal and prefrontal brain-derived neurotrophic factor and nerve growth factor levels, plasma corticosterone levels, locomotion/exploration, sucrose preference and response to stress in mice: effects on amphetamine- and MK-801-induced hyperlocomotion
Pytka, K., Gluch-Lutwin M., Kotanska M., Zmudzka E., Jakubczyk M., Waszkielewicz A., Janiszewska P., Walczak M. - 2017
Differential effects of neonatal SSRI treatments on hypoxia-induced behavioral changes in male and female offspring
Authors: Nagano, R., Nagano M., Nakai A., Takeshita T., Suzuki H. Post-natal serotonin re-uptake inhibitors exposure on prenatal hypoxia effects on prefrontal and hippocampal serotonin and dopamine levels, locomotion, exploration, response to stress, fear conditioning and prepulse inhibition of startle reflex in male and female adult mouse offspring
Nagano, R., Nagano M., Nakai A., Takeshita T., Suzuki H. - 2017
Clozapine blockade of MK-801-induced learning/memory impairment in the mEPM: role of 5-HT1A receptors and hippocampal BDNF levels
Authors: Hill, X.L., Richeri A., Scorza M.C. Serotonergic modulation of clozapine effects on MK-801-induced hippocampal brain-derived neurotrophic factor levels and lcomotion/exploration changes in rats
Hill, X.L., Richeri A., Scorza M.C. - 2017
Silymarin ameliorates experimentally induced depressive like behavior in rats: involvement of hippocampal BDNF signaling, inflammatory cytokines and oxidative stress response
Authors: Thakare, V.N., Aswar M.K., Kulkarni Y.P., Patil R.R., Patel B.M. Silymarin and fluoxetine on olfactory bulbectomy effects on hippocampal and cortical cytokines, dopamine noepinephrine, serotonin and brain-derived neurotrophic factor and serum corticosterone levels, exploration/rearing and response to stress in rats
Thakare, V.N., Aswar M.K., Kulkarni Y.P., Patil R.R., Patel B.M. - 2017
Cognitive impairment and gene expression alterations in a rodent model of binge eating disorder
Authors: Chawla, A., Cordner Z.A., Boersma G., Moran T.H. "Binge eating disorder" on cortical, ventral tegmental area, hippocampal and accumbal dopamine, brain-derived neurotrophic factor, serotonin and glutamate expression, exploratory activity, object recognition and spatial learning in rats
Chawla, A., Cordner Z.A., Boersma G., Moran T.H. - 2017
The antidepressant effect of melatonin and fluoxetine in diabetic rats is associated with a reduction of the oxidative stress in the prefrontal and hippocampal cortices
Authors: Rebai, R., Jasmin L., Boudah A. Melatonin and fluoxetine on prefrontal oxidative stress levels, locomotion/exploration and response to stress in diabetic and control rats
Rebai, R., Jasmin L., Boudah A. - 2017
Enriched environment combined with fluoxetine ameliorates depression-like behaviors and hippocampal SYP expression in a rat CUS model
Authors: Liu, C., Gu J.-Y., Han J.-H., Yan F.-L., Li Y., Lv T.-T., Zhao L.-Q., Shao Q.-J., Feng Y.-Y., Zhang X.-Y., Wang C.-H. Enviornmental enrichment and fluoxetine exposure on chronic stress effects on hippocampal synaptophysin expression, sucrose consumption and exploratory activity in rats
Liu, C., Gu J.-Y., Han J.-H., Yan F.-L., Li Y., Lv T.-T., Zhao L.-Q., Shao Q.-J., Feng Y.-Y., Zhang X.-Y., Wang C.-H. - 2017
Crassifoside H improve the depressive-like behavior of rats under chronic unpredictable mild stress: possible involved mechanisms
Authors: Zhang, Y., Ge J.-F., Wang F.-F., Liu F., Shi C., Li N. Crassifoside H and fluoxetine exposure on stress effects on hippocampal 5-HT1A receptor, extracellular signal-regulated kinase and brain-derived neurotrophic factor expression, hypothalamic corticotropin releasing factor and plasma corticosterone levels, sucrose preference, response to stress and locomotion/exploration/grooming in rats
Zhang, Y., Ge J.-F., Wang F.-F., Liu F., Shi C., Li N. - 2017
The antidepressant- and anxiolytic-like effects of fluoxetine and clozapine in chronically isolated rats involve inhibition of hippocampal TNF-α
Authors: Todorovic, N., Filipovic D. Fluoxetine and clozapine exposure on chronical isolaion effects on hippocampal oxidative stress, sucrose preference and exploratory activity in rats
Todorovic, N., Filipovic D. - 2017
Interaction between harmane, a class of β-carboline alkaloids, and the CA1 serotonergic system in modulation of memory acquisition
Authors: Nasehi, M., Ghadimi F., Khakpai F., Zarrindast M.-R. Hippocampal serotonergic modulation on hormone effects on locomotor activity and passive avoidance in mice
Nasehi, M., Ghadimi F., Khakpai F., Zarrindast M.-R. - 2017
Potentiation of morphine-induced antinociception and locomotion by citalopram is accompanied by anxiolytic-like effects
Authors: Varela, M.J., de la Rocha A.M.A., Diaz A., Lopez-Gimenez J.F. Citalopram modulation on morphine-induced nociception and locomotion in mice
Varela, M.J., de la Rocha A.M.A., Diaz A., Lopez-Gimenez J.F. - 2017
Amphetamine-related drugs neurotoxicity in humans and in experimental animals: main mechanisms
Authors: Moratalla, R., Khairnar A., Simola N., Granado N., Garcia-Montes J.R., Porceddu P.F., Tizabi Y., Costa G., Morelli M. Amphetamine-related drug abuse and neurotoxicity - Review
Moratalla, R., Khairnar A., Simola N., Granado N., Garcia-Montes J.R., Porceddu P.F., Tizabi Y., Costa G., Morelli M. - 2017
The effects of the 5-HT7 receptor on hippocampal long-term potentiation and apoptosis in a rat model of Alzheimer's disease
Authors: Hashemi-Firouzi, N., Komaki A., Asl S.S., Shahidi S. 5-HT7 agonist on hippocampal neuron apoptosis/excitability in streptozotocin-induced Alzheimer's disease rats
Hashemi-Firouzi, N., Komaki A., Asl S.S., Shahidi S. - 2017
Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects
Authors: Ibi, D., de la Fuente Revenga M., Kezunovic N., Muguruza C., Saunders J.M., Gaitonde S.A., Moreno J.L., Ijaz M.K., Santosh V., Kozlenkov A., Holloway T., Seto J., Garcia-Bea A., Kurita M., Mosley G.E., Jiang Y., Christoffel D.J., Callado L.F., Russo S.J., Dracheva S., Lopez-Gimenez J.F., Ge Y., Escalante C.R., Meana J.J., Akbarian S., Huntley G.W., Gonzalez-Maeso J. Antipsychotic-induced cortical 5-HT2A, nuclear factor kappa-light-chain-enhancer of activated B cells and histone deacetylase 2 cascade and synaptic plasticity in mice
Ibi, D., de la Fuente Revenga M., Kezunovic N., Muguruza C., Saunders J.M., Gaitonde S.A., Moreno J.L., Ijaz M.K., Santosh V., Kozlenkov A., Holloway T., Seto J., Garcia-Bea A., Kurita M., Mosley G.E., Jiang Y., Christoffel D.J., Callado L.F., Russo S.J., Dracheva S., Lopez-Gimenez J.F., Ge Y., Escalante C.R., Meana J.J., Akbarian S., Huntley G.W., Gonzalez-Maeso J. - 2017
Initiation of behavioral response to antidepressants by cholecystokinin neurons of the dentate gyrus
Authors: Medrihan, L., Sagi Y., Inde Z., Krupa O., Daniels C., Peyrache A., Greengard P. 5-HT1B receptors in hippocampal cholecystokinin inhibitory interneurons and response to antidepressants in mice
Medrihan, L., Sagi Y., Inde Z., Krupa O., Daniels C., Peyrache A., Greengard P. - 2017
Pharmacological evidence that 5-HT2C receptor blockade selectively improves decision making when rewards are paired with audiovisual cues in a rat gambling task
Authors: Adams, W.K., Barkus C., Ferland J.-M.N., Sharp T., Winstanley C.A. Serotonergic modulation on operant rat gambling task performance
Adams, W.K., Barkus C., Ferland J.-M.N., Sharp T., Winstanley C.A. - 2017
Increased temporal discounting after chronic stress in CHL1-deficient mice is reversed by 5-HT2C agonist RO 60-0175
Authors: Buhusi, M., Olsen K., Buhusi C.V. Cell adhesion molecule CHL1 role in operant responding and related accumbal, striatal and prefrontal c-fos expression in mice: 5-HT2C receptor modulation
Buhusi, M., Olsen K., Buhusi C.V. - 2017
Convergence of glycogen synthase kinase 3β and GR signaling in response to fluoxetine treatment in chronically stressed female and male rats
Authors: Mitic, M., Brkic Z., Lukic I., Adzic M. Chronic stress and fluoxetine on hippocampal glucocorticoid reecptor expression in male and female rats
Mitic, M., Brkic Z., Lukic I., Adzic M. - 2017
Mitochrondial estrogen receptors as a vulnerability factor of chronic stress and mediator of fluoxetine treatment in female and male rat hippocampus
Authors: Adzic, M., Mitic M., Radojcic M. Hippocampal neuron mitochondrial estrogen receptor role in response to stress and fluoxetine in male and female rats
Adzic, M., Mitic M., Radojcic M. - 2017
Sleep deprivation induces changes in 5-HT actions and 5-HT1A receptor expression in the rat hippocampus
Authors: Azizi, H., Hwang J., Suen V., Kang N.Z., Somvanshi R., Tadavarty R., Kumar U., Sastry B.R. Sleep deprivation on hippocampal neuron excitability/plasticity and 5-HT1A receptor expression in young rats
Azizi, H., Hwang J., Suen V., Kang N.Z., Somvanshi R., Tadavarty R., Kumar U., Sastry B.R. - 2017
Genome-wide transcriptome analysis of hippocampus in rats indicated that TLR/NLR signaling pathway was involved in the pathogenesis of depressive disorder induced by chronic restraint stress
Authors: Wang, Y., Jiang H., Meng H., Lu J., Li J., Zhang X., Yang X., Zhao B., Sun Y., Bao T. Acupuncture and fluoxetine on stress effects on hippocampal genome-wide transcriptome and sucrose preference in rats
Wang, Y., Jiang H., Meng H., Lu J., Li J., Zhang X., Yang X., Zhao B., Sun Y., Bao T. - 2017
The lateral habenula and the serotonergic system
Authors: Metzger, M., Bueno D., Lima L.B. Lateral habenula and serotonergic system - Review
Metzger, M., Bueno D., Lima L.B. - 2017
Chronic BMY7378 treatment alters behavioral circadian rhythms
Authors: Shankara, J.V., Orr A., Mychasiuk R., Antle M.C. BMY7378 5-HT1A modulation chronic exposure on hypothalamic and prefrontal 5-HT1A/B receptor expression and circadian locomotor activity in hamsters
Shankara, J.V., Orr A., Mychasiuk R., Antle M.C. - 2017